41,648 research outputs found
Recent Trends in Hospitalization for Acute Myocardial Infarction in Beijing: Increasing Overall Burden and a Transition From ST-Segment Elevation to Non-ST-Segment Elevation Myocardial Infarction in a Population-Based Study
Comparable data on trends of hospitalization rates for ST-segment elevation myocardial infarction (STEMI) and non-STEMI (NSTEMI) remain unavailable in representative Asian populations.To examine the temporal trends of hospitalization for acute myocardial infarction (AMI) and its subtypes in Beijing.Patients hospitalized for AMI in Beijing from January 1, 2007 to December 31, 2012 were identified from the validated Hospital Discharge Information System. Trends in hospitalization rates, in-hospital mortality, length of stay (LOS), and hospitalization costs were analyzed by regression models for total AMI and for STEMI and NSTEMI separately. In total, 77,943 patients were admitted for AMI in Beijing during the 6 years, among whom 67.5% were males and 62.4% had STEMI. During the period, the rate of AMI hospitalization per 100,000 population increased by 31.2% (from 55.8 to 73.3 per 100,000 population) after age standardization, with a slight decrease in STEMI but a 3-fold increase in NSTEMI. The ratio of STEMI to NSTEMI decreased dramatically from 6.5:1.0 to 1.3:1.0. The age-standardized in-hospital mortality decreased from 11.2% to 8.6%, with a significant decreasing trend evident for STEMI in males and females (P < 0.001) and for NSTEMI in males (P = 0.02). The rate of percutaneous coronary intervention increased from 28.7% to 55.6% among STEMI patients. The total cost for AMI hospitalization increased by 56.8% after adjusting for inflation, although the LOS decreased by 1 day.The hospitalization burden for AMI has been increasing in Beijing with a transition from STEMI to NSTEMI. Diverse temporal trends in AMI subtypes from the unselected "real-world" data in Beijing may help to guide the management of AMI in China and other developing countries
3D quantum Hall effect of Fermi arcs in topological semimetals
The quantum Hall effect is usually observed in 2D systems. We show that the
Fermi arcs can give rise to a distinctive 3D quantum Hall effect in topological
semimetals. Because of the topological constraint, the Fermi arc at a single
surface has an open Fermi surface, which cannot host the quantum Hall effect.
Via a "wormhole" tunneling assisted by the Weyl nodes, the Fermi arcs at
opposite surfaces can form a complete Fermi loop and support the quantum Hall
effect. The edge states of the Fermi arcs show a unique 3D distribution, giving
an example of (d-2)-dimensional boundary states. This is distinctly different
from the surface-state quantum Hall effect from a single surface of topological
insulator. As the Fermi energy sweeps through the Weyl nodes, the sheet Hall
conductivity evolves from the 1/B dependence to quantized plateaus at the Weyl
nodes. This behavior can be realized by tuning gate voltages in a slab of
topological semimetal, such as the TaAs family, CdAs, or NaBi. This
work will be instructive not only for searching transport signatures of the
Fermi arcs but also for exploring novel electron gases in other topological
phases of matter.Comment: 5 pages, 3 figure
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