Attitudes toward immigrants: a cross-country perspective

This paper examines the foundations of attitudes towards immigrants by focusing on individual characteristics and country-specific effects. We use a micro-level data set from 31 countries. In particular, we utilize the module on National Identity of the 2003 International Social Survey Program (ISSP). Results indicate that gender, education, age, labor-market status, and political and religious affiliation are important indicators of the attitude toward immigrants. The largest effect appears to be that of education, with more education being positively correlated with a positive view of immigrants. Additionally, we find that country of residence matters.immigration, microeconomic behavior, comparative research.

Monocyte-endothelial cell interactions in the regulation of vascular sprouting and liver regeneration in mouse

Background & Aims Regeneration of the hepatic mass is crucial to liver repair. Proliferation of hepatic parenchyma is intimately dependent on angiogenesis and resident macrophage-derived cytokines. However the role of circulating monocyte interactions in vascular and hepatic regeneration is not well-defined. We investigated the role of these interactions in regeneration in the presence and absence of intact monocyte adhesion. Methods Partial hepatectomy was performed in wild-type mice and those lacking the monocyte adhesion molecule CD11b. Vascular architecture, angiogenesis and macrophage location were analyzed in the whole livers using simultaneous angiography and macrophage staining with fluorescent multiphoton microscopy. Monocyte adhesion molecule expression and sprouting-related pathways were evaluated. Results Resident macrophages (Kupffer cells) did not migrate to interact with vessels whereas infiltrating monocytes were found adjacent to sprouting points. Infiltrated monocytes colocalized with Wnt5a, angiopoietin 1 and Notch-1 in contact points and commensurate with phosphorylation and disruption of VE-cadherin. Mice deficient in CD11b showed a severe reduction in angiogenesis, liver mass regeneration and survival following partial hepatectomy, and developed unstable and leaky vessels that eventually produced an aberrant hepatic vascular network and Kupffer cell distribution. Conclusions Direct vascular interactions of infiltrating monocytes are required for an ordered vascular growth and liver regeneration. These outcomes provide insight into hepatic repair and new strategies for hepatic regeneration.National Institutes of Health (U.S.) (Grant R01 GM 49039

Implantation of healthy matrix-embedded endothelial cells rescues dysfunctional endothelium and ischaemic tissue in liver engraftment

Objective: Liver transplantation is limited by ischaemic injury which promotes endothelial cell and hepatocyte dysfunction and eventually organ failure. We sought to understand how endothelial state determines liver recovery after hepatectomy and engraftment. Design: Matrix-embedded endothelial cells (MEECs) with retained healthy phenotype or control acellular matrices were implanted in direct contact with the remaining median lobe of donor mice undergoing partial hepatectomy (70%), or in the interface between the remaining median lobe and an autograft or isograft from the left lobe in hepatectomised recipient mice. Hepatic vascular architecture, DNA fragmentation and apoptosis in the median lobe and grafts, serum markers of liver damage and phenotype of macrophage and lymphocyte subsets in the liver after engraftment were analysed 7 days post-op. Results: Healthy MEECs create a functional vascular splice in donor and recipient liver after 70% hepatectomy in mouse protecting these livers from ischaemic injury, hepatic congestion and inflammation. Macrophages recruited adjacent to the vascular nodes into the implants switched to an anti-inflammatory and regenerative profile M2. MEECs improved liver function and the rate of liver regeneration and prevented apoptosis in donor liver lobes, autologous grafts and syngeneic engraftment. Conclusions: Implants with healthy endothelial cells rescue liver donor and recipient endothelium and parenchyma from ischaemic injury after major hepatectomy and engraftment. This study highlights endothelial-hepatocyte crosstalk in hepatic repair and provides a promising new approach to improve regenerative medicine outcomes and liver transplantation

Nitrogen management.

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Late-time tails, entropy aspects, and stability of black holes with anisotropic fluids

In this work we consider black holes surrounded by anisotropic fluids in four dimensions. We first study the causal structure of these solutions showing some similarities and differences with Reissner-Nordstr\"om-de Sitter black holes. In addition, we consider scalar perturbations on this background geometry and compute the corresponding quasinormal modes. Moreover, we discuss the late-time behavior of the perturbations finding an interesting new feature, i.e., the presence of a subdominant power-law tail term. Likewise, we compute the Bekenstein entropy bound and the first semiclassical correction to the black hole entropy using the brick wall method, showing their universality. Finally, we also discuss the thermodynamical stability of the model.Comment: 23 pages, 4 figure

The consequences of early childhood growth failure over the life course:

This paper examines the impact over the life course of early childhood growth failure as measured by achieved height at 36 months. It uses data collected on individuals who participated in a nutritional supplementation trial between 1969 and 1977 in rural Guatemala and who were subsequently reinterviewed between 2002 and 2004. It finds that individuals who did not suffer growth failure in the first three years of life complete more schooling, score higher on tests of cognitive skill in adulthood, have better outcomes in the marriage market, earn higher wages and are more likely to be employed in higher-paying skilled labor and white-collar jobs, are less likely to live in poor households, and, for women, fewer pregnancies and smaller risk of miscarriages and stillbirths. Growth failure has adverse impacts on body size and several dimensions of physical fitness in adulthood but does not have marked effects on risk indicators of cardiovascular and related chronic diseases. These results provide a powerful rationale for investments that reduce early-life growth failure.Chronic disease, early life growth failure, fertility, Human capital, Poverty, Undernutrition, Wages,

Fusion of SPOT5 multispectral and Ikonos panchromatic images

International audienceThe offer of high spectral and high spatial resolutions images has grown in the last decade. It is know possible to obtain data from different sources with different spatial and spec-tral resolutions. The field of data fusion of remotely sensed data grown also very fast in the last years. In this paper, an algorithm allowing the merging of SPOT 5 images and Ikonos images are proposed. This algorithm is based on the ARSIS concept and presents an implementation for a ratio of spatial resolution equal to 10. The ARSIS concept is first detailed. Then, the way of de-fining a new implementation based on this concept is presented, allowing to understand how to define new implementations and to develop new solutions based on this concept. The proposed algorithm is developed, describing the different steps for building a fused product from a SPOT 5 multispectral data at 10 m and from a IKONOS panchromatic data at 1 m. Some other methods are proposed. The evaluation of the quality of the different methods is achieved using a set of quantitative quality parameters. The visual quality of the products are evaluated by a set of inter-preters. Conclusions are drawn on the quality of the proposed products