Distributions of biogeochemical parameters in the pool and interstitial waters in sand bar system of the Kizu River

Distributions of biogeochemical parameters in temporary pools (TAMARI), riparian side arm of river (WANDO) and interstitial waters were investigated in the sand bars along the lower reaches of the Kizu River. Dissloved inorganic nitrogen (DIN) and phosphate (DIP) concentrations in TAMARI and WANDO waters varied greatly compared with those in river waters. Low concentrations of DIN and DIP were often observed simultaneously in TAMARI waters. The DIN concentrations of most intersitial waters were similar or high in comparison to those of river waters. Low concentrations of DIN and DIP were often observed separately in intersitial waters. Concentrations of biogeochemical constituents clearly varied greatly in the waters of sand bar systems, and the relationships between each biogeochemical constituents were different between surface water (TAMARI and WANDO) and subsurface (intersitial) waters of the Kizu River.Article信州大学山地水環境教育研究センター研究報告 2: 63-67(2004)departmental bulletin pape

トルコの湖底柱状堆積物における、古気候変動の指標物質 : 高分子脂肪酸の変化

A 5 m sediment core taken from Lake Kestel in southwestern Anatolia, Turkey, was analyzed for high molecular saturated fatty acids (≧C20 FAs) as a paleoclimatic indicator.In the present paper, we discussed the correlation between the fluctuations in ≧C20 FA concentrations and precipitation in Anatolia over the last 2,000 years based on previous pollen records. The discussion led to the following conclusion:1) The amounts of precipitation about 1,800 to 1,300 years ago were extremely low leading to very dry climatic conditions.2) From 1,300 to 600 years ago, the precipitation increased gradually to a level similar to that of the present with some fluctuations into very low precipitation. From about 600 years ago to the recent past, a wet climate had prevailed.3) From 200 to 40 years ago, the precipitation temporarily increased to about 1.5 times its previous level. Thereafter, it tended to decrease considerably

Basic limnological study in an alpine Lake Puma Yumco, the pre-Himalayas, China

Lake Puma Yumco is a typical alpine lake (altitude; 5,030m) located in the pre-Himalayas of Tibet, China. This study was the first limnologicak investigation. Puma Yumco (28°34'N,90°24'E) has the following morphometric properties: maximum length of 31 km; maximum width of 14 km; mean width of 9 km; shoreline of 90 km; surface area of 280 km²; shoreline development of 1.5. Transparency was approximately 10 m. Dissolved oxygen was l7 mg O₂ L⁻¹ and showed saturated values. Saljnity was 360 mg L⁻¹. The chemical type of the lake water was Mg-Ca-HCO₃-SO₄. Total nitrogenous nutrients and phosphate were extremely low at 1μM and 0.02 μM, respetively. Chlorophyll-a concentration was 0.2 mg chl.a m⁻³. Phytoplankton and zooplankton were dominated by Aphanocapsa. and Diaptomidae. The grain size of lake sediment was that of silt in most cases.Article信州大学山地水環境教育研究センター研究報告 2: 83-90(2004)departmental bulletin pape

Dynamics of dissolved and bubbled methane in Lake Youngrang and HwaJlnPO, Korea

Article信州大学山地水環境教育研究センター研究報告 6: 69-72(2010)departmental bulletin pape

Clinical characteristics and visual outcomes of work-related open globe injuries in Japanese patients

Purpose: To investigate the clinical characteristics and visual outcomes of patients with work-related open globe injuries (OGIs) and compare them with patients with non-work-related OGIs. Design: Retrospective, observational, multicentre, case-control study. Methods: A total of 374 patients with work-related OGIs and 170 patients with non-work-related OGIs who presented to hospitals that belong to the Japan-Clinical Research of Study group from 2005 to 2015 were included in this study. Clinical data including age, sex, initial and final visual acuity, type of open globe injury, lens status, zone of injury, wound length, and presence of proliferative vitreoretinopathy, retinal detachment, expulsive haemorrhage, and endophthalmitis were recorded. Main Outcome Measures: Visual acuity. Results Work-related OGIs were associated with younger age, male sex, better initial and final visual acuity, more laceration, smaller wounds, presence of retinal detachment, and expulsive haemorrhage, compared with non-work-related OGIs. Multiple regression analysis revealed that final visual acuity is significantly associated with initial visual acuity, wound length, and the presence of proliferative vitreoretinopathy in work-related OGIs. Conclusions: Work-related OGIs showed better visual outcomes than other OGIs. Initial visual acuity, wound length, and the presence of proliferative vitreoretinopathy are predictors of visual outcomes in patients with work-related OGIs

Clinical preferences for DME in Japan

Aims/Introduction: To determine the current clinical preferences of anti‐vascular endothelial growth factor (VEGF) treatment protocols for diabetic macular edema (DME) in Japan. Materials and Methods: This was a descriptive cross‐sectional study. Answers to a questionnaire consisting of 16 questions were obtained from 176 of 278 (63.3%) surveyed ophthalmologists. Results: The results showed that 81.2% preferred intravitreal injections of anti‐VEGF antibodies as the first‐line therapy. The most important indicators for beginning anti‐VEGF therapy were: the best‐corrected visual acuity in 44.3% and the retinal thickness in 30.7%. In the loading phase, 53.4% preferred a single injection, and in the maintenance phase, 75.0% preferred the pro re nata regimen. Financial limitation (85.8%) was reported as the most important difficulty in the treatment. For combination therapy with anti‐VEGF treatment, panretinal photocoagulation, focal photocoagulations and a sub‐Tenon steroid injection were preferred. The contraindications for anti‐VEGF therapy were: prior cerebral infarction (72.7%). Regarding the use of both approved anti‐VEGF agents in Japan, ranibizumab and aflibercept, 39.8% doctors used them appropriately. Conclusions: Our results present the current clinical preferences of anti‐VEGF treatment for DME in Japan. The best‐corrected visual acuity and the retinal thickness are important indicators to institute this therapy. The majority of the ophthalmologists use anti‐VEGF treatment as first‐line therapy and prefer the 1 + pro re nata regimen

Diabetic macular edema and aging

Aims/Introduction: In older patients, the management of diabetic macular edema (DME) can be complicated by comorbidities, geriatric syndrome, and socioeconomic status. This study aims to evaluate the effects of aging on the management of DME. Materials and Methods: This is a real-world clinical study including 1,552 patients with treatment-naïve center-involved DME. The patients were categorized into 4 categories by age at baseline (C1, <55; C2, 55–64; C3, 65–74; and C4, ≥75 years). The outcomes were the change in logarithm of the minimum angle of resolution best-corrected visual acuity (logMAR BCVA) and central retinal thickness (CRT), and the number of treatments from baseline to 2 years. Results: From baseline to 2 years, the mean changes in logMAR BCVA from baseline to 2 years were −0.01 in C1, −0.06 in C2, −0.07 in C3, and 0.01 in C4 (P = 0.016), and the mean changes in CRT were −136.2 μm in C1, −108.8 μm in C2, −100.6 μm in C3, and −89.5 μm in C4 (P = 0.008). Treatments applied in the 2 year period exhibited decreasing trends with increasing age category on the number of intravitreal injections of anti-VEGF agents (P = 0.06), selecting local corticosteroid injection (P = 0.031), vitrectomy (P < 0.001), and laser photocoagulation outside the great vascular arcade (P < 0.001). Conclusions: Compared with younger patients with DME, patients with DME aged ≥75 years showed less frequent treatment, a lower BCVA gain, and a smaller CRT decrease. The management and visual outcome in older patients with DME would be unsatisfactory in real-world clinical practice