7 research outputs found

    Effect of Spray Directions on the Crystal Growth of Fluorine-Doped Tin Oxide One-dimensional nanostructured Thin Films

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    In this study the novel spray pyrolysis technique, known as rotational, pulsed and atomized spray deposition method was used to fabricate vertically aligned and well separated FTO One-dimensional nanostructures on glass substrate. It was confirmed that spraying at low angle to the substrate is mandatory for the crystal growth of vertically aligned nanorods. The preferential orientation of nanorods crystallites along the (101) direction and prepared nanorods thin film showed an excellent transparency of 84.8% and a low resistance of 26.7 Ω/sq

    Doxorubicin loaded magnesium oxide nanoflakes as ph dependent carriers for simultaneous treatment of cancer and hypomagnesemia

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    © 2019 by the authors. Licensee MDPI, Basel, Switzerland. Doxorubicin (DOX) is an anticancer drug commonly used in treating cancer; however, it has severe cytotoxicity effects. To overcome both the adverse effects of the drug and mineral deficiency (i.e., hypomagnesemia) experienced by cancer patients, we have developed magnesium oxide (MgO) nanoflakes as drug carriers and loaded them with DOX for use as a targeted drug delivery (TDD) system for potential application in cancer therapy. The synthesis employed herein affords pure, highly porous MgO nanoparticles that are void of the potentially harmful metal contaminants often discussed in the literature. Purposed for dual therapy, the nanoparticles exhibit an impressive 90% drug loading capacity with pH dependent drug releasing rates of 10% at pH 7.2, 50.5% at pH 5.0, and 90.2% at pH 3. Results indicate that therapy is achievable via slow diffusion where MgO nanoflakes degrade (i.e., dissolve) under acidic conditions releasing the drug and magnesium ions to the cancerous region. The TDD system therefore minimizes cytotoxicity to healthy cells while supplying magnesium ions to overcome hypomagnesemia

    Rosa rugosa Thunb. ex Murray

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    Rosa rugosa Thunb. ex Murray

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