12 research outputs found
‘Latent’ Portal Hypertension in Benign Biliary Obstruction
A prospective study was undertaken to evaluate the changes in portal venous pressure in patients with
benign biliary obstruction (BBO) but without overt clinical, endoscopic or radiological evidence of portal
hypertension. Portal venous pressure was measured at laparotomy in 20 patients (10 each with either
benign biliary stricture or choledocholithiasis) before and after biliary decompression. Pressure was found
to be on the high side in seven patients (>25 cm of saline in three patients and > 30 cm of saline in four).
The mean fall of pressure was 3.4 cm of saline after biliary decompression. No correlation could, however,
be found between portal venous pressure and duration of biliary obstruction, serum bilirubin or bile duct
pressure. Liver histology showed mild to moderate cholestatic changes but maintained portal architecture
in all. Benign biliary obstruction may therefore, lead to elevation of portal pressure, even though the
patient may not necessarily have any clinical, endoscopic or radiological manifestations of portal hypertension.
The pathogenesis of this ‘latent’ portal hypertension is probably multifactorial. If biliary obstruction
is left untreated the development of overt portal hypertension may become a possibility in the future
Amebic Liver Abscess With Intra-Biliary Rupture
The case of a large amebic liver abscess with an atypical presentation is reported. High output bile
drainage persisted after ultrasound guided percutaneous catheter drainage because of a preexisting
communication of the abscess with the right hepatic ductal system. The abscess was managed
successfully by surgical evacuation and internal drainage into a defunctioned jejunal loop
Partial Cholecystectomy Safe and Effective
Patients undergoing surgical treatment for calculous disease were considered to have had a partial
cholecystectomy performed when a part of the gall bladder wall was retained for technical reasons.
Forty patients underwent partial cholecystectomy: for chronic cholecystitis (20), acute cholecystitis (4),
Mirizzi's syndrome (14), portal hypertension or partially accesible gall bladder (one patient each). Four
patients (10%) developed infective complications and two patients had retained common bile duct
stones. In a mean follow up period of 13 months (range 1–36 mths), only 3 patients have ongoing mild
dyspeptic symptoms while the rest have remained asymptomatic. Partial cholecystectomy has been
found to be a safe and effective procedure in difficult cholecystectomy situations, since it combines the
merits of cholecystectomy and cholecystostomy