13 research outputs found
Blue economy discourses and practices: reconfiguring ocean spaces in the Philippines
© 2020, Springer-Verlag GmbH Germany, part of Springer Nature. Blue economy initiatives have emerged along marine and coastal areas, seeking to bring the green economy into a ‘blue world’. Often defined as a global policy agenda, blue economy discourses and practices aim to generate ‘blue growth’ by linking poverty reduction, social equality, and marine conservation. While global and national policies have spent decades addressing coastal resource management, broader blue economy discourses and practices seem, on the surface, to promote economic growth strategies for marine conservation. Increasingly, new market-oriented programs and projects aim to tap the financial value of the ocean’s ‘blue capital’, ostensibly fostering income generation and sustainable solutions for conservation finance. Drawing on critical discourse analysis and key-informant interviews across scales, we examine the meanings and practices of the blue economy in Southeast Asia and in the Philippines. As an archipelagic nation, millions of coastal dwellers in the Philippines depend on oceans as a major source of livelihood, food security, and well-being. We examine how multilateral institutions, bilateral organisations, state agencies, civil society organisations, and other key actors represent and enact the blue economy discursively and in practice. We find that oceans are being imagined as an open frontier that must be managed and utilised for both conservation and economic purposes. New territorialisation processes are creating new borders and management structures that often bypass social and environmental safeguards, posing a major threat to coastal dwellers. We conclude that by foregrounding economic development and coastal management, more socially just and environmentally sustainable governance approaches are neglected
Transient Nature of Long-Term Nonprogression and Broad Virus-Specific Proliferative T-Cell Responses with Sustained Thymic Output in HIV-1 Controllers
HIV-1(+) individuals who, without therapy, conserve cellular anti-HIV-1 responses, present with high, stable CD4(+) T-cell numbers, and control viral replication, facilitate analysis of atypical viro-immunopathology. In the absence of universal definition, immune function in such HIV controllers remains an indication of non-progression.CD4 T-cell responses to a number of HIV-1 proteins and peptide pools were assessed by IFN-gamma ELISpot and lymphoproliferative assays in HIV controllers and chronic progressors. Thymic output was assessed by sjTRECs levels. Follow-up of 41 HIV-1(+) individuals originally identified as "Long-term non-progressors" in 1996 according to clinical criteria, and longitudinal analysis of two HIV controllers over 22 years, was also performed. HIV controllers exhibited substantial IFN-gamma producing and proliferative HIV-1-specific CD4 T-cell responses to both recombinant proteins and peptide pools of Tat, Rev, Nef, Gag and Env, demonstrating functional processing and presentation. Conversely, HIV-specific T-cell responses were limited to IFN-gamma production in chronic progressors. Additionally, thymic output was approximately 19 fold higher in HIV controllers than in age-matched chronic progressors. Follow-up of 41 HIV-1(+) patients identified as LTNP in 1996 revealed the transitory characteristics of this status. IFN-gamma production and proliferative T-cell function also declines in 2 HIV controllers over 22 years.Although increased thymic output and anti-HIV-1 T-cell responses are observed in HIV controllers compared to chronic progressors, the nature of nonprogressor/controller status appears to be transitory
Decreased level of recent thymic emigrants in CD4+ and CD8+T cells from CML patients
<p>Abstract</p> <p>Background</p> <p>T-cell immunodeficiency is a common feature in cancer patients, which may relate to initiation and development of tumor. Based on our previous finding, to further characterize the immune status, T cell proliferative history was analyzed in CD4+ and CD8+ T cells from chronic myeloid leukemia (CML) patients.</p> <p>Methods</p> <p>Quantitative analysis of δRec-ψJα signal joint T cell receptor excision circles (sjTRECs) was performed in PBMCs, CD3+, CD4+ and CD8+T cells by real-time PCR, and the analysis of 23 <it>TRBV-D1 </it>sjTRECs was performed by semi-nested PCR. Forty eight CML cases in chronic phase (CML-CP) were selected for this study and 17 healthy individuals served as controls.</p> <p>Results</p> <p>The levels of δRec-ψJα sjTRECs in PBMCs, CD3+, CD4+, and CD8+ T cells were significantly decreased in CML patients, compared with control groups. Moreover, the numbers of detectable <it>TRBV </it>subfamily sjTRECs, as well as the frequency of particular <it>TRBV-BD</it>1 sjTRECs in patients with CML were significantly lower than those from healthy individuals.</p> <p>Conclusions</p> <p>We observed decreased levels of recent thymic emigrants in CD4+ and CD8+ T cells that may underlay the persistent immunodeficiency in CML patients.</p
Fish, Trade and Food Security: Moving beyond ‘Availability’ Discourse in Marine Conservation
© 2016, Springer Science+Business Media New York. The goal of food security increasingly serves as an objective and justification for marine conservation in the global south. In the marine conservation literature this potential link is seldom based upon detailed analysis of the socioeconomic pathways between fish and food security, is often based on limited assumptions about increasing the availability of fish stocks, and downplays the role of trade. Yet, the relationship between fish and food security is multi-faceted and complex, with various local contextual factors that mediate between fish and food security. We use data from interviews and food security assessment methods to examine the relationship between fish and food security among fishing households in San Vicente, Palawan province, Philippines. We highlight the local role of income and trade, emphasising the sale of fish to purchase food not easily accessible for fishers, particularly staples. In particular, we show that because rice is the primary staple of food security for these households, fish must be traded with the intent of buying rice. Trade is therefore central to household food security. We argue that the relationship between fish and food security must be considered in greater depth if marine conservation is to engage with food security as an objective
Moving beyond financial value in seafood commodity chains
© 2018 Elsevier Ltd Emerging forms of governance and many academic analyses of seafood commodity chains currently have a strong focus on financial value, transmitted in a linear ‘vertical’ fashion from fisher, through traders to eventual consumers. This Brief Communication argues that the social dimensions of value must be given explicit attention in analysis if seafood commodity chains are to be made more equitable and sustainable in changing governance contexts. The paper draws on evidence from selected seafood commodity chains across the Philippines, demonstrating the range of co-produced social values that are of equal or greater significance than financial value. Fishers, traders and consumers, all generate multiple social values that shape the nature and outcomes of seafood commodity chains. In contrast to forms of fisheries governance that focus exclusively on financial or ecological values, the paper suggests that integrating multiple social values into the governance of seafood commodity chains, as well as at the site of production, should become a core focus of research and policy
Coastal transitions: Small-scale fisheries, livelihoods, and maritime zone developments in Southeast Asia
Across Southeast Asia, coastal livelihoods are becoming more diverse and more commodified, as maritime zone developments intensify. We review literature from the ten maritime states in Southeast Asia to assess how older and emerging forms of maritime zone developments influence the viability of small-scale fishing livelihoods. Applying a political economy lens to small-scale fisheries and maritime zone developments at regional scale, we show how small-scale fisheries persist as a significant coastal livelihood activity across the region, despite declining opportunities due to long-term intensification of fisheries exploitation. The paper further analyses the ways in which newer maritime zone developments, including aquaculture, land reclamation, special industrial zones, and tourism interact with fishing, and are reconfiguring coastal livelihoods in the region. Key trends that small-scale fishers and coastal communities must negotiate include deepening commodification, worsening environmental degradation, loss of access to fishing grounds, and an intensifying ‘squeeze’ on coastal space
Fish, Trade and Food Security: Moving beyond ‘Availability’ Discourse in Marine Conservation
The goal of food security increasingly serves as an objective and justification for marine conservation in the global south. In the marine conservation literature this potential link is seldom based upon detailed analysis of the socioeconomic pathways between fish and food security, is often based on limited assumptions about increasing the availability of fish stocks, and downplays the role of trade. Yet, the relationship between fish and food security is multi-faceted and complex, with various local contextual factors that mediate between fish and food security. We use data from interviews and food security assessment methods to examine the relationship between fish and food security among fishing households in San Vicente, Palawan province, Philippines. We highlight the local role of income and trade, emphasising the sale of fish to purchase food not easily accessible for fishers, particularly staples. In particular, we show that because rice is the primary staple of food security for these households, fish must be traded with the intent of buying rice. Trade is therefore central to household food security. We argue that the relationship between fish and food security must be considered in greater depth if marine conservation is to engage with food security as an objective