Optimization of Flagellar Locomotion in the low Reynolds Number Regime

This report investigates the computational and theoretical techniques - modeled by E. Lauga and C. Eloy - used to optimize the shape of an activated flagellum for enhanced cell motility. Cell motility is ubiquitous and has a large affect on biological systems such as marine life ecosystems, reproduction, and infection. The physical principles governing flagellar propulsion are explored using computational fluid dynamics simulations, mathematical modeling, and the sequential quadratic programming (SQP) optimization algorithm. Through iterative refinement, we can identify optimized flagellar shapes that would minimize the energetic cost dependent on a single dimensionless sperm numbers (Sp). The computation of the optimum shapes are discretized into a series of Fourier modes that are parameterized by Sp. This research provides valuable insights into the design principles underlying efficient flagellar locomotion, with potential applications in biophysics

Tackling Higher Derivative Ghosts with the Euclidean Path Integral

An alternative to the effective field theory approach to treat ghosts in higher derivative theories is to attempt to integrate them out via the Euclidean path integral formalism. It has been suggested that this method could provide a consistent framework within which we might tolerate the ghost degrees of freedom that plague, among other theories, the higher derivative gravity models that have been proposed to explain cosmic acceleration. We consider the extension of this idea to treating a class of terms with order six derivatives, and find that for a general term the Euclidean path integral approach works in the most trivial background, Minkowski. Moreover we see that even in de Sitter background, despite some difficulties, it is possible to define a probability distribution for tensorial perturbations of the metric.Comment: 21 page

Sphaleron-Bisphaleron bifurcations in a custodial-symmetric two-doublets model

The standard electroweak model is extended by means of a second Brout-Englert-Higgs-doublet. The symmetry breaking potential is chosen is such a way that (i) the Lagrangian possesses a custodial symmetry, (ii) a static, spherically symmetric ansatz of the bosonic fields consistently reduces the Euler-Lagrange equations to a set of differential equations. The potential involves, in particular, products of fields of the two doublets, with a coupling constant $\lambda_3$.Static, finite energy solutions of the classical equations are constructed. The regular, non-trivial solutions having the lowest classical energy can be of two types: sphaleron or bisphaleron, according to the coupling constants. A special emphasis is put to the bifurcation between these two types of solutions which is analyzed in function of the different constants of the model,namely of $\lambda_3$.Comment: 10 pages, 3 figure