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ここでは,先ず規制緩和の内容や消費生活に影響するものを一般論として整理をした。次に,アンケート調査に基づく分析を行い,規制緩和に対する理解度をみたが,全体的に規制緩和が家庭生活に及ぼす影響については認識しているようであった。しかし,具体的な項目別での理解度は,生活に密着している規制緩和は理解度が高いが,それ以外になると非常に低い結果が出た。それ故,行政担当者は一般消費者により理解が出来るような広報を考え,理解した上での実行でないとトラブルが出てくると思われる。また規制緩和の社会的問題点についても,外国からの圧力というデメリット部分の認識が強く,今後規制緩和を推進していく上で行政担当者はメリット・デメリットを充分消費者に理解して貰えるような,広報を考える必要がある。さらに,規制緩和問題から見た消費者の要望・期待はあまり大きくないが,その中で,(1)物価問題,(2)景気対策,(3)消費者の要望を取り入れる機関,(4)外国製品の輸入拡大等々にあることが分かった。今後,規制緩和は時代的流れではあるが,国民の生活安全保護や企業・国家の発展等の面から,最低限の規制は残すべきである。また,消費者に対して物を見る目を養わせると同時に,生活面の保護を受ける権利の自覚を持たせるようにするため,消費者教育を強く進める必要がある。なお,第2報で消費者のメリット・デメリットと要望を分析するが,それらを基に,統括して行政・企業・消費者への『課題と提言』をしたい

Hepatic reactive lymphoid hyperplasia in a patient with primary biliary cirrhosis

Reactive lymphoid hyperplasia (RLH) of the liver is an extremely rare lesion characterized by the proliferation of non-neoplastic lymphocytes forming follicles. Hepatic RLH is known to be associated with gastrointestinal carcinoma and autoimmune diseases including primary biliary cirrhosis (PBC). We report a case of hepatic RLH in a patient with PBC and gastric cancer. A 68 year old Japanese woman with a 10 year history of liver enzyme abnormality was admitted. Laboratory testing revealed that her anti-mitochondrial antibody was markedly elevated. Five mo after the diagnosis of PBC, she was found to have gastric cancer. Abdominal computed tomography disclosed a liver nodule in S8, suggesting metastatic gastric carcinoma. Histopathologically, the resected liver lesion comprised of a nodular proliferation of small lymphocytes with lymphoid follicles. This is the first reported case of hepatic RLH in a patient with both PBC and gastric cancer. Pre-operative diagnosis of hepatic RLH by clinical imaging is extremely difficult. Therefore, a needle biopsy could be useful to make a diagnosis of hepatic RLH, especially to differentiate from metastatic gastrointestinal carcinoma

Hepatocellular carcinoma occurring in a Crohn’s disease patient

We report a case of hepatocellular carcinoma (HCC) occurring in a patient with Crohn’s disease (CD) without chronic hepatitis or liver cirrhosis, and review the clinicopathological features of HCC in CD patients. A 37-year-old Japanese man with an 8-year history of CD and a medication history of azathioprine underwent resection of a liver tumor. The histopathology of the liver tumor was pseudoglandular type HCC. In the non-neoplastic liver, focal hepatocyte glycogenosis (FHG) was observed, however, there was no evidence of liver cirrhosis or primary sclerosing cholangitis. Only nine cases of HCC in CD patients have been reported previously in the English-language literature. Eight of 10 cases (including the present case) had received azathioprine treatment, and four of these cases also showed FHG, which is considered a preneoplastic liver lesion, within the non-neoplastic liver. Although the precise mechanism of the development of HCC in CD patients is controversial, these results suggest that azathioprine therapy and FHG in the non-neoplastic liver contribute to the development of HCC. These findings also indicate that it is important to survey CD patients treated with prolonged azathioprine therapy for potential liver tumors