6,574 research outputs found

    Symmetries of the ratchet current

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    Recent advances in nonequilibrium statistical mechanics shed new light on the ratchet effect. The ratchet motion can thus be understood in terms of symmetry (breaking) considerations. We introduce an additional symmetry operation besides time-reversal, that effectively reverses the nonequilibrium driving. That operation of field-reversal combined with time-reversal decomposes the nonequilibrium action so to clarify under what circumstances the ratchet current is a second order effect around equilibrium, what is the direction of the ratchet current and what are possibly the symmetries in its fluctuations.Comment: 13 pages, heavily extended versio

    Heat bounds and the blowtorch theorem

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    We study driven systems with possible population inversion and we give optimal bounds on the relative occupations in terms of released heat. A precise meaning to Landauer's blowtorch theorem (1975) is obtained stating that nonequilibrium occupations are essentially modified by kinetic effects. Towards very low temperatures we apply a Freidlin-Wentzel type analysis for continuous time Markov jump processes. It leads to a definition of dominant states in terms of both heat and escape rates.Comment: 11 pages; v2: minor changes, 1 reference adde

    Amplification of compressional MHD waves in systems with forced entropy oscillations

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    The propagation of compressional MHD waves is studied for an externally driven system. It is assumed that the combined action of the external sources and sinks of the entropy results in the harmonic oscillation of the entropy (and temperature) in the system. It is found that with the appropriate resonant conditions fast and slow waves get amplified due to the phenomenon of parametric resonance. Besides, it is shown that the considered waves are mutually coupled as a consequence of the nonequilibrium state of the background medium. The coupling is strongest when the plasma β1\beta \approx 1. The proposed formalism is sufficiently general and can be applied for many dynamical systems, both under terrestrial and astrophysical conditions.Comment: 14 pages, 4 figures, Accepted to Physical Review

    Dynamical fluctuations for semi-Markov processes

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    We develop an Onsager-Machlup-type theory for nonequilibrium semi-Markov processes. Our main result is an exact large time asymptotics for the joint probability of the occupation times and the currents in the system, establishing some generic large deviation structures. We discuss in detail how the nonequilibrium driving and the non-exponential waiting time distribution influence the occupation-current statistics. The violation of the Markov condition is reflected in the emergence of a new type of nonlocality in the fluctuations. Explicit solutions are obtained for some examples of driven random walks on the ring.Comment: Minor changes, accepted for publication in Journal of Physics

    Malignancy Following Renal Transplantation

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    Non-equilibrium stationary state of a two-temperature spin chain

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    A kinetic one-dimensional Ising model is coupled to two heat baths, such that spins at even (odd) lattice sites experience a temperature TeT_{e} (% T_{o}). Spin flips occur with Glauber-type rates generalised to the case of two temperatures. Driven by the temperature differential, the spin chain settles into a non-equilibrium steady state which corresponds to the stationary solution of a master equation. We construct a perturbation expansion of this master equation in terms of the temperature difference and compute explicitly the first two corrections to the equilibrium Boltzmann distribution. The key result is the emergence of additional spin operators in the steady state, increasing in spatial range and order of spin products. We comment on the violation of detailed balance and entropy production in the steady state.Comment: 11 pages, 1 figure, Revte

    Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways

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    It is of considerable translational importance whether depression is a form or a consequence of sickness behavior. Sickness behavior is a behavioral complex induced by infections and immune trauma and mediated by pro-inflammatory cytokines. It is an adaptive response that enhances recovery by conserving energy to combat acute inflammation. There are considerable phenomenological similarities between sickness behavior and depression, for example, behavioral inhibition, anorexia and weight loss, and melancholic (anhedonia), physio-somatic (fatigue, hyperalgesia, malaise), anxiety and neurocognitive symptoms. In clinical depression, however, a transition occurs to sensitization of immuno-inflammatory pathways, progressive damage by oxidative and nitrosative stress to lipids, proteins, and DNA, and autoimmune responses directed against self-epitopes. The latter mechanisms are the substrate of a neuroprogressive process, whereby multiple depressive episodes cause neural tissue damage and consequent functional and cognitive sequelae. Thus, shared immuno-inflammatory pathways underpin the physiology of sickness behavior and the pathophysiology of clinical depression explaining their partially overlapping phenomenology. Inflammation may provoke a Janus-faced response with a good, acute side, generating protective inflammation through sickness behavior and a bad, chronic side, for example, clinical depression, a lifelong disorder with positive feedback loops between (neuro)inflammation and (neuro)degenerative processes following less well defined triggers

    A meaningful expansion around detailed balance

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    We consider Markovian dynamics modeling open mesoscopic systems which are driven away from detailed balance by a nonconservative force. A systematic expansion is obtained of the stationary distribution around an equilibrium reference, in orders of the nonequilibrium forcing. The first order around equilibrium has been known since the work of McLennan (1959), and involves the transient irreversible entropy flux. The expansion generalizes the McLennan formula to higher orders, complementing the entropy flux with the dynamical activity. The latter is more kinetic than thermodynamic and is a possible realization of Landauer's insight (1975) that, for nonequilibrium, the relative occupation of states also depends on the noise along possible escape routes. In that way nonlinear response around equilibrium can be meaningfully discussed in terms of two main quantities only, the entropy flux and the dynamical activity. The expansion makes mathematical sense as shown in the simplest cases from exponential ergodicity.Comment: 19 page

    An outbreak of sheep-associated malignant catarrhal fever in sows

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    his paper describes a case of malignant catarrhal fever in a sow herd in Belgium caused by infection with ovine herpesvirus-2 (OHV-2). The 11 affected sows had high fever and 10 of them died within 3 days after the onset of clinical disease. The most prominent macroscopic lesion was a hemorrhagic to pseudo-membranous gastritis. Histopathology revealed severe infiltration and necrosis of the gastric mucosa. Neither antimicrobial treatment nor injection with anti-inflammatory drugs ameliorated the severity of the disease. As the sows and sheep were housed in the same building with the possibility of having direct nose-to-nose contact, and as PCR testing showed that the virus found in the sows was identical to that found in the sheep, it is very likely that the infection was transmitted from the subclinically infected sheep to the sows. The present case showed that OHV-2 infection should be included in the differential diagnosis when facing problems of fever followed by death, especially when pigs are housed in close contact with sheep
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