Genetic susceptibility to Candida infection: A new look at an old entity

In recent years, several studies have shed light on the pathogenesis of many novel immune defects associated with narrow susceptibility to bacterial, viral and fungal infections. Genetically determined forms of susceptibility to Candida species infection, which had been elusive for a long time, have been recognized. Refractory or recurrent infections of skin, nails and the mucous membranes are clinical signs of chronic mucocutaneous candidiasis, frequently associated with immunological defects in the Th17 subset, which is crucial for host response against infections at mucosal and epithelial sites. Here we review the main clinical features and the mechanisms of diseases which share CMC as main phenotype

Analysis of the impact of length of stay on the quality of service experience, satisfaction and loyalty

Although length of stay is a relevant variable in destination management, little research has been produced connecting it with tourists' post-consumption behaviour. This research compares the post-consumption behaviour of same-day visitors with overnight tourists in a sample of 398 domestic vacationers at two Mediterranean heritage-and-beach destinations. Although economic research on length of stay posits that there are destination benefits in longer stays, same-day visitors score higher in most of the post-consumption variables under study. Significant differences arise in hedonic aspects of the tourist experience and destination loyalty. Thus, we propose that length of stay can be used as a segmentation variable. Furthermore, destination management organisations need to consider length of stay when designing tourism policies. The tourist product and communication strategies might be adapted to different vacation durations

Personal space, extraversion, anxiety and personal perception

The aim of the present research is to explore the relationship among two personality factors (extraversion-introversion and anxiety),personal perception and personal space in a condition of low acquain tance.A sample of 5) female university students,who had a low degree of familiarity wih one another,were considered.~he subjects were asked to choose out of the research sample four mates and to place each of them on a modified form of the Comfortable InterPersonal Distance Scale. ~hen each sUbject-rated himself and the four mates by a questionnaire on actual and ideal extraversion and on actual and ideal anxiety.A weak later the subjects completed the MPI.On the base of the CID neasures 44 near mates and 57 distant mates were seuared.On the same base were also separed the corresponding subjects ,'rhoplaced their mates "near" from those ~lho ulaced them "far" .The statistica..1.com parison showed a eeneral desirability ofextraversion ~~d low anxiety both as personal traits and as social traits~However, the major results support only partially the hypothesis that the perceived desirability of a trai t affects personal space also when subjects are not familiar with one another