2 research outputs found
Unfolded protein response in cancer: the Physician's perspective
- Author
- A So
- AH Lee
- AJWL Dorner
- AN Shajahan
- AS Lee
- AZK Fribley
- BC Cross
- BE Hanson
- BP Gomez
- BQ Liu
- BR Roberto Piva
- C Jamora
- C Jolly
- C Koumenis
- C Sidrauski
- C Xu
- D Dong
- D Ron
- D Ron
- D Scheuner
- DB Solit
- DFaAC Koong
- DG Breckenridge
- DM Townsend
- DP Lu
- DR Carrasco
- DR Fels
- DR McMillan
- DSB Scheuner
- DT WJ Rutkowski
- E Caldas-Lopes
- E Szegezdi
- EA Obeng
- EG Mimnaugh
- EG Mimnaugh
- EI Heath
- EL Davenport
- EL Davenport
- G Velasco
- G Wang
- H Uramoto
- H Yoshida
- H Zinszner
- HC Zheng
- HRTA Park
- J Hoseki
- J Li
- J Matsuo
- J Patterson
- J Ye
- J Ye
- JF San Miguel
- JKR Wu
- JM Backer
- JSO Sterz
- K Lee
- K Mori
- K Shin-Ya
- K Zhang
- Kezhong Zhang
- KKR Zhang
- KPC Travers
- KST Yamamoto
- L Qu
- L Romero-Ramirez
- M Guzman
- M Guzman
- M Kitamura
- M Salazar
- M Shuda
- MG Goldstein
- MKR Schroder
- MP Davies
- MS Song
- N Morishima
- OA O'Connor
- P Heather
- P Lee AFW
- P Pyrko
- P Scriven
- PM Fernandez
- PN Eunjung Lee
- Q Wang
- Q Wang
- R Langer
- RCCD Wek
- RJ Kaufman
- RV Rao
- RV Rao
- S Pacey
- S Saito
- S Sun
- SJ Marciniak
- SSVJL Brodsky
- T Verfaillie
- TNU Yorimitsu
- TYJ Nakagawa
- U Banerji
- W Yan
- Xiaoxin Chen
- Xuemei Li
- Y Fu
- Y Futamura
- Y Ma
- Zihai Li
- Publication venue
- BioMed Central
- Publication date
- 01/01/2011
- Field of study
The unfolded protein response (UPR) is a cascade of intracellular stress signaling events in response to an accumulation of unfolded or misfolded proteins in the lumen of the endoplasmic reticulum (ER). Cancer cells are often exposed to hypoxia, nutrient starvation, oxidative stress and other metabolic dysregulation that cause ER stress and activation of the UPR. Depending on the duration and degree of ER stress, the UPR can provide either survival signals by activating adaptive and antiapoptotic pathways, or death signals by inducing cell death programs. Sustained induction or repression of UPR pharmacologically may thus have beneficial and therapeutic effects against cancer. In this review, we discuss the basic mechanisms of UPR and highlight the importance of UPR in cancer biology. We also update the UPR-targeted cancer therapeutics currently in clinical trials
Blüten- und Fruchtbildung. — Flower and fruit formation
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- A Bajer
- A Batalin
- A Bocchi
- A Brunel
- A Calvert
- A Gandrieau
- A Gandrieau
- A Girard
- A Hecht
- A Kagawa
- A Kobayashi
- A Kovoor
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- A Kovoor
- A Lance
- A Lance
- A Lang
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- A Lang
- A Lang
- A Lang
- A Lang
- A Lang
- A Lang
- A Lang
- A Lang
- A Lang
- A Lang
- A Lang
- A Love
- A Mccomb
- A Millardet
- A Nygren
- A Place
- A Place
- A Potapenko
- A Rich
- A Rosenberghein
- A Shakhov
- A Takimoto
- A Takimoto
- A Takimoto
- A Takimoto
- A Takimoto
- A Takimoto
- A Takimoto
- A Takimoto
- A Takimoto
- A Takimoto
- A Takimoto
- A Takimoto
- A Takimoto
- A Takimoto
- A Takriomo
- A Tschirch
- A Uillaume
- AA Aginyan
- AA Avakyan
- AA Avakyan
- AAL Rutgers
- AC Hulme
- AC Hulme
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- AC Leopold
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- AH Blaauw
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- B Solomon
- B Vazart
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- in yarovizing the embryos of wheat seeds without endosperm. C. R. (Dokl.) Acad
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- L’azione dell’acido gibberellicc sull’ accrescimento caulinare di talune piante erbacee in condizioni esterne controllate
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- PW Zimmerman
- QB Zielinski
- R Best
- R Best
- R Bournu
- R Bournu
- R Bournu
- R Brown
- R Btinsow
- R Buvat
- R Buvat
- R Buxsow
- R Combes
- R Combes
- R Combes
- R David
- R Domal
- R Harder
- R Harder
- R Harder
- R Harder
- R Harder
- R Harder
- R Harder
- R Harder
- R Harder
- R Harder
- R Harder
- R Harder
- R Harder
- R Harder
- R Harder
- R Harder
- R Harder
- R Harder
- R Herich
- R Kandeler
- R Kandeler
- R Knapp
- R Koblet
- R Popham
- R Porteres
- R Stoppel
- R Stoppel
- R Ukrich
- R Ukrich
- R Ukrich
- R Ukrich
- R Ukrich
- R Ukrich
- R Ukrich
- R Ukrich
- R Ukrich
- R Ukrich
- R Ukrich
- R Ukrich
- R Ulrich
- R Ulrich
- R-C Huang
- R. H. Roberts
- RA Popham
- RA Scott
- RA Scott
- RA Wetmore
- Rappaport
- RB Tukey
- RB Withxow
- RB Witnxow
- RB Wrrauow
- RB Wrrhuow
- RC Bean
- RC Huang
- RC Sachar
- RC Sachar
- RC Sachar
- RC Sachar
- RC Sachar
- RE Dorland
- RE Duncan
- RE Duncan
- RE Duncan
- RG Bqtenko
- RG Butenkko
- RG Lincoln
- RG Lincoln
- RG Lincoln
- RG Lincoln
- RG Lincoln
- RG Martin
- RG Thomas
- RG Thomas
- RG Thomas
- RH Roberts
- RH Roberts
- RH Wetmore
- RJ Downs
- RJ Downs
- RJ Weaver
- RJ Weaver
- RJ Weaver
- RJ Weaver
- RJ Weaver
- RJ Weaver
- RJ Weaver
- RJ Weaver
- RM Brooks
- RM Davison
- RM Fulford
- RM Muir
- RM Muir
- RM Sachs
- RM Sachs
- RM Sachs
- RM Sachs
- RM Sachs
- RM Sachs
- RM Zacharius
- RM Zacharius
- RO Erickson
- RO Erickson
- RS Croudrri
- RS Deropp
- RS Lindstrom
- RS Lindstrom
- RS Rabin
- RS Young
- RW Harris
- RW Nixon
- S Emerson
- S Herrmann
- S Imamura
- S Imamura
- S Imamura
- S Imamura
- S Imamura
- S Imamura
- S Imamura
- S Imamura
- S Kiyosawa
- S Matsubara
- S Naxata
- S Rehm
- S Sarkar
- S Satina
- S Satina
- S Shinano
- S Spiegelman
- S Spiegelman
- S Toyama
- S Toyama
- S Wright
- S Yasuda
- S Yasuda
- S-L Lam
- S-L Lam
- Sachar
- SB Hendricks
- SB Hendricks
- SB Hendricks
- SB Hendricks
- SC Chakravarti
- Schmitz
- SH Nakayama
- SH Nakayama
- SH Wittwer
- SH Wittwer
- SH Wittwer
- SH Wittwer
- SH Wittwer
- SH Wittwer
- SH Wittwer
- SH Wrrtwer
- SH Wrrtwer
- SH Wrrtwer
- SH Wrrtwer
- SI Koryuxaeva
- SJ Wellensiek
- SJ Wellensiek
- SJ Wellensiek
- SJ Wellensiek
- SJ Wellensiek
- SJ Wellensiek
- SJ Wellensiek
- SJ Wellensiek
- SJ Werrensieg
- SL Lam
- SM Caplin
- Sosa-Bourdouil C., A. Brunel et A. Sosa
- SP Johnson
- SP Naithani
- Sroehit. H. A.
- SS Nakayama
- SS Nakayama
- SS Nakayama
- SS Nakayama
- SS Pawar
- SS Teaotia
- STC Wright
- STC Wright
- T Egucar
- T Hemberg
- T Hom
- T Inagaei
- T Kanosueoka
- T Loo
- T Saito
- T Saito
- T Schmucker
- T Schmucker
- T Schmucker
- T Sugawara
- T Tamaoki
- T Visser
- T-HT Hsiang
- T-HT Hsiang
- TA Bell
- TAA Nase
- TAA Nase
- TB Mcclelland
- TD Lysenko
- TG Mason
- TG Phillips
- The effect of photoperiodic régime on vernalization of winter wheat
- The influence of leaves and the root system on flower-bud differentiation and growth of seedlings of biennial plants. [Russ.] Dokl
- TR Alexander
- TS Foster
- TV Olejnikova
- TV Olejnikova
- U Clever
- U Neumann
- U Tetley
- V Evreinoff
- V Gregoire
- V Raghavan
- V Raghavan
- VA Greulach
- VA Novixov
- VA Novixov
- VA Tiedjens
- VB Youngner
- VG Allfrey
- VG Grif
- VG Konarev
- VI Razumov
- VI Razumov
- VI Razumov
- VI Razumov
- VI Razumov
- VI Razumov
- VI Razumov
- VN Katunskij
- vThe second report on the behavior of the pollen tubes in the production of seedless fruits caused by interspecific pollination. Jap
- W Engelmann
- W Haurt
- W Haurt
- W Haurt
- W Haurt
- W Haurt
- W Haurt
- W Haurt
- W Heinze
- W Junges
- W Junges
- W Junges
- W Junges
- W Konitz
- W Pfeffer
- W Pfeffer
- W Rauh
- W Runger
- W Runger
- W Runger
- W Runger
- W Runger
- W Runger
- W Runger
- W Seifriz
- W Seifriz
- W Seifriz
- W Seifriz
- W Seifriz
- W Stone
- Walur.Abe E.
- WB Sinclair
- WB Srxclair
- WC Cooper
- WC Galinat
- WC Gregory
- WC Hall
- WC Hall
- WD Bigelow
- WE Martin
- WE Snyder
- WE Snyder
- WG Rosen
- WH Camp
- WH Gbaggs
- WH Powers
- WH Schopfer
- WH Smith
- WJ Lord
- WK Purves
- WL Butler
- WL Woodburn
- WM Bayliss
- WN Dannenburo
- WO Griesel
- WP Jacobs
- WP Jacobs
- WR Tulecke
- WR Tulecke
- WR Tulecke
- WS Hillman
- WS Hillman
- WS Hillman
- WS Hillman
- WS Hillman
- WS Hillman
- WS Hillman
- WS Stewart
- WS Stewart
- WS Stewart
- WS Stewart
- WW Garner
- WW Garner
- WW Schwabe
- WW Schwabe
- WW Schwabe
- WW Schwabe
- WW Schwabe
- WW Schwabe
- WW Schwabe
- WW Schwabe
- WW Schwabe
- WW Schwabe
- Y Hotta
- Y Hotta
- Y Iwanami
- Y Kato
- Y Murakami
- Y Murakami
- Y Murakami
- Y Ogawa
- Y Ogawa
- Y Ogawa
- Y Ogawa
- Y Ogawa
- Y Tashima
- Y Tashima
- Y Tashima
- Y Tashima
- Y Tsukamoto
- Y Tsukamoto
- Y Tsukamoto
- Y Tsukamoto
- Y Tsukamoto
- Y Tsukamoto
- Z Kasai
- ZM Shvedskaya
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1965
- Field of study