Pancreas transplantation for diabetic patients in Hawaii.

Diabetes mellitus is a common disease affecting a large population in Hawaii. Over the past 20 years, pancreas transplantation has evolved into a viable therapeutic option for selected patients with diabetes mellitus. This report describes the first combined pancreas-kidney transplant performed in Hawaii on June 28, 1993 on a patient with juvenile-onset diabetes mellitus and diabetic nephropathy. The patient has remained off insulin and off dialysis since the transplant. The history, indications, techniques, and potential complications related to this procedure are discussed

Impact of deoxygenation and warming on global marine species in the 21st century

Ocean temperature and dissolved oxygen shape marine habitats in interplay with species&rsquo; physiological characteristics. Therefore, the observed and projected warming and deoxygenation in the 21st century of the world&rsquo;s oceans may strongly affect species&rsquo; habitats. Here, we implement an extended version of the Aerobic Growth Index (AGI), which quantifies whether a viable population of a species can be sustained in a particular location. We assess the impact of projected deoxygenation and warming on the contemporary habitat of 47 representative marine species covering the epipelagic, mesopelagic/bathypelagic, and demersal realms. AGI is calculated for these species for the historical period and into the 21st century using bias-corrected environmental data from six comprehensive Earth System Models. While habitat viability decreases nearly everywhere with global warming, impact of this decrease is strongly species-dependent. Most species lose less than 5 % of their contemporary habitat volume over the 21st century even at 3 &deg;C of global warming relative to preindustrial, although some individual species are projected to incur losses 2&ndash;3 times greater than that. We find that the contemporary spatiotemporal variability of O2 and temperature (and hence AGI) provides a quantifiable measure of a species&rsquo; vulnerability to change. Species&rsquo; vulnerability is the most important indicator for large (&gt;5 %) potential habitat losses &ndash; not relative or absolute changes in habitat viability (i.e., AGIrel or &Delta;AGI), temperature or O2. Loss of contemporary habitat is for most epipelagic species driven by warming of ocean water and is therefore expanded with increased levels of global warming. In the mesopelagic/bathypelagic and demersal realms habitat loss is also affected by pO2 decrease for some species. Our analysis is constrained by the uncertainties involved in species-specific critical thresholds, which we quantify, by data limitations on 3D species distributions as well as by high uncertainty in model O2 projections in equatorial regions. Focus on these topics in future research will strengthen our confidence in assessing climate-change driven losses of contemporary habitat across the global oceans.</p

The stabilizing role of itinerant ferromagnetism in inter-granular cohesion in iron

We present a simple, general energy functional for ferromagnetic materials based upon a local spin density extension to the Stoner theory of itinerant ferromagnetism. The functional reproduces well available ab initio results and experimental interfacial energies for grain boundaries in iron. The model shows that inter-granular cohesion along symmetric tilt boundaries in iron is dependent upon strong magnetic structure at the interface, illuminates the mechanisms underlying this structure, and provides a simple explanation for relaxation of the atomic structure at these boundaries.Comment: In review at Phys. Rev. Lett. Submitted 23 September 1997; revised 16 March 199

Emotional Labor and Occupational Well-Being: Latent Profile Transition Analysis Approach

This study used the latent profile transition analysis (LPTA) to analyze whether emotional labor profiles change across time and how these profiles relate to occupational well-being (i.e., job satisfaction, quality of work life, psychological distress, and work–family conflict). A total of 155 full-time Chinese employees completed the questionnaire survey at two time points. Three latent profiles were identified at Time 1 and the same profiles were replicated at Time 2. We determined that the majority of the participants retained the original profiles. Lastly, occupational well-being differed significantly across the identified profiles. The limitations and implications of this study were also provided

Study of Radiative Leptonic D Meson Decays

We study the radiative leptonic $D$ meson decays of D^+_{(s)}\to \l^+\nu_{\l}\gamma (\l=e,\mu,\tau), $D^0\to \nu\bar{\nu}\gamma$ and D^0\to \l^+\l^-\gamma ($l=e,\mu$) within the light front quark model. In the standard model, we find that the decay branching ratios of $D^+_{(s)}\to e^+\nu_e\gamma$, $D^+_{(s)}\to\mu^+\nu_{\mu}\gamma$ and $D^+_{(s)}\to\tau^+\nu_{\tau}\gamma$ are $6.9\times 10^{-6}$ ($7.7\times 10^{-5}$), $2.5\times 10^{-5}$ ($2.6\times 10^{-4}$), and $6.0\times 10^{-6}$ ($3.2\times 10^{-4}$), and that of D^0\to\l^+\l^-\gamma (\l=e,\mu) and $D^0\to\nu\bar{\nu}\gamma$ are $6.3\times 10^{-11}$ and $2.7\times 10^{-16}$, respectively.Comment: 23 pages, 6 Figures, LaTex file, a reference added, to be published in Mod. Phys. Lett.

Chandra and HST observations of gamma-ray blazars: comparing jet emission at small and large scales

We present new Chandra and HST data for four gamma-ray blazars selected on the basis of radio morphology with the aim of revealing X-ray and optical emission from their jets at large scales. All the sources have been detected. Spectral Energy Distributions of the large scale jets are obtained as well as new X-ray spectra for the blazar cores. Modeling for each object the core (sub-pc scale) and large-scale (>100 kpc) jet SEDs, we derive the properties of the same jet at the two scales. The comparison of speeds and powers at different scales supports a simple scenario for the dynamics and propagation of high power relativistic jets.Comment: Accepted for publication in Ap

Improving coastal livelihoods through sustainable aquaculture practices - a report to the collaborative APEC Grouper Research and Development Network

Wild-harvest fisheries for live reef fish are largely over-exploited or unsustainable because of over-fishing and the widespread use of destructive fishing practices such as blast and cyanide fishing. Sustainable aquaculture – such as that of groupers – is one option for meeting the strong demand for reef fish, as well as potentially maintaining or improving the livelihoods of coastal communities. This report from a short study by the STREAM Initiative draws on secondary literature, media sources and four diverse case studies from at-risk reef fisheries, to frame a strategy for encouraging sustainable aquaculture as an alternative to destructive fishing practices. It was undertaken as a component of the APEC-funded project Collaborative Grouper Research and Development Network (FWG/01/2001) to better understand how recent technical advances in grouper culture and other complementary work – including that of the Asia-Pacific Marine Finfish Aquaculture Network (APMFAN) hosted by NACA – could better support the livelihoods of poor coastal communities. (PDF contains 49 pages

Improving selection procedures in health professions education from the applicant perspective:an interview study

Introduction: Applicant perceptions of selection impact motivation and performance during selection, and student diversity. However, in-depth insight into which values underly these perceptions is lacking, creating challenges for aligning selection procedures with applicant perceptions. This qualitative interview study aimed to identify values applicants believe should underlie selection, and how, according to applicants, these values should be used to make specific improvements to selection procedures in undergraduate health professions education (HPE). Methods: Thirty-one applicants to five undergraduate HPE programs in the Netherlands participated in semi-structured interviews using Appreciative Inquiry, an approach that focuses on what goes well to create vision for improvement, to guide the interviews. Transcriptions were analyzed using thematic analysis, adopting a constructivist approach. Results: Applicants’ values related to the aims of selection, the content of selection, and the treatment of applicants. Applicants believed that selection procedures should aim to identify students who best fit the training and profession, and generate diverse student populations to fulfill societal needs. According to applicants, the content of selection should be relevant for the curriculum and profession, assess a comprehensive set of attributes, be of high quality, allow applicants to show who they are, and be adapted to applicants’ current developmental state. Regarding treatment, applicants believed that selection should be a two-way process that fosters reflection on study choice, be transparent about what applicants can expect, safeguard applicants’ well-being, treat all applicants equally, and employ an equitable approach by taking personal circumstances into account. Applicants mentioned specific improvements regarding each value. Discussion: Applicants’ values offer novel insights into what they consider important preconditions for the design of selection procedures. Their suggested improvements can support selection committees in better meeting applicants’ needs.</p