9 research outputs found

    Student Learning Experience and Student Retention Strategies: A Transformative Approach to Quality Education

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    The Sustainable Development Goals (SDGs) on quality education emphasizes that reducing disparities and inequalities related to the provision of primary, secondary, and tertiary education. Generally, the higher education institutions are using both business and corporate-level strategies to reach out to face-to-face, blended, and online learning students. Against this backdrop, this study argues that to increase student retention rates in the higher education institutions, and provide higher education that enables individuals to become lifelong learners, the following retention strategies can be implemented– (1) Academic Support Programs, (2) Provision of Capable Resources, (3) high quality of instruction delivery, (4) Provision of scholarships and subsidizing higher education fees

    Systematic review with meta-analysis of the epidemiological evidence relating FEV<sub>1</sub> decline to lung cancer risk

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    <p>Abstract</p> <p>Background</p> <p>Reduced FEV<sub>1</sub> is known to predict increased lung cancer risk, but previous reviews are limited. To quantify this relationship more precisely, and study heterogeneity, we derived estimates of β for the relationship RR(diff) = exp(βdiff), where diff is the reduction in FEV<sub>1</sub> expressed as a percentage of predicted (FEV<sub>1</sub>%P) and RR(diff) the associated relative risk. We used results reported directly as β, and as grouped levels of RR in terms of FEV<sub>1</sub>%P and of associated measures (e.g. FEV<sub>1</sub>/FVC).</p> <p>Methods</p> <p>Papers describing cohort studies involving at least three years follow-up which recorded FEV<sub>1</sub> at baseline and presented results relating lung cancer to FEV<sub>1</sub> or associated measures were sought from Medline and other sources. Data were recorded on study design and quality and, for each data block identified, on details of the results, including population characteristics, adjustment factors, lung function measure, and analysis type. Regression estimates were converted to β estimates where appropriate. For results reported by grouped levels, we used the NHANES III dataset to estimate mean FEV<sub>1</sub>%P values for each level, regardless of the measure used, then derived β using regression analysis which accounted for non-independence of the RR estimates. Goodness-of-fit was tested by comparing observed and predicted lung cancer cases for each level. Inverse-variance weighted meta-analysis allowed derivation of overall β estimates and testing for heterogeneity by factors including sex, age, location, timing, duration, study quality, smoking adjustment, measure of FEV<sub>1</sub> reported, and inverse-variance weight of β.</p> <p>Results</p> <p>Thirty-three publications satisfying the inclusion/exclusion criteria were identified, seven being rejected as not allowing estimation of β. The remaining 26 described 22 distinct studies, from which 32 independent β estimates were derived. Goodness-of-fit was satisfactory, and exp(β), the RR increase per one unit FEV<sub>1</sub>%P decrease, was estimated as 1.019 (95%CI 1.016-1.021). The estimates were quite consistent (I<sup>2</sup> =29.6%). Mean age was the only independent source of heterogeneity, exp(β) being higher for age <50 years (1.024, 1.020-1.028).</p> <p>Conclusions</p> <p>Although the source papers present results in various ways, complicating meta-analysis, they are very consistent. A decrease in FEV<sub>1</sub>%P of 10% is associated with a 20% (95%CI 17%-23%) increase in lung cancer risk.</p

    Use of Tiotropium Bromide for Pre-operative Treatment in Chronic Obstructive Pulmonary Disease Patients: Comparison with Oxitropium Bromide

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    Chronic obstructive pulmonary disease (COPD): Evaluation from clinical, immunological and bacterial pathogenesis perspectives

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    HIV-1 Integrase Inhibitors: A Comparative Review of Efficacy and Safety

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    Maternal and neonatal outcomes after caesarean delivery in the African Surgical Outcomes Study: a 7-day prospective observational cohort study.

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    BACKGROUND: Maternal and neonatal mortality is high in Africa, but few large, prospective studies have been done to investigate the risk factors associated with these poor maternal and neonatal outcomes. METHODS: A 7-day, international, prospective, observational cohort study was done in patients having caesarean delivery in 183 hospitals across 22 countries in Africa. The inclusion criteria were all consecutive patients (aged ≥18 years) admitted to participating centres having elective and non-elective caesarean delivery during the 7-day study cohort period. To ensure a representative sample, each hospital had to provide data for 90% of the eligible patients during the recruitment week. The primary outcome was in-hospital maternal mortality and complications, which were assessed by local investigators. The study was registered on the South African National Health Research Database, number KZ_2015RP7_22, and on ClinicalTrials.gov, number NCT03044899. FINDINGS: Between February, 2016, and May, 2016, 3792 patients were recruited from hospitals across Africa. 3685 were included in the postoperative complications analysis (107 missing data) and 3684 were included in the maternal mortality analysis (108 missing data). These hospitals had a combined number of specialist surgeons, obstetricians, and anaesthetists totalling 0·7 per 100 000 population (IQR 0·2-2·0). Maternal mortality was 20 (0·5%) of 3684 patients (95% CI 0·3-0·8). Complications occurred in 633 (17·4%) of 3636 mothers (16·2-18·6), which were predominantly severe intraoperative and postoperative bleeding (136 [3·8%] of 3612 mothers). Maternal mortality was independently associated with a preoperative presentation of placenta praevia, placental abruption, ruptured uterus, antepartum haemorrhage (odds ratio 4·47 [95% CI 1·46-13·65]), and perioperative severe obstetric haemorrhage (5·87 [1·99-17·34]) or anaesthesia complications (11·47 (1·20-109·20]). Neonatal mortality was 153 (4·4%) of 3506 infants (95% CI 3·7-5·0). INTERPRETATION: Maternal mortality after caesarean delivery in Africa is 50 times higher than that of high-income countries and is driven by peripartum haemorrhage and anaesthesia complications. Neonatal mortality is double the global average. Early identification and appropriate management of mothers at risk of peripartum haemorrhage might improve maternal and neonatal outcomes in Africa. FUNDING: Medical Research Council of South Africa.Medical Research Council of South Africa
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