Detecting and managing patients with type 2 diabetic kidney disease: Proteinuria and cardiovascular disease:Proteinuria and cardiovascular disease

Detecting and managing patients with type 2 diabetic kidney disease: Proteinuria and cardiovascular disease.BackgroundThe increasing prevalence of type 2 diabetes (T2DM) places more patients at risk for developing chronic kidney disease (CKD) or cardiovascular (CV) events. Effective therapy for CKD or CV disease (CVD) requires a method of identifying affected patients and monitoring the effectiveness of therapy.MethodsWe tested the predictive value of proteinuria for identifying patients at risk for progressive CDK and CVD, and monitoring treatment was determined using RENAAL study results.ResultsBaseline proteinuria identified patients at risk for progressive CKD and CVD. Suppression of proteinuria was associated with decreased likelihood of CKD or CVD.ConclusionProteinuria identifies the risk of CKD and CVD, and can be used to monitor the effectiveness of therapy