Mechanism of Nickel and Chromium-Induced Immunotoxicity and Oxidative Stress: A Comparative Study

Abstract Introduction: Chromium (Cr) and Nickel (Ni) are examples of commonly used industrial substances with negative long time exposure on human health. One mechanism whereby metals can alter health is through modulation of immune homeostasis. They are capable of producing oxidative stress and it is possible that this oxidative stress contributes to the carcinogenic response of these metals