Stability Walls in Heterotic Theories

We study the sub-structure of the heterotic Kahler moduli space due to the presence of non-Abelian internal gauge fields from the perspective of the four-dimensional effective theory. Internal gauge fields can be supersymmetric in some regions of the Kahler moduli space but break supersymmetry in others. In the context of the four-dimensional theory, we investigate what happens when the Kahler moduli are changed from the supersymmetric to the non-supersymmetric region. Our results provide a low-energy description of supersymmetry breaking by internal gauge fields as well as a physical picture for the mathematical notion of bundle stability. Specifically, we find that at the transition between the two regions an additional anomalous U(1) symmetry appears under which some of the states in the low-energy theory acquire charges. We compute the associated D-term contribution to the four-dimensional potential which contains a Kahler-moduli dependent Fayet-Iliopoulos term and contributions from the charged states. We show that this D-term correctly reproduces the expected physics. Several mathematical conclusions concerning vector bundle stability are drawn from our arguments. We also discuss possible physical applications of our results to heterotic model building and moduli stabilization.Comment: 37 pages, 4 figure

Heterotic Compactification, An Algorithmic Approach

We approach string phenomenology from the perspective of computational algebraic geometry, by providing new and efficient techniques for proving stability and calculating particle spectra in heterotic compactifications. This is done in the context of complete intersection Calabi-Yau manifolds in a single projective space where we classify positive monad bundles. Using a combination of analytic methods and computer algebra we prove stability for all such bundles and compute the complete particle spectrum, including gauge singlets. In particular, we find that the number of anti-generations vanishes for all our bundles and that the spectrum is manifestly moduli-dependent.Comment: 36 pages, Late

Publisher Correction: Reflections and projections on a decade of climate science (Nature Climate Change, (2021), 11, 4, (279-285), 10.1038/s41558-021-01020-x)

Published: 14 June 202

Effect of cross-linked biodegradable polymers on sustained release of sodium diclofenac-loaded microspheres

The objective of this study was to formulate an oral sustained release delivery system of sodium diclofenac(DS) based on sodium alginate (SA) as a hydrophilic carrier in combination with chitosan (CH) and sodium carboxymethyl cellulose (SCMC) as drug release modifiers to overcome the drug-related adverse effects and to improve bioavailability. Microspheres of DS were prepared using an easy method of ionotropic gelation. The prepared beads were evaluated for mean particle size, entrapment efficiency, swelling capacity, erosion and in-vitro drug release. They were also subjected to various studies such as Fourier Transform Infra-Red Spectroscopy (FTIR) for drug polymer compatibility, Scanning Electron Microscopy for surface morphology, X-ray Powder Diffraction Analysis (XRD) and Differential Scanning Calorimetric Analysis (DSC) to determine the physical state of the drug in the beads. The addition of SCMC during the preparation of polymeric beads resulted in lower drug loading and prolonged release of the DS. The release profile of batches F5 and F6 showed a maximum drug release of 96.97 ± 0.356% after 8 h, in which drug polymer ratio was decreased. The microspheres of sodium diclofenac with the polymers were formulated successfully. Analysis of the release profiles showed that the data corresponds to the diffusion-controlled mechanism as suggested by Higuchi

A Statistical Study of Galactic SNRs using the PMN Survey

The Parkes-MIT-NRAO (PMN) radio survey has been used to generate a quasi all-sky study of Galactic Supernova Remnants (SNRs) at a common frequency of 4.85 GHz. We present flux densities estimated for the sample of 110 Southern Galactic SNRs (up to Dec = - 65 deg.) observed with the Parkes 64-m radio telescope and an additional sample of 54 from the Northern PMN (up to Dec = +64 deg.) survey undertaken with the Green Bank 43-m (20 SNRs) and 91-m (34 SNRs) radio telescopes. Out of this total sample of 164 selected SNRs (representing 71% of the 231 known SNRs in the Green catalogue) we consider 138 to provide reliable estimates of flux density and surface brightness distribution. This sub-sample represents those SNRs which fall within carefully chosen selection criteria which minimises the effects of the known problems in establishing reliable fluxes from the PMN survey data. Our selection criteria are based on a judicious restriction of source angular size and telescope beam together with careful evaluation of fluxes on a case by case basis. This gives confidence in the newly derived PMN fluxes when the selection criteria are respected. We find a sharp drop off in the flux densities for Galactic SNRs beyond 4 Jy and then a fairly flat distribution from 5-9 Jy, a slight decline and a further flat distribution from 9-20 Jy though the numbers of SNR in each Jy bin are low. We also re-visit the contentious Sigma-D relation to determine a new power law index for a sub-sample of shell type SNRs which yields beta= -2.2 +/- 0.6. This new evaluation of the Sigma-D relation, applied to the restricted sample, provides new distance estimates and their Galactic scale height distribution. We find a peak in the SNR distribution between 7-11 kpc with most restricted to +/- 100 pc Galactic scale height.Comment: 14 pages, 7 figures. Accepted for publishing in Astrophysics and Space Scienc

The Theory of Brown Dwarfs and Extrasolar Giant Planets

Straddling the traditional realms of the planets and the stars, objects below the edge of the main sequence have such unique properties, and are being discovered in such quantities, that one can rightly claim that a new field at the interface of planetary science and and astronomy is being born. In this review, we explore the essential elements of the theory of brown dwarfs and giant planets, as well as of the new spectroscopic classes L and T. To this end, we describe their evolution, spectra, atmospheric compositions, chemistry, physics, and nuclear phases and explain the basic systematics of substellar-mass objects across three orders of magnitude in both mass and age and a factor of 30 in effective temperature. Moreover, we discuss the distinctive features of those extrasolar giant planets that are irradiated by a central primary, in particular their reflection spectra, albedos, and transits. Aspects of the latest theory of Jupiter and Saturn are also presented. Throughout, we highlight the effects of condensates, clouds, molecular abundances, and molecular/atomic opacities in brown dwarf and giant planet atmospheres and summarize the resulting spectral diagnostics. Where possible, the theory is put in its current observational context.Comment: 67 pages (including 36 figures), RMP RevTeX LaTeX, accepted for publication in the Reviews of Modern Physics. 30 figures are color. Most of the figures are in GIF format to reduce the overall size. The full version with figures can also be found at: http://jupiter.as.arizona.edu/~burrows/papers/rm

History of clinical transplantation

How transplantation came to be a clinical discipline can be pieced together by perusing two volumes of reminiscences collected by Paul I. Terasaki in 1991-1992 from many of the persons who were directly involved. One volume was devoted to the discovery of the major histocompatibility complex (MHC), with particular reference to the human leukocyte antigens (HLAs) that are widely used today for tissue matching.1 The other focused on milestones in the development of clinical transplantation.2 All the contributions described in both volumes can be traced back in one way or other to the demonstration in the mid-1940s by Peter Brian Medawar that the rejection of allografts is an immunological phenomenon.3,4 © 2008 Springer New York

Depth Of Maximum Of Air-shower Profiles At The Pierre Auger Observatory. I. Measurements At Energies Above 1017.8ev

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