Zika virus infection in pregnancy: a protocol for the joint analysis of the prospective cohort studies of the ZIKAlliance, ZikaPLAN and ZIKAction consortia

INTRODUCTION: Zika virus (ZIKV) infection in pregnancy has been associated with microcephaly and severe neurological damage to the fetus. Our aim is to document the risks of adverse pregnancy and birth outcomes and the prevalence of laboratory markers of congenital infection in deliveries to women experiencing ZIKV infection during pregnancy, using data from European Commission-funded prospective cohort studies in 20 centres in 11 countries across Latin America and the Caribbean. METHODS AND ANALYSIS: We will carry out a centre-by-centre analysis of the risks of adverse pregnancy and birth outcomes, comparing women with confirmed and suspected ZIKV infection in pregnancy to those with no evidence of infection in pregnancy. We will document the proportion of deliveries in which laboratory markers of congenital infection were present. Finally, we will investigate the associations of trimester of maternal infection in pregnancy, presence or absence of maternal symptoms of acute ZIKV infection and previous flavivirus infections with adverse outcomes and with markers of congenital infection. Centre-specific estimates will be pooled using a two-stage approach. ETHICS AND DISSEMINATION: Ethical approval was obtained at each centre. Findings will be presented at international conferences and published in peer-reviewed open access journals and discussed with local public health officials and representatives of the national Ministries of Health, Pan American Health Organization and WHO involved with ZIKV prevention and control activities

Novas espécies e notas sobre Cerambycidae (Coleoptera) do Pará e do nordeste do Brasil New species and notes on Cerambycidae (Coleoptera) from Pará and Brazilian norteastern

<abstract language="eng">Based on material collected by P. Jauffert in Pará and by L. Ianuzzi in Alagoas and Sergipe, four new species are described: Temnopis fasciata sp. nov. (Oemini) and Dihammaphoroides jaufferti sp. nov. (Cleomenini) from Pará. This species breads in branches of Pseudopiptadenia suaveolens (Miq.) J. W. Grimes, Fabaceae. Adetus tuberosus sp. nov. (Apomecynini) and Mimasyngenes lucianae sp. nov. (Desmiphorini) from Alagoas. New records and notes are provided for Neocompsa serrana (Martins, 1962) and Rhopalophora occipitalis Chevrolat, 1859