Clinical Science Unique risks for mortality in patients with end-stage renal disease undergoing nonemergent colorectal surgery

Abstract BACKGROUND: The aim of this study was to identify unique risk factors for mortality in patients with end-stage renal disease undergoing nonemergent colorectal surgery. METHODS: A multivariate logistic regression model predicting 30-day mortality was constructed for patients with end-stage renal disease undergoing nonemergent colorectal procedures. Data were obtained from the National Surgical Quality Improvement Program (2005Program ( -2010. RESULTS: Among the 394 patients analyzed, those with serum creatinine levels .7.5 mg/dL had .07 times the adjusted mortality risk of those with levels ,3.5 mg/dL. For colorectal surgery patients, the average serum creatinine level was 5.52 6 2.6 mg/dL, and mortality was 13% (n 5 50). CONCLUSIONS: High serum creatinine was associated with a lower risk for mortality in patients with end-stage renal disease, even though creatinine is often considered a risk factor for surgery. These results show how variables from a patient-centered subpopulation can differ in meaning from the general population. 4 This database is a tool that records perioperative risk factors for addressing surgical morbidity and mortality. Our objective was to use the NSQIP data to create a multivariate model to identify unique risk factors predicting mortality in patients with ESRD undergoing nonemergent colorectal procedures