103 research outputs found

    Methods of Research of Shape Memory Effect and Superelasticity in the Alloy Ti-22%Nb-6%Zr

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    Cyclic tensile tests were carried out as applied to annealed foils of the superelastic Ti-22Nb-6Zr alloy (at.%) as well as indentation of these foils with an increasing amplitude of indenter intrusion in the sample at temperatures lowering from 20∘ down to -60-70∘C. Mechanical tests were performed on samples cut along andacross the rolling direction. According to the results of measurements of mechanical properties, it is established that during cyclic stretching of foils in the rolling direction, superelasticity manifests itself, and also material training is observed with subsequent preservation of the maximal renewable deformation. When the foil is loaded in the transverse direction, no superelasticity is observed, moreover, some samplesare destroyed even with a deformation of 2%. With a decrease in the annealing temperature of foils, the curve of the continuous change of loading with the depth of indenter penetration undergoes substantial changes, which indicate the appearance of a superelastic deformation under the indenter. Curves of monotonic loading and discharge undergo an inflection, and the plastic deformation region is substantially reduced. From the discharge curves in this case, we can calculate two elastic modules, typical for the usual elasticity and superelastic behavior of the alloy. In general, the main characteristics of the continuous indentation curve depend on the amount of the martensitic phase. The dependence of the modules of elasticity for foils, coolingdown to -(60-70∘C), and for their subsequent heating up to the room temperature is constructed

    Regularities of Changes in Structure and Texture of Low Modulus Alloy Zr-25Nb at Cold Rolling of Monocrystals with Different Orientations

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    The paper presents the results of studying the regularities of formation of the rolling texture in single crystals of Zr-25%Nb alloy, with different initial orientation relative to the external principal directions in the sheet: normal (ND) and rolling direction (RD). Varying the initial orientation of the single crystal made it possible to reveal stable orientations, among which are textural components {001} <100>, {001} <110>, {111} <110> and {111} <112>. For orientation <111> of single crystal, in the matrix of a quasi-single crystal it was possible to detect a finely dispersed Ο‰-phase, which causes the appearance of an extended halo in the diffraction spectrum. The presence o

    Quest for Methods to Increase Aerobic Capacity in Cyclic Sports

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    Quest for new techniques to increase the aerobic training of the athletes, attempts to apply the methodology of training for semi-skilled athletes based on increasing of VO2 max (Maximal Oxygen Consumption) in slow twitch muscle fibersΠ’ ΡΡ‚Π°Ρ‚ΡŒΠ΅ рассмотрСны поиски Π½ΠΎΠ²Ρ‹Ρ… ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΈΠΊ ΠΏΠΎΠ²Ρ‹ΡˆΠ΅Π½ΠΈΡ аэробной ΠΏΠΎΠ΄Π³ΠΎΡ‚ΠΎΠ²ΠΊΠΈ Π»Π΅Π³ΠΊΠΎΠ°Ρ‚Π»Π΅Ρ‚ΠΎΠ², ΠΏΠΎΠΏΡ‹Ρ‚ΠΊΠ° ΠΏΡ€ΠΈΠΌΠ΅Π½ΠΈΡ‚ΡŒ ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΈΠΊΡƒ Ρ‚Ρ€Π΅Π½ΠΈΡ€ΠΎΠ²ΠΊΠΈ Π½Π° спортсмСнах срСднСй ΠΊΠ²Π°Π»ΠΈΡ„ΠΈΠΊΠ°Ρ†ΠΈΠΈ, ΠΎΡΠ½ΠΎΠ²Π°Π½Π½ΡƒΡŽ Π½Π° ΠΏΠΎΠ²Ρ‹ΡˆΠ΅Π½ΠΈΠΈ МПК Π² ΠΎΡ‚Π΄Π΅Π»ΡŒΠ½ΠΎ взятых ΠΌΠ΅Π΄Π»Π΅Π½Π½Ρ‹Ρ… ΠΌΡ‹ΡˆΠ΅Ρ‡Π½Ρ‹Ρ… Π²ΠΎΠ»ΠΎΠΊΠ½Π°

    Роль Π½Π΅ΠΉΡ‚Ρ€ΠΎΡ„ΠΈΠ»ΠΎΠ² Π² ΠΏΠ°Ρ‚ΠΎΠ³Π΅Π½Π΅Π·Π΅ ΠΈΡˆΠ΅ΠΌΠΈΡ‡Π΅ΡΠΊΠΎΠ³ΠΎ ΠΈΠ½ΡΡƒΠ»ΡŒΡ‚Π°

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    Background. Immune responses and inflammation play an important role in the pathogenesis of ischemic stroke.Aim. To analyze the involvement of neutrophils in the pathogenesis of ischemic stroke.Results. Data on the contribution of neutrophil granulocytes to the development of local sterile inflammation and secondary brain injury in acute ischemic stroke were summarized. Mechanisms of neutrophil influence on thrombosis, neutrophil extracellular trap formation (NETosis), protease release, and direct interaction with platelets with subsequent formation of platelet-leukocyte aggregates were discussed. Available information on the effectiveness of reperfusion therapy and an association of changes in neutrophil activity with development of infectious complications of stroke were presented. In addition, research data were presented on the contribution of neutrophils to atherogenesis, which is one of the most important etiological factors in ischemic stroke. The review showed that the contribution of neutrophils to the pathogenesis of ischemic stroke is associated with implementation of their secretory, regulatory, and phagocytic functions, as well as with NETosis.Conclusion. It was shown that neutrophils are involved in the pathogenesis of ischemic stroke and modulate a response to treatment.ΠΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ. Π˜ΠΌΠΌΡƒΠ½Π½Ρ‹Π΅ Ρ€Π΅Π°ΠΊΡ†ΠΈΠΈ ΠΈ Π²ΠΎΡΠΏΠ°Π»ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹ΠΉ процСсс ΠΈΠ³Ρ€Π°ΡŽΡ‚ Π²Π°ΠΆΠ½ΡƒΡŽ Ρ€ΠΎΠ»ΡŒ Π² ΠΏΠ°Ρ‚ΠΎΠ³Π΅Π½Π΅Π·Π΅ ΠΈΡˆΠ΅ΠΌΠΈΡ‡Π΅ΡΠΊΠΎΠ³ΠΎ ΠΈΠ½ΡΡƒΠ»ΡŒΡ‚Π°.ЦСль. На основании Π½Π°ΡƒΡ‡Π½Ρ‹Ρ… ΠΏΡƒΠ±Π»ΠΈΠΊΠ°Ρ†ΠΈΠΉ ΠΏΡ€ΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡ€ΠΎΠ²Π°Ρ‚ΡŒ Π²ΠΎΠ²Π»Π΅Ρ‡Π΅Π½Π½ΠΎΡΡ‚ΡŒ Π½Π΅ΠΉΡ‚Ρ€ΠΎΡ„ΠΈΠ»ΠΎΠ² Π² ΠΏΠ°Ρ‚ΠΎΠ³Π΅Π½Π΅Π· ΠΈΡˆΠ΅ΠΌΠΈΡ‡Π΅ΡΠΊΠΎΠ³ΠΎ ΠΈΠ½ΡΡƒΠ»ΡŒΡ‚Π°.Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹. ΠžΠ±ΠΎΠ±Ρ‰Π΅Π½Ρ‹ Π΄Π°Π½Π½Ρ‹Π΅ ΠΎ Π²ΠΊΠ»Π°Π΄Π΅ Π½Π΅ΠΉΡ‚Ρ€ΠΎΡ„ΠΈΠ»ΡŒΠ½Ρ‹Ρ… Π³Ρ€Π°Π½ΡƒΠ»ΠΎΡ†ΠΈΡ‚ΠΎΠ² Π² Ρ€Π°Π·Π²ΠΈΡ‚ΠΈΠ΅ локального асСптичСского воспалСния ΠΈ Π²Ρ‚ΠΎΡ€ΠΈΡ‡Π½ΠΎΠ³ΠΎ поврСТдСния ΠΌΠΎΠ·Π³Π° ΠΏΡ€ΠΈ остром ΠΈΠ½ΡΡƒΠ»ΡŒΡ‚Π΅. ΠžΠ±ΡΡƒΠΆΠ΄Π΅Π½Ρ‹ ΠΌΠ΅Ρ…Π°Π½ΠΈΠ·ΠΌΡ‹ влияния Π½Π΅ΠΉΡ‚Ρ€ΠΎΡ„ΠΈΠ»ΠΎΠ² Π½Π° процСсс тромбообразования, ΠΎΠ±Ρ€Π°Π·ΠΎΠ²Π°Π½ΠΈΠ΅ Π½Π΅ΠΉΡ‚Ρ€ΠΎΡ„ΠΈΠ»ΡŒΠ½Ρ‹Ρ… Π²Π½Π΅ΠΊΠ»Π΅Ρ‚ΠΎΡ‡Π½Ρ‹Ρ… Π»ΠΎΠ²ΡƒΡˆΠ΅ΠΊ (Π½Π΅Ρ‚ΠΎΠ·), высвобоТдСниС ΠΏΡ€ΠΎΡ‚Π΅Π°Π· ΠΈ прямоС взаимодСйствиС с Ρ‚Ρ€ΠΎΠΌΠ±ΠΎΡ†ΠΈΡ‚Π°ΠΌΠΈ с ΠΎΠ±Ρ€Π°Π·ΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ Π»Π΅ΠΉΠΊΠΎΡ†ΠΈΡ‚Π°Ρ€Π½ΠΎ-Ρ‚Ρ€ΠΎΠΌΠ±ΠΎΡ†ΠΈΡ‚Π°Ρ€Π½Ρ‹Ρ… Π°Π³Ρ€Π΅Π³Π°Ρ‚ΠΎΠ². ΠŸΡ€ΠΈΠ²Π΅Π΄Π΅Π½Ρ‹ ΠΈΠΌΠ΅ΡŽΡ‰ΠΈΠ΅ΡΡ свСдСния ΠΎΠ± эффСктивности Ρ€Π΅ΠΏΠ΅Ρ€Ρ„ΡƒΠ·ΠΈΠΎΠ½Π½ΠΎΠΉ Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ, Π° Ρ‚Π°ΠΊΠΆΠ΅ ассоциации ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ активности Π½Π΅ΠΉΡ‚Ρ€ΠΎΡ„ΠΈΠ»ΠΎΠ² с Ρ€Π°Π·Π²ΠΈΡ‚ΠΈΠ΅ΠΌ ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠΎΠ½Π½Ρ‹Ρ… ослоТнСний ΠΈΠ½ΡΡƒΠ»ΡŒΡ‚Π°. ΠŸΡ€Π΅Π΄ΡΡ‚Π°Π²Π»Π΅Π½Ρ‹ Π΄Π°Π½Π½Ρ‹Π΅ исслСдований ΠΎ Π²ΠΊΠ»Π°Π΄Π΅ Π½Π΅ΠΉΡ‚Ρ€ΠΎΡ„ΠΈΠ»ΠΎΠ² Π² Π°Ρ‚Π΅Ρ€ΠΎΠ³Π΅Π½Π΅Π·, ΡΠ²Π»ΡΡŽΡ‰ΠΈΠΉΡΡ ΠΎΠ΄Π½ΠΈΠΌ ΠΈΠ· Π²Π°ΠΆΠ½Π΅ΠΉΡˆΠΈΡ… этиологичСских Ρ„Π°ΠΊΡ‚ΠΎΡ€ΠΎΠ² ΠΈΡˆΠ΅ΠΌΠΈΡ‡Π΅ΡΠΊΠΎΠ³ΠΎ ΠΈΠ½ΡΡƒΠ»ΡŒΡ‚Π°. Показано, Ρ‡Ρ‚ΠΎ участиС Π½Π΅ΠΉΡ‚Ρ€ΠΎΡ„ΠΈΠ»ΠΎΠ² Π² ΠΏΠ°Ρ‚ΠΎΠ³Π΅Π½Π΅Π·Π΅ ΠΈΡˆΠ΅ΠΌΠΈΡ‡Π΅ΡΠΊΠΎΠ³ΠΎ ΠΈΠ½ΡΡƒΠ»ΡŒΡ‚Π° связано с Ρ€Π΅Π°Π»ΠΈΠ·Π°Ρ†ΠΈΠ΅ΠΉ ΠΈΡ… сСкрСторных, рСгуляторных, Ρ„Π°Π³ΠΎΡ†ΠΈΡ‚Π°Ρ€Π½Ρ‹Ρ… Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΉ ΠΈ с Π½Π΅Ρ‚ΠΎΠ·ΠΎΠΌ.Π—Π°ΠΊΠ»ΡŽΡ‡Π΅Π½ΠΈΠ΅. УстановлСно, Ρ‡Ρ‚ΠΎ Π½Π΅ΠΉΡ‚Ρ€ΠΎΡ„ΠΈΠ»Ρ‹ ΠΏΡ€ΠΈΠ½ΠΈΠΌΠ°ΡŽΡ‚ Π°ΠΊΡ‚ΠΈΠ²Π½ΠΎΠ΅ участиС Π² ΠΏΠ°Ρ‚ΠΎΠ³Π΅Π½Π΅Π·Π΅ ΠΈΡˆΠ΅ΠΌΠΈΡ‡Π΅ΡΠΊΠΎΠ³ΠΎ ΠΈΠ½ΡΡƒΠ»ΡŒΡ‚Π° ΠΈ ΠΌΠΎΠ΄ΡƒΠ»ΠΈΡ€ΡƒΡŽΡ‚ ΠΎΡ‚Π²Π΅Ρ‚ Π½Π° Π»Π΅Ρ‡Π΅Π½ΠΈΠ΅

    Experience of radiotechnical college interaction with enterprises within the framework of realization of the fed-eral target program of development of professional education

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    Π’ ΡΡ‚Π°Ρ‚ΡŒΠ΅ прСдставлСны Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ совмСстной Π΄Π΅ΡΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΠΈ Π² Ρ€Π°ΠΌΠΊΠ°Ρ… Ρ€Π΅Π°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ Π€Π΅Π΄Π΅Ρ€Π°Π»ΡŒΠ½ΠΎΠΉ Ρ†Π΅Π»Π΅Π²ΠΎΠΉ ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌΡ‹ развития ΠΏΡ€ΠΎΡ„Π΅ΡΡΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ образования КамСнск-Π£Ρ€Π°Π»ΡŒΡΠΊΠΎΠ³ΠΎ радиотСхничСского Ρ‚Π΅Ρ…Π½ΠΈΠΊΡƒΠΌΠ° с прСдприятиями ΠΎΠ±ΠΎΡ€ΠΎΠ½Π½ΠΎ-ΠΏΡ€ΠΎΠΌΡ‹ΡˆΠ»Π΅Π½Π½ΠΎΠ³ΠΎ комплСкса участвовал Π² Ρ€Π΅Π°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ.This article shows the results of Kamensk-Uralsky Radio technical College collaboration with the defenceindustrial sector enterprises in the framework of the implementation of the Federal tar-get program of professional education development

    Biotransformation patterns of 2,4,6-trinitrotoluene by aerobic bacteria

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    2,4,6-Trinitrotoluene (TNT), a toxic nitroaromatic explosive, accumulates in the environment, making necessary the remediation of contaminated areas and unused materials. Although bioremediation has been utilized to detoxify TNT, the metabolic process involved in the metabolism of TNT have proven to be complex. The three aerobic bacterial strains reported here (Pseudomonas aeruginosa, Bacillus sp., and Staphylococcus sp.) differ in their ability to biotransform TNT and in their growth characteristics in the presence of TNT. In addition, enzymatic activities have been identified that differ in the reduction of nitro groups, cofactor preferences, and the ability to eliminate-NO2 from the ring. The Bacillus sp. has the most diverse bioremediation potential owing to its growth in the presence of TNT, high level of reductive ability, and capability of removing-NO2 from the nitroaromatic ring

    Amino-nitrile cleavage in the electrochemical reduction of hydeazones of aromatic aldehydes

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    1. Factors which determine the possibility of amino-nitrile cleavage of hydrazones on electrochemical reduction (ECR) include the basicity of the anionic product formed in the course of the ECR and the mobility of the aldehyde hydrogen which depends on the character of the electron polarization of the hydrazone fragment and the polarity of the N-N bond. 2. The primary action in amino-nitrile cleavage under conditions of ECR is the deprotonation of the azomethine fragment in the unreduced molecule by electrochemically generated strong base (anion or dianion). Β© 1988 Plenum Publishing Corporation

    Interdisciplinary Studies of the Mausoleum Complex Nearby the Village of Lapas (2022–2023)

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    Nearby the village of Lapas in the Astrakhan region, there is a complex of Golden Horde mausoleums. In 2022, 2023 the Institute of Archaeology named after A.Kh. Khalikov of the Tatarstan Academy of Sciences continued the comprehensive studies of this site. The results of the excavations allowed: to identify part of the mausoleum structures (brick floor, coated with alabaster mortar); to confirm information about the dismantling of the building walls for bricks; correct the interpretation of magnetometry data. In 2022, the mausoleum complex was photographed using an aerial laser scanning. A digital elevation model (DEM) was created, the analysis of which allowed us to assume the presence of previously unknown mausoleums. In 2023, using magnetometry, the remains of several complexes, probably structures made of raw bricks on the same site, were recorded, which can be divided into groups according to orientation. The results obtained confirm the presence of an unknown number of objects of this monument that have not yet been identified, and outline ways for further studies

    The role of the Sverdlovsk state medical institute in testing drugs, developed by the ural scientists

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    The article presents the contribution of scientists of Sverdlovsk state medical institute to the testing of new drugs developed in the Urals during pre-war years and the years of the great Patriotic war.Π’ ΡΡ‚Π°Ρ‚ΡŒΠ΅ прСдставлСн Π²ΠΊΠ»Π°Π΄ ΡƒΡ‡Π΅Π½Ρ‹Ρ… БвСрдловского государствСнного мСдицинского института Π² Π°ΠΏΡ€ΠΎΠ±Π°Ρ†ΠΈΡŽ Π½ΠΎΠ²Ρ‹Ρ… лСкарствСнных ΠΏΡ€Π΅ΠΏΠ°Ρ€Π°Ρ‚ΠΎΠ², Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚Π°Π½Π½Ρ‹Ρ… Π½Π° Π£Ρ€Π°Π»Π΅ Π² Π΄ΠΎΠ²ΠΎΠ΅Π½Π½Ρ‹Π΅ Π³ΠΎΠ΄Ρ‹ ΠΈ Π³ΠΎΠ΄Ρ‹ Π’Π΅Π»ΠΈΠΊΠΎΠΉ ΠžΡ‚Π΅Ρ‡Π΅ΡΡ‚Π²Π΅Π½Π½ΠΎΠΉ Π²ΠΎΠΉΠ½Ρ‹

    Reflection of the issues of the organization of medical care in the local periodical press in 1980-1990

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    The article considers the content of publications in the local press of the city of Rezh in the Sverdlovsk region in the 1980s on medical topics. It was found that the heads of the health care of the city of Rezh reported in detail to the population about the achievements and problems in the organization of medical care. Newspaper publications were also used as a tool to morally stimulate medical workers and increase the sanitary and hygiene literacy of the population.Π’ ΡΡ‚Π°Ρ‚ΡŒΠ΅ рассмотрСно содСрТаниС ΠΏΡƒΠ±Π»ΠΈΠΊΠ°Ρ†ΠΈΠΉ Π² мСстной ΠΏΠ΅Ρ‡Π°Ρ‚ΠΈ Π³. Π Π΅ΠΆ БвСрдловской области Π·Π° 1980-Π΅ Π³ΠΎΠ΄Ρ‹ Π½Π° ΠΌΠ΅Π΄ΠΈΡ†ΠΈΠ½ΡΠΊΡƒΡŽ Ρ‚Π΅ΠΌΠ°Ρ‚ΠΈΠΊΡƒ. УстановлСно, Ρ‡Ρ‚ΠΎ Ρ€ΡƒΠΊΠΎΠ²ΠΎΠ΄ΠΈΡ‚Π΅Π»ΠΈ рСТСвского здравоохранСния ΠΏΠΎΠ΄Ρ€ΠΎΠ±Π½ΠΎ ΠΎΡ‚Ρ‡ΠΈΡ‚Ρ‹Π²Π°Π»ΠΈΡΡŒ ΠΏΠ΅Ρ€Π΅Π΄ насСлСниСм ΠΎ достиТСниях ΠΈ ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΠ°Ρ… ΠΏΡ€ΠΈ ΠΎΡ€Π³Π°Π½ΠΈΠ·Π°Ρ†ΠΈΠΈ мСдицинской ΠΏΠΎΠΌΠΎΡ‰ΠΈ. Π“Π°Π·Π΅Ρ‚Π½Ρ‹Π΅ ΠΏΡƒΠ±Π»ΠΈΠΊΠ°Ρ†ΠΈΠΈ Ρ‚Π°ΠΊΠΆΠ΅ использовались Π² качСствС инструмСнта ΠΌΠΎΡ€Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ стимулирования мСдицинских Ρ€Π°Π±ΠΎΡ‚Π½ΠΈΠΊΠΎΠ² ΠΈ ΠΏΠΎΠ²Ρ‹ΡˆΠ΅Π½ΠΈΡ санитарно-гигиСничСской грамотности насСлСния
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