Disentangling the effects of early caregiving experience and heritable factors on brain white matter development in rhesus monkeys

Early social experiences, particularly maternal care, shape behavioral and physiological development in primates. Thus, it is not surprising that adverse caregiving, such as child maltreatment leads to a vast array of poor developmental outcomes, including increased risk for psychopathology across the lifespan. Studies of the underlying neurobiology of this risk have identified structural and functional alterations in cortico-limbic brain circuits that seem particularly sensitive to these early adverse experiences and are associated with anxiety and affective disorders. However, it is not understood how these neurobiological alterations unfold during development as it is very difficult to study these early phases in humans, where the effects of maltreatment experience cannot be disentangled from heritable traits. The current study examined the specific effects of experience (“nurture”)versus heritable factors (“nature”)on the development of brain white matter (WM)tracts with putative roles in socioemotional behavior in primates from birth through the juvenile period. For this we used a randomized crossfostering experimental design in a naturalistic rhesus monkey model of infant maltreatment, where infant monkeys were randomly assigned at birth to either a mother with a history of maltreating her infants, or a competent mother. Using a longitudinal diffusion tensor imaging (DTI)atlas-based tract-profile approach we identified widespread, but also specific, maturational changes on major brain tracts, as well as alterations in a measure of WM integrity (fractional anisotropy, FA)in the middle longitudinal fasciculus (MdLF)and the inferior longitudinal fasciculus (ILF), of maltreated animals, suggesting decreased structural integrity in these tracts due to early adverse experience. Exploratory voxelwise analyses confirmed the tract-based approach, finding additional effects of early adversity, biological mother, social dominance rank, and sex in other WM tracts. These results suggest tract-specific effects of postnatal maternal care experience versus heritable or biological factors on primate WM microstructural development. Further studies are needed to determine the specific behavioral outcomes and biological mechanisms associated with these alterations in WM integrity

Nonlinear screening and percolative transition in a two-dimensional electron liquid

A novel variational method is proposed for calculating the percolation threshold, the real-space structure, and the thermodynamical compressibility of a disordered two-dimensional electron liquid. Its high accuracy is verified against prior numerical results and newly derived exact asymptotics. The inverse compressibility is shown to have a strongly asymmetric minimum at a density that is approximately the triple of the percolation threshold. This implies that the experimentally observed metal-insulator transition takes place well before the percolation point is reached.Comment: 4 pages, 2 figures. (v2) minor changes (v3) reference added (v4) few more references adde

Refluxed rice husk ash/NaOH suspension for preparing alkali activated binders

Geopolymers simultaneously containing two waste materials have been developed: fluid catalytic cracking catalyst (FCC) as mineral admixture and rice husk ash (RHA) for preparing an alkaline activator. Alkaline activators were prepared by refluxing aqueous mixtures of ground or original RHA with NaOH. All mortars with alkaline activator containing RHA show compressive strength (cured at 65 °C for 1 day) in the range of 31 41 MPa, which is similar to control mortar prepared using an equivalent mixture of NaOH and water glass. Refluxing times between 30 and 240 min yielded good performance mortars. This new way of valorisation would imply economic and environmental benefits in geopolymer production.GEOCEDEM Project BIA 2011-26947 was financed by Spanish Government, Project 3018/2009 was financed by Generalitat Valenciana, Project AP/35235/11 was financed by AECID, COMBURES Project was financed by Centro de Cooperacion al Desarrollo de la Universitat Politecnica de Valencia ADSIDEO COOPERACIO and OMYA Clariana S.A. and Maicerias Espanolas DACSA S.A. supplied FCC and RHA samples respectively.Bouzón, N.; Paya Bernabeu, JJ.; Borrachero Rosado, MV.; Soriano Martínez, L.; Mitsuuchi Tashima, M.; Monzó Balbuena, JM. (2014). Refluxed rice husk ash/NaOH suspension for preparing alkali activated binders. Materials Letters. 115:72-74. https://doi.org/10.1016/j.matlet.2013.10.001S727411

Temperature Variation of Ultra Slow Light in a Cold Gas

A model is developed to explain the temperature dependence of the group velocity as observed in the experiments of Hau et al (Nature {\bf397}, 594 (1999)). The group velocity is quite sensitive to the change in the spatial density. The inhomogeneity in the density and its temperature dependence are primarily responsible for the observed behavior.Comment: 12 pages, 4 figure

Current Status of the Resonant Spin-Flavor Precession Solution to the Solar Neutrino Problem

We discuss the current status of the resonant spin-flavor precession (RSFP) solution to the solar neutrino problem. We perform a fit to all the latest solar neutrino data for various assumed magnetic field profiles in the sun. We show that the RSFP can account for all the solar neutrino experiments, giving as good fit as other alternative solutions such as MSW or Just so, and therefore can be a viable solution to the solar neutrino problemComment: RevTex file, 9 pages, 12 postscript figures, Some errors are corrected, some changes in results but no change in conclusions, version to appear in Astroparticle Physic

Effective DBHF Method for Asymmetric Nuclear Matter and Finite Nuclei

A new decomposition of the Dirac structure of nucleon self-energies in the Dirac Brueckner-Hartree-Fock (DBHF) approach is adopted to investigate the equation of state for asymmetric nuclear matter. The effective coupling constants of $\sigma$, $\omega$, $\delta$ and $\rho$ mesons with a density dependence in the relativistic mean field approach are deduced by reproducing the nucleon self-energy resulting from the DBHF at each density for symmetric and asymmetric nuclear matter. With these couplings the properties of finite nuclei are investigated. The agreement of charge radii and binding energies of finite nuclei with the experimental data are improved simultaneously in comparison with the projection method. It seems that the properties of finite nuclei are sensitive to the scheme used for the DBHF self-energy extraction. We may conclude that the properties of the asymmetric nuclear matter and finite nuclei could be well described by the new decomposition approach of the G matrix.Comment: 16 pages, 5 figure

A new geopolymeric binder from hydrated-carbonated cement

This paper evaluates the use of hydrated Portland cement as the raw material in the production of geopolymers. The silicon and aluminium oxides needed for the geopolymerization process were produced by the carbonation of hydrated Portland cement, which transforms CSH and CAH (Portland cement hydrates) into silica and alumina gels. Hydrated-carbonated Portland cement was alkali activated with a NaOH/waterglass solution. Pastes and mortars were prepared, and micro-structural and mechanical properties were analyzed. It has been noted that geopolymers are mechanically stable and yield compressive strength higher than 10 MPa when mortars are cured at 65 °C for 3 days. The results have shown that there are interesting possibilities for re-using the cement-rich fraction of construction and demolition waste. Alkaline activation of hydrated-carbonated Portland cement could be considered a low CO 2-emission binder. © 2012 Elsevier B.V. All rights reserved.Paya Bernabeu, JJ.; Borrachero Rosado, MV.; Monzó Balbuena, JM.; Soriano Martinez, L.; Mitsuuchi Tashima, M. (2012). A new geopolymeric binder from hydrated-carbonated cement. Materials Letters. 74:223-225. doi:10.1016/j.matlet.2012.01.132S2232257

Nitrogen and Iron Availability Drive Metabolic Remodeling and Natural Selection of Diverse Phytoplankton during Experimental Upwelling

Nearly half of carbon fixation and primary production originates from marine phytoplankton, and much of it occurs in episodic blooms in upwelling regimes. Here, we simulated blooms limited by nitrogen and iron by incubating Monterey Bay surface waters with subnutricline waters and inorganic nutrients and measured the wholecommunity transcriptomic response during mid- and late-bloom conditions. Cell counts revealed that centric and pennate diatoms (largely Pseudo-nitzschia and Chaetoceros spp.) were the major blooming taxa, but dinoflagellates, prasinophytes, and prymnesiophytes also increased. Viral mRNA significantly increased in late bloom and likely played a role in the bloom\u27s demise. We observed conserved shifts in the genetic similarity of phytoplankton populations to cultivated strains, indicating adaptive population-level changes in community composition. Additionally, the density of single nucleotide variants (SNVs) declined in late-bloom samples for most taxa, indicating a loss of intraspecific diversity as a result of competition and a selective sweep of adaptive alleles. We noted differences between mid- and late-bloom metabolism and differential regulation of light-harvesting complexes (LHCs) under nutrient stress. While most LHCs are diminished under nutrient stress, we showed that diverse taxa upregulated specialized, energy-dissipating LHCs in low iron. We also suggest the relative expression of NRT2 compared to the expression of GSII as a marker of cellular nitrogen status and the relative expression of iron starvationinduced protein genes (ISIP1, ISIP2, and ISIP3) compared to the expression of the thiamine biosynthesis gene (thiC) as a marker of iron status in natural diatom communities

Electrical transport studies of quench condensed Bi films at the initial stage of film growth: Structural transition and the possible formation of electron droplets

The electrical transport properties of amorphous Bi films prepared by sequential quench deposition have been studied in situ. A superconductor-insulator (S-I) transition was observed as the film was made increasingly thicker, consistent with previous studies. Unexpected behavior was found at the initial stage of film growth, a regime not explored in detail prior to the present work. As the temperature was lowered, a positive temperature coefficient of resistance (dR/dT > 0) emerged, with the resistance reaching a minimum before the dR/dT became negative again. This behavior was accompanied by a non-linear and asymmetric I-V characteristic. As the film became thicker, conventional variable-range hopping (VRH) was recovered. We attribute the observed crossover in the electrical transport properties to an amorphous to granular structural transition. The positive dR/dT found in the amorphous phase of Bi formed at the initial stage of film growth was qualitatively explained by the formation of metallic droplets within the electron glass.Comment: 7 pages, 6 figure

Alkali activated materials based on fluid catalytic cracking catalyst residue (FCC): Influence ofSiO2/Na2O and H2O/FCC ratio on mechanical strength and microstructure

Reuse of industrial and agricultural wastes as supplementary cementitious materials (SCMs) in concrete and mortar productions contribute to sustainable development. In this context, fluid catalytic cracking catalyst residue (spent FCC), a byproduct from the petroleum industry and petrol refineries, have been studied as SCM in blended Portland cement in the last years. Nevertheless, another environmental friendly alternative has been conducted in order to produce alternative binders with low CO2 emissions. The use of aluminosilicate materials in the production of alkali-activated materials (AAMs) is an on going research topic which can present low CO2 emissions associated. Hence, this paper studies some variables that can influence the production of AAM based on spent FCC. Specifically, the influence of SiO2/Na2O molar ratio and the H2O/spent FCC mass ratio on the mechanical strength and microstructure are assessed. Some instrumental techniques, such as SEM, XRD, pH and electrical conductivity measurements, and MIP are performed in order to assess the microstructure of formed alkali-activated binder. Alkali activated mortars with compressive strength up to 80 MPa can be formed after curing for 3 days at 65 C. The research demonstrates the potential of spent FCC to produce alkali-activated cements and the importance of SiO2/Na2O molar ratio and the H2O/spent FCC mass ratio in optimising properties and microstructure.Authors would like to thank to the Ministerio de Ciencia e Innovacion (MICINN) of the Spanish Government (BIA2011-26947) and to FEDER for funding, and also to the PROPG - UNESP "Universidade Estadual Paulista Julio de Mesquita Filho'', Brazil.Mitsuuchi Tashima, M.; Akasaki, JL.; Melges, J.; Soriano Martínez, L.; Monzó Balbuena, JM.; Paya Bernabeu, JJ.; Borrachero Rosado, MV. (2013). Alkali activated materials based on fluid catalytic cracking catalyst residue (FCC): Influence ofSiO2/Na2O and H2O/FCC ratio on mechanical strength and microstructure. Fuel. 108:833-839. https://doi.org/10.1016/j.fuel.2013.02.052S83383910