10 research outputs found
Nicotinic Acetylcholine Receptor Variants Are Related to Smoking Habits, but Not Directly to COPD
- Author
- AC Heath
- B Le Foll
- BR Celli
- BW Willemse
- CC van Diemen
- CC van Diemen
- Chunyu Liu
- CS Pomerleau
- D Lambrechts
- DF Heitjan
- Dirkje S. Postma
- HM Boezen
- I Cerveri
- JA Cunningham
- JC Barrett
- JD Fryer
- Judith M. Vonk
- K Keskitalo
- M Falcone
- M Mroziewicz
- M Nakajima
- M Quaak
- Marike H. Boezen
- Mateusz Siedlinski
- ME Piper
- ML Bondarev
- ML Pianezza
- N Caporaso
- PD Scanlon
- RB Weiss
- RJ Hung
- RP Young
- SD Grabus
- SF Saccone
- SG Pillai
- Simona E. Budulac
- T Ingebrigtsen
- TE Thorgeirsson
- TF Heatherton
- V Batra
- Wim Timens
- X Chen
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2011
- Field of study
Genome-wide association studies identified single nucleotide polymorphisms (SNPs) in the nicotinic acetylcholine receptors (nAChRs) cluster as a risk factor for nicotine dependency and COPD. We investigated whether SNPs in the nAChR cluster are associated with smoking habits and lung function decline, and if these potential associations are independent of each other. The SNPs rs569207, rs1051730 and rs8034191 in the nAChR cluster were analyzed in the Vlagtwedde-Vlaardingen cohort (n = 1,390) that was followed for 25 years. We used GEE and LME models to analyze the associations of the SNPs with quitting or restarting smoking and with the annual FEV1 decline respectively. Individuals homozygote (CC) for rs569207 were more likely to quit smoking (OR (95%CI) = 1.58 (1.05–2.38)) compared to wild-type (TT) individuals. Individuals homozygote (TT) for rs1051730 were less likely to quit smoking (0.64 (0.42; 0.97)) compared to wild-type (CC) individuals. None of the SNPs was significantly associated with the annual FEV1 decline in smokers and ex-smokers. We show that SNPs in the nAChR region are associated with smoking habits such as quitting smoking, but have no significant effect on the annual FEV1 decline in smokers and ex-smokers, suggesting a potential role of these SNPs in COPD development via smoking habits rather than via direct effects on lung function
Polarization Effects in Organic Dipole Photomotors
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Temperature Investigations in the Petroleum Industry
- Author
- A Bejan
- AF Everdingen Van
- AS Djamalova
- C Billy
- DI Dyakonov
- DJ Timko
- DL Katz
- EA Bondarev
- EC Bullard
- ED Sloan
- FR French
- G Espinosa-Paredes
- GV Bogomolov
- H Wilhelm
- HJ Ramey Jr
- HS Carslow
- IM Kutasov
- IM Kutasov
- IM Kutasov
- IM Kutasov
- IM Kutasov
- IM Kutasov
- IM Kutasov
- IM Kutasov
- IM Kutasov
- IM Kutasov
- IM Kutasov
- IM Kutasov
- IM Kutasov
- J Andaverde
- JC Jaeger
- JC Jaeger
- JT Hubbard
- JW Barker
- LC Tien
- LV Eppelbaum
- LV Eppelbaum
- LV Eppelbaum
- LV Eppelbaum
- M Pooladi-Darvish
- MA Goodman
- MF Hawkins Jr
- MF Middleton
- ML Drury
- ML Edwardson
- NA Tsytovich
- PE Gretener
- PY Shen
- R MacAndrew
- S Cao
- S Fomin
- S Lin
- SHF Mekhtiev
- SM Kuliev
- SW Churchill
- SW Sparrow
- TK Perkins
- WL Dowdle
- WP Kritikos
- Y Leblanc
- YM Proselkov
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Comparison of In Vitro Stereoselective Metabolism of Bupropion in Human, Monkey, Rat, and Mouse Liver Microsomes
- Author
- A Avdeef
- A Meyer
- AR Masters
- AW Bruijnzeel
- AZX Zhu
- BT Gufford
- CS Ferguson
- CW Schindler
- DL Dunner
- ED Kharasch
- F Grandas
- F Toselli
- FW Reimherr
- GE Swan
- J Davidson
- J Deveaugh-Geiss
- J Woodcock
- JA Ascher
- JALC Johnston
- JE Sager
- JN Connarn
- JN Connarn
- JN Connarn
- JY Khokhar
- JY Khokhar
- L Dalgaard
- L Skarydova
- LM Hesse
- M Fava
- M Sharon
- M-N Beyens
- MI Damaj
- MI Damaj
- MJ Hansard
- ML Bondarev
- ND Volkow
- NL Benowitz
- P Martin
- PH Silverstone
- R Coles
- RF Suckow
- RM Welch
- RN Golden
- S Miksys
- S Miksys
- SC Laizure
- SD Grabus
- SM Stahl
- TIFH Cremers
- TR Berigan
- V Agarwal
- W Kielbasa
- W Kielbasa
- X Wang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Vibrio tetraodonis sp. nov.: genomic insights on the secondary metabolites repertoire
- Author
- AS Zai
- BL Bassler
- Bruno Gomez-Gil
- Bruno S. Silva
- CC Thompson
- Cristiane C. Thompson
- D Coil
- Diogo A. Tschoeke
- DL McRose
- F Thompson
- Fabiano L. Thompson
- FL Thompson
- Gizele D. Garcia
- Grasiele R. Lopes
- GRS Amaral
- Gustavo P. R. Azevedo
- H Machado
- Hannah K. Mattsson
- I Grissa
- Jean Swings
- JM Walter
- JP Meier-Kolthoff
- Koko Otsuki
- L Du
- Livia Vidal
- LM RodrÃguez-R
- Luciane A. Chimetto Tonon
- M Nei
- MA Skinnider
- Mariana Campeão
- MJ Lee
- ML Guerinot
- MS Llewellyn
- PD Cotter
- PG Arnison
- R Chau
- R Overbeek
- R Schmieder
- RJ Case
- S Agarwal
- S Naik
- T Böttcher
- TP Legrand
- TP Legrand
- TW Giessen
- V Bondarev
- WB Whitman
- Y Liu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
An Analysis of Biosynthesis Gene Clusters and Bioactivity of Marine Bacterial Symbionts
- Author
- A Debbab
- A Gavriilidou
- A Hagstrom
- A Isnansetyo
- A Nakabachi
- A Penesyan
- A Uria
- AJ Moghaddam
- AJ Van Heel
- AL Waters
- AS Zai
- AV Manwar
- B Baral
- BO Bachmann
- C Harrington
- C Huang
- C Xue
- CA Bewley
- CM Brinkmann
- CM Rath
- D Prihoda
- D Versluis
- DJ Waters
- DS Dalisay
- E Hirose
- EW Schmidt
- F Feliatra
- F Tambadou
- FJ Reen
- FN Egerton
- G Olguin-Uribe
- H Sugita
- HB Bode
- HW Nutzmann
- I Miller
- I Raimundo
- IA Beleneva
- IZ Rosenberg
- J Chaston
- J Harjes
- J Kubanek
- J Linneman
- J Martin
- J Piel
- JC Kwan
- JJ Enticknap
- JM Winter
- JP McCutcheon
- JT Wibowo
- JW Blunt
- K Blin
- KC Belknap
- L Katz
- LM Naughton
- M Girao
- M Mansson
- M Metsa-Ketela
- M Oliynyk
- M Slattery
- MA Fischbach
- ME Rateb
- MH Medema
- ML Lemos
- N Adnani
- N Asano
- N Imamura
- N Viju
- N Viju
- N Viju
- N Viju
- N Webster
- O Gillor
- PJ Rutledge
- PN Tran
- R Alvarez-Alvarez
- R Bernasconi
- R Dahiya
- RA Long
- RG Soengas
- RP Singh
- S Agrawal
- S Bergmann
- S Crowley
- S Palomo
- S Romano
- S Satheesh
- SA Amin
- SD Bentley
- T Barsby
- T Egli
- T Netzker
- T Stein
- T Weber
- T Weber
- V Bondarev
- Y Mast
- Y Nakashima
- Y Song
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
References
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- MI Afanasiev
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- MJ Molina
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- MN Artemjeva
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- MO Andreae
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- MW Gery
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- R Atkinson
- R Eichman
- R Guicherit
- R Hagemann
- R Jeltes
- R Leifer
- R Persson
- R Sartorius
- R Zander
- RA Duce
- RA Hawley-Fedder
- RA Rasmussen
- RA Rasmussen
- RA Rasmussen
- RA Rasmussen
- RA Rasmussen
- RA Rasmussen
- RA Rasmussen
- RA Rasmussen
- RA Rasmussen
- RA Rasmussen
- RA Rasmussen
- RA Saunders
- RA Stepen
- RA Whitby
- RB Norton
- RC Harriss
- RD Cadle
- RD Matthews
- RE Dickinson
- RE Larson
- RE Lee Jr
- RE Newell
- RG Prinn
- RH Kagann
- RH Whittaker
- RJ Cicerone
- RJ Ferek
- RK Stevens
- RL Chuan
- RL Crouch
- RL Tanner
- RM Garreis
- RM Harrison
- RM Harrison
- RS Hutte
- RW Show
- S Gäb
- S Jiang
- S Koda
- S Marklund
- S Tanabe
- S Thorburn
- SA Penkett
- SA Penkett
- SC Wofsy
- SM Awramik
- SP Churkin
- T Class
- T Class
- T Tanaka
- TA Teplizkaja
- TC Sauer Jr
- TD Cooke
- TE Bidleman
- TG Mirchink
- U Platt
- U Schmidt
- U Schmidt
- V Vaeck
- VA Isidorov
- VA Isidorov
- VA Isidorov
- VA Isidorov
- VA Isidorov
- VA Isidorov
- VA Isidorov
- VA Isidorov
- VA Isidorov
- VA Isidorov
- VA Isidorov
- VB Bondarev
- VI Dianov-Klockov
- VI Nilov
- VP Aneja
- VV Anikiev
- VV Protopopov
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- WW Berg
- WW Bunn
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- Y Murakami
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- YL Yung
- YV Shulanov
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- Ø Hov
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1990
- Field of study
Drugs, their targets and the nature and number of drug targets
- Author
- A Achari
- A Dahchour
- A Duflos
- A El Zoeiby
- A Hopkins
- A Matagne
- A Polak-Wyss
- A Sonneville
- AC Allison
- AC Anderson
- Achim Meyer
- AE Maccubbin
- AF Ambrosio
- AH Ahn
- AH Krauss
- AK Roy
- AP Bajaj
- AP Carter
- AS Beutler
- AS Levenson
- B Bain
- B Chini
- B Schumacher
- B Spiegelberg
- B Staels
- BB Fredholm
- BL Roth
- BM Necela
- BP Zambrowicz
- BS Katzenellenbogen
- BS Lou
- C Bell
- C Carlberg
- C Plata
- C Stancu
- C Temperini
- CG Unson
- Christian Sinning
- CI Carswell
- CK Surratt
- CL Cheeseman
- CM Revankar
- CT Keith
- CT Supuran
- D Accili
- D Dressler
- D Faulds
- D Gautam
- D Schmidt
- D Vallone
- DA Coulter
- DA Matthews
- DA Pastel
- DB Longley
- DC Swinney
- DH Ellison
- DJ Triggle
- DL Earnshaw
- DM Jonker
- DM Roden
- DM Roden
- DP Calfee
- DR Hill
- DS Cooper
- DW Denning
- E Buchdunger
- E Kapic
- E Mutschler
- E Southam
- ED Hogestatt
- EF Nemeth
- EJ Hoffman
- EJ Topol
- EM Brown
- EN Petersen
- F Borges
- F Grotenhermen
- F Neumann
- F Pea
- F Rogerson
- F Schlunzen
- F Schlünzen
- FE Simons
- FM Ashcroft
- G Apic
- G Bartholini
- G Fisone
- G Fisone
- G Gamba
- G Jiang
- G Schneider
- G Tunnicliff
- GA Brent
- GB Baker
- GH Wynn
- GM Keating
- GR Painter
- GR Thatcher
- GW Pasternak
- H Gohlke
- H Priewer
- H Sugimoto
- HB Nader
- HG Bull
- HG Kress
- HJ Yoon
- HM Spronk
- HP Lipp
- HS White
- HY Meltzer
- I Kodama
- I Tiede
- ID Goldman
- II Ismailov
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- J Albanell
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- J Burgess
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- J Spizek
- J Striessnig
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- J Wegner
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- JC Beique
- JC Gomora
- JD Corbin
- JD Deupree
- JD Minna
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- JF Pizzolato
- JG Mills
- JG Robertson
- JG Su
- JH Noseworthy
- JI Weitz
- JJ Galligan
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- JM Harms
- JM Herbert
- JP Henry
- JP Hieble
- JR Colca
- JS Mitcheson
- JW Yarbro
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- K Drlica
- K Komo
- K Krishnan
- K Nemec
- KA Bauer
- KA Wafford
- KC Lamp
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- KG Mann
- KV Pinette
- L Adnane
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- LA Davis
- LF Agnati
- LJ Ignarro
- LJ Scott
- LS Winterfield
- M Angehagen
- M Atkins
- M Clozel
- M El Ghachi
- M Foley
- M Garcia-Calvo
- M Goto
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- M Reinsprecht
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- M Sanada
- M Schmidinger
- MA Hooks
- MA Rogawski
- MC McManus
- MC Wolvekamp
- MH Saier Jr
- MH Saier Jr
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- MJ Owens
- MJ Zapor
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- ML Linenberger
- MLAV Heien
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- MR Law
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- NR Goldberg
- NR Goldberg
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- R Morphy
- RA Goodnow Jr
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- RJ Heath
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- RJ Martin
- RK Sylvester
- RM Eglen
- RM Garavito
- RM Goldberg
- RM Greenberg
- RR Ruffolo
- RW Miller
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- S Frantz
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- S Paula
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- SE Hyman
- SM Hecht
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- SN Sehgal
- SP Alexander
- SS Hegde
- T Grosser
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- T Ninomiya
- TC Kwong
- TD Fenn
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- TM Willson
- TR Kleyman
- TS Faber
- U Eckstein-Ludwig
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- V Jendrossek
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- W Gao
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- WB Mattes
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- WL Smith
- WR Kukovetz
- X Li
- Y Huang
- Y Molad
- Y Zhu
- Z Chen
- ZH Siddik
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Ion Implantation
- Author
- A Addamiano
- A Addamiano
- A Andersson
- A Axmann
- A Axmann
- A Balazs
- A Barez
- A Barez
- A Blaha
- A Bontemps
- A Bontemps
- A Brelot
- A Corciovei
- A Corciovei
- A Desalvo
- A Desalvo
- A Desalvo
- A Desalvo
- A Feuerstein
- A Feuerstein
- A Feuerstein
- A Fiderkiewicz
- A Garin
- A Goetzberger
- A Golanski
- A Golanski
- A Golanski
- A Herman
- A Hiraki
- A Hornung
- A Kostka
- A Kostka
- A Kostka
- A Luches
- A Pegoraro
- A Piotrowski
- A Richardt
- A Strojnik
- A Toi
- A Wittkower
- AA Gavrilov
- AA Vlasov
- AA Vlasov
- AB Campbell
- AB Wittkower
- AD Vlasov
- AE Leneva
- AE Michel
- AF Akkerman
- AF Malov
- AG Zajdin
- AH Agajanian
- AH Greenaway
- AH Kachare
- AI Gerasimov
- AK Gnap
- ALM Davies
- AM Ghander
- AN Georgobiani
- AN Saxena
- Anon.
- Anon.
- Anon.
- AP Mamontov
- AP Mamontov
- AP Pathak
- AP Pathak
- AP Pathak
- AR Bayly
- AR Bayly
- AR Hutson
- AS Avakov
- AS Pasyuk
- AT Forrester
- AU MacRae
- AU MacRae
- AV Ryabtsov
- AV Vasilev
- AW Lees
- AW Tinsley
- B Crawford
- B Deveaud
- B Domeij
- B Hofflinge
- B Netange
- B Tell
- BA MacIver
- BA MacIver
- BC Feng
- BG Pettersson
- BI Bondarev
- BI Ivanov
- BI Vikhrev
- BJ Masters
- BJ Masters
- BJ Masters
- BJ Saealy
- BJ Sealy
- BJ Smith
- BK Herbert
- BK Shin
- BK Shin
- BL Crowder
- BL Crowder
- BL Crowder
- BL Crowder
- BL Crowder
- BM Welch
- BT French
- C Allen
- C Foster
- C Huang
- C Jech
- C Legrand
- C Lejeune
- C Lejeune
- C MacDonald
- C Weber
- CA Barile
- CB Fite
- CB Norris
- CB Norris
- CC Mai
- CC Wang
- CD Moak
- CE Hurwitz
- CF Pihl
- CJ Kircher
- CM Hsieh
- CP Wu
- CP Wu
- CR Allen
- CR Fritzsche
- CR Fritzsche
- CR Fritzsche
- CW Perkins
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- W Schemmert
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- W Stumpfi
- W Zenker
- WC Ko
- WC Niehaus
- WD Wilson
- WE Choi
- WF Ohnesorge
- WFJ Frank
- WH Weisenberger
- WJ Anderson
- WJ Evans
- WK Chu
- WK Chu
- WK Chu
- WK Chu
- WK Hofker
- WK Hofker
- WK Hofker
- WK Hofker
- WK Lin
- WK Wu
- WL Brown
- WM Portnoy
- WM Pritchard
- WM Pritchard
- WN Hammer
- WN Hammer
- WS Johnson
- Y Akasaka
- Y Akasaka
- Y Akasaka
- Y Akasaka
- Y Kato
- Y Krylov
- Y Makita
- Y Makita
- Y Makita
- Y Ohmura
- Y Okuyama
- Y Ono
- Y Quere
- Y Quere
- Y Segawa
- Y Shiraki
- Y Wada
- Y Yuba
- Y Zohta
- YG Kozlov
- YH Ohtsuki
- YH Ohtsuki
- YH Ohtsuki
- YM Khirnyi
- YN Shutov
- YS Akimov
- YS Park
- YS Park
- YS Park
- YV Bulgakov
- YV Bulgakov
- YV Bulgakov
- YV Bulgakov
- YV Gorelkinskii
- YV Martynenko
- YZ Akilov
- Z Szmid
- ZC Putney
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1976
- Field of study
Translational research in medication development for nicotine dependence
- Author
- A Holmes
- A Jose Lanca
- A Markou
- AA Harrison
- AC King
- AD Redish
- AG Phillips
- AJ Lanca
- AJ Levine
- AJ Waters
- AL Brody
- AL Brody
- AL Brody
- AL Sharpe
- AM Epstein
- AR Caggiula
- AS Kreibich
- AS Lowe
- AS Rauhut
- AS Rauhut
- AS Rauhut
- AS Villegier
- AW Bruijnzeel
- B Arnold
- B Buisson
- B Forget
- B Le Foll
- BJ Everitt
- BL Carter
- BL Roth
- C Cohen
- C Cohen
- C Fonck
- C Gotti
- C Kornetsky
- C Lee
- C Sanchis-Segura
- C Silagy
- CA Conklin
- CA Conklin
- CA Sannerud
- Caryn Lerman
- CK Funk
- CL Walters
- CL Walters
- CR Maxwell
- CS Pomerleau
- D Borsook
- D Lin
- D McBride
- DA Gorelick
- DF Emerich
- DF Emerich
- DH Malin
- DH Malin
- DH Malin
- DH Malin
- DK Miller
- DL Braff
- DL Due
- DY Kuo
- EC Donny
- EC Donny
- ED Levin
- ED Levin
- EJ Houtsmuller
- EJ Nestler
- EM Sellers
- ES Zakharova
- ET Iwamoto
- G Sutherland
- GC Harris
- GC Harris
- GF Koob
- GR Uhl
- H Gaddnas
- H Rollema
- H Rollema
- H Sahraei
- HC Breiter
- IP Stolerman
- IP Stolerman
- IP Stolerman
- J Chao
- J Chin-Dusting
- J Hughes
- J Phillips
- JA Blendy
- JA Dani
- JA Davis
- JA Kauer
- JB Kamien
- JD Belluzzi
- JD Brioni
- JE Rose
- JE Rose
- JE Rose
- JE Rose
- JE Rose
- JE Rose
- JE Slemmer
- Jennifer A Davis
- JF Cryan
- JL Katz
- JL Rutter
- JL Wiley
- JL Wilkinson
- JM Bossert
- JP McEvoy
- JP Pinel
- JR James
- JS Fowler
- JW Smith
- K Fagerstrom
- K Guillem
- K Guillem
- K Junghanns
- K Lasser
- KA O'Connor
- KA Perkins
- KA Perkins
- KA Perkins
- KA Perkins
- KA Perkins
- KA Perkins
- KA Perkins
- KA Perkins
- KA Perkins
- KA Perkins
- KA Sacco
- Kenneth A. Perkins
- KL Metzger
- L Fattore
- LE O'Dell
- LH Brauer
- LH Brauer
- LJ Bierut
- LJ Van Eldik
- LM Juliano
- LP Dwoskin
- LR Cardon
- M Davis
- M Egli
- M Rukstalis
- M Shoaib
- M Shoaib
- M Shoaib
- M Sofuoglu
- M Zaniewska
- MA Marissen
- MA Nader
- Mark G. LeSage
- ME Wewers
- MF Stromberg
- MG LeSage
- MG LeSage
- MG LeSage
- MG LeSage
- MI Palmatier
- MI Palmatier
- MJ Kreek
- MJ Kreek
- MJ Wright
- ML Bondarev
- MM Bradley
- MM Faraday
- MM Prendergast
- MR Munafo
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- MR Picciotto
- MS Cousins
- MS Cousins
- MT Bardo
- MW Johnson
- N Capriles
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- NA Horenstein
- ND Volkow
- NE Paterson
- NE Paterson
- Neal L. Benowitz
- NH Caskey
- NH Caskey
- NL Benowitz
- P Maurer
- P Olausson
- P Pouletty
- P Vezina
- PJ Fudala
- PJ Kenny
- PJ Kenny
- PJ Kenny
- PN Tobler
- PW Kalivas
- PW Kalivas
- QR Liu
- R Klink
- R Nemeth-Coslett
- R Nemeth-Coslett
- R Nemeth-Coslett
- R Ray
- R Schnoll
- R Sinha
- R Young
- RA Bevins
- RA Wise
- RA Wise
- RD Hurt
- RD Hurt
- RI Desai
- RS Eisenberg
- RS Mansbach
- RZ Goldstein
- S Dawe
- S Erb
- S Semenova
- S Shiffman
- S Shiffman
- S Shiffman
- S Wonnacott
- SA Chen
- SA McKee
- SC Woods
- SD Glick
- SD Glick
- SD Glick
- SD Grabus
- SD Grabus
- SE Hyman
- SE Hyman
- SJ Siegel
- SJ Siegel
- SL Dewey
- SR Goldberg
- SR Laviolette
- SS O'Malley
- SS Watkins
- ST Tiffany
- Stephanie S. O'Malley
- Steven J. Siegel
- SV Mahler
- T Eissenberg
- TA Shahan
- TB Baker
- TE Kippin
- TE Robinson
- TH Brandon
- TJ De Vries
- TJ Gould
- TM Piasecki
- TN Ferraro
- V Teneggi
- VJ DeNoble
- W van den Brink
- WA Corrigall
- WA Corrigall
- WA Corrigall
- WA Corrigall
- WA Corrigall
- WA Corrigall
- WB Pickworth
- William A. Corrigall
- WK Bickel
- WM Chornock
- X Liu
- X Liu
- Y Shaham
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study