Family’s World in Mirror of Women’s Press in New Economic Policy’s Period

The transformation of the women’s press during the NEP period is examined in the article, attention is paid to the specifics of the functioning of family and household magazines for women, on the pages of which both the reforms and events of the Soviet era and pre-revolutionary values were reflected. The authors strive to identify the role that the “Magazine for Housewives” and “Women’s Magazine” played during the NEP period, supporting the family world in all its diverse social and spiritual manifestations; to clarify the ratio of traditional and innovative journalistic approaches in the formation of family and everyday media discourse. The results of a quantitative and qualitative content analysis of the publications of the “Magazine for Housewives” and “Women’s Magazine” of the NEP period are presented in the article. The novelty of the research is seen in the analysis of the structural, thematic, functional features of women’s magazines of the NEP era. Special attention is paid to the author’s body, including the previously unexplored works of A. S. Voznesensky (real name — Brodsky), who signed his materials with the pseudonym “Ilya Rentz”. It is concluded that non-state women’s editions of family and household orientation appealed to the experience of pre-revolutionary journalism and, discussing the reform of everyday life and family, continued to write about traditional family values

Electrocardiographic signs of impaired depolarization (fragmented QRS, early ventricular repolarization, etc.) as markers of left ventricular systolic dysfunction

Aim. To study the relationship between a decrease in left ventricular (LV) ejection fraction (EF) and conventional electrocardiographic (ECG) signs associated with myocardial structure changes (pathological Q wave, ventricular arrhythmias), and relatively novel and less studied (fragmented QRS (fQRS), early ventricular repolarization (EVR)) and to evaluate their significance for identifying patients with mildly-reduced EF (mrEF).Material and methods. The study included 148 patients who were treated and examined at the Almazov National Medical Research Center. During the ECG analysis, fQRS, EVR, pathological Q wave, and ventricular arrhythmias (VAs) were assessed. Echocardiography data were analyzed. Statistical processing was carried out, including Fisher and chi-squared test, as well as correlation and ROC analysis.Results. Depending on the EF level, patients were divided into three groups: group 1 — patients with reduced EF (rEF) (<40%); group 2 — patients with mrEF (40-49%); group 3 — patients with preserved EF (pEF) (>50%). In the 1st group (with rEF), fQRS was registered in 16 (51,6%) patients, in the 2nd (with mrEF) — in 13 (44,8%), in the 3rd (with EF >50%) — in 16 (18,2%). Pathological Q wave was detected in the 1st group (rEF) in 20 (65%) patients, in the 2nd (mrEF) — in 10 (35%); in the 3rd (pEF) — in 15 (18%) (p<0,001). ROC analysis found that fQRS is more important for identifying patients with mrEF. In the 1st group (rEF), EVR was registered in 2 (6,5%) patients, in the 2nd (pEF) — in 2 (6,9%), in the 3rd (EF>50%) — in 11 (12,5%); the differences were not significant (p=0,5). The relationship of EVR, the number of PVCs and the presence of ventricular tachycardia with EF was not revealed.Conclusion. FQRS is significantly more often observed with a decrease in EF and may be a marker of an mildly-reduced EF. There were no significant correlations between EVR and EF. There was also no relationship between VAs and LV systolic dysfunction

Водный, тепловой и солевой баланс юго-восточной части Баренцева моря

The south-eastern part of the Barents Sea is located away from the main currents, with a combination of climatic, hydrological and oceanological processes creating conditions that make the region different from the rest of the Barents Sea such that it is seen as a separate region and called sometimes the Pechora Sea. Despite the intensive economic activity in the south-eastern part of the Barents Sea, it is not yet clear to what extent the general Atlantic water transport in the Barents Sea and, consequently, the transport of heat and salt, affects this region. Therefore, the aim of this study was to assess advective flows at open boundaries, as well as other components of the water, heat and salt balances of the south-eastern part of the Barents Sea. Based on monthly average data from the MERCATOR GLORYS12V1 reanalysis for the period 1993–2018, we calculated water transport, heat and salt flows at the boundaries of the south-eastern part of the Barents Sea (at 50° E in the west, at 71° N in the north and in the Kara Gate Strait); to close the balances, an assessment was made of sea-atmosphere interaction characteristics on the sea surface based on ECMWF ERA5 reanalysis data. Water, heat and salt balances were combined with a residual not exceeding 1.6 %. Linear trends for the characteristics obtained were calculated. It is revealed that the average long-term resulting water transport in the south-eastern part of the Barents Sea is directed from the north-west of the region to the Kara Gate Strait (0.40 Sv). This current is associated with the Atlantic waters and also carries heat and salt. The resulting heat input (5.92 TW) creates a heat excess in the water area, which is compensated for by interaction with the atmosphere (1.86 TW). The salt flow through the region is estimated at 13.98 t/s. During the study period, all the main flows have a statistically significant positive trend in the incoming and outgoing parts of the balances: water transport — 0.005 Sv per year; salt flow — 0.18 t/s per year. This indicates an increase in the transit of Atlantic waters through the south-eastern part of the Barents Sea. An increase in the advective heat flux (0.15 TW per year) across the western border is accompanied by an increase in its release into the atmosphere (0.07 TW per year) and an increase in evaporation of 6.9 mm per year. Sea levels are also rising at a rate of 0.27 cm per year. Thus, the increasing dynamics of the processes in the region is a factor to take into account in conducting economic activities.В статье представлены оценки адвективных потоков на открытых границах, а также других компонентов водного, теплового и солевого балансов юго-восточной части Баренцева моря (иногда называемой Печорским морем). По среднемесячным данным реанализов MERCATOR GLORYS12V1 и ECMWF ERA5 за период 1993–2018 гг. рассчитаны объемный расход воды, потоки тепла и соли на границах юго-восточной части Баренцева моря (западная граница по 50° в. д., северная граница по 71° с. ш. и разрез в проливе Карские Ворота); потоки тепла и влаги на поверхности моря. Балансы воды, тепла и соли собраны с невязкой, не превышающей 1,6 %. Выявлено, что адвекция через границы акватории играет главную роль в формировании всех балансов. Основной поток вод направлен с северо-запада акватории транзитом через пролив Карские Ворота в Карское море. На основании анализа линейных трендов показано, что все основные потоки имеют значимый положительный тренд. Это указывает на рост транзита атлантических вод через юго-восточную часть Баренцева моря. Также отмечен рост испарения и теплоотдачи с поверхности моря, связанный с ростом температуры воды

Anthocyanins as functional food components

Among the natural pigments, anthocyanins are assumed to represent one of the most studied groups. Starting with the first studies on the physicochemical properties of anthocyanins carried out in the 17th century by British naturalist Robert Boyle, the science about these unique compounds has progressed substantially. To date, the structure and functions of anthocyanins in plant cells have been well studied, and the pathway of their biosynthesis is one of the most fully characterized pathways of secondary metabolite biosynthesis at both the biochemical and genetic levels. Along with these fundamental achievements, we are beginning to realize the potential of anthocyanins as compounds of industrial importance, as pigments themselves, as well as components of functional food that contribute to the prevention and reduction of risk of chronic diseases. For a long time, the biological activity of anthocyanins has been underestimated, in particular, due to the data on their low bioavailability. However, studies showed that in humans and animals, these compounds are actively metabolized and the bioavailability, estimated taking into account their metabolites, exceeded 12 %. It has been experimentally shown that anthocyanins have antioxidant, anti-inflammatory, hypoglycemic, antimutagenic, antidiabetic, anti-cancer, neuroprotective properties, and they are beneficial for eye health. However, the studies conducted cannot always explain the molecular mechanism of action of anthocyanins in the human body. According to some reports, the observed effects are not due to the action of anthocyanins themselves, but to their metabolites, which can be more biologically active because of their increased bioavailability. Other data ascribe the positive effect on human health not to individual anthocyanins, but to the whole complex of polyphenolic compounds consumed. The review summarizes the results of the studies of anthocyanins as components of functional food. Special attention is paid to genetic control of the pigment synthesis. These data are of particular importance in respect to the initiated breeding programs aimed at increasing the content of anthocyanins in cultural plants

Gender differences in the structure of the cerebrospinal fluid system of pre-school children

Relevance Investigation of the cerebrospinal fluid system of children of different ages, especially pre-school and school periods of childhood, becomes essential, since the further development of the brain and its proper functioning depends on the way it functions. Considering the MRI indications of the elements of the cerebrospinal fluid system of children is important for the development of neurology and neurosurgery, it is necessary to consider gender differences in the brain size and structure.Objective To study the sex differences in the structure of the cerebrospinal fluid system in seven-year-old children.Material and Methods For the study, archival data on the sizes of the lateral ventricles of the brain of 120 children aged 7 (60 boys and 60 girls) were involved, in particular: 1) the length of the anterior horn; 2) the width of the anterior horn; 3) the length of the central part; 4) the width of the central part; 5) the length of the posterior horn; 6) the width of the posterior horn; 7) the length of the lower horn; 8) the anteroposterior size; 9) the distance between the anterior horns; 10) the distance between the posterior horns; 11) the length of the third ventricle; 12) the height of the third ventricle; 13) the length of the aqueduct; 14) the length of the fourth ventricle; 15) the height of the fourth ventricle. The studies were carried out using the method of magnetic resonance imaging. Quantitative indicators were assessed for compliance with the normal distribution using the KolmogorovSmirnov test. The accumulation, correction, systematization of the initial information were carried out in Microsoft Excel 2016. Statistical analysis was carried out using the Statistica 10.0 software (StatSoft Inc., USA). The results were considered statistically significant at p < 0.05.Results The data obtained in the study of the cerebrospinal fluid system in children during their pre-school period of childhood are indicators of the norm and can be used for diagnostic studies in the departments of radiation diagnostics. The bilateral asymmetry of the lateral ventricles of the brain in pre-school children, discovered during the work, is of crucial clinical significance. The morphometric indicators of the elements of the cerebrospinal fluid system should be considered by specialists in the study of brain neuroplasticity.Conclusion Analysis of the obtained in vivo encephalometric data indicates the presence of sexual variability of the brain and parameters of the structures of the cerebrospinal fluid

Improvement of the Normative-Regulatory Framework Concerning Anti-Epidemic Procedures for Works with Infectious Disease Agents in Mobile Laboratories of Specialized Anti-Epidemic Teams (SAET)

Carried out is a range of investigations aimed at the improvement of the anti-epidemic procedures for works with infectious disease agents (herein biological safety provision) in mobile laboratories of specialized anti-epidemic teams (SAET). Evaluation of the operational experience of stationary and field laboratories, as well as comparative analysis of the national safety requirements for works with pathogenic biological agents and WHO international regulations in the sphere of biological safety provision in laboratories, has made it possible to outline common for all types of microbiological laboratories principles for biosafety provision. With due consideration of these principles formulated are the core requirements for the provision of biological safety of SAET activities. Based on the results of biorisk and biohazard assessment which have to do with innovative mobile laboratories, worked out is a system of anti-epidemic procedures aimed towards establishment of the conditions that offer as low as practically achievable level of risk for personnel of SAET mobile laboratories, for population and human environment too. These practices, designed for biological safety provision among the personnel of mobile laboratories (ML), have been played back in a number of standard operational procedures. With a view to establishing of the environment with acceptable level of biorisk for the personnel and population when ML are used for various purposes and in various contingencies (in full force, single unit or several modules), worked out are the algorithms of decision-making support as regards selection of modules and optional accessories. However, there is a need for emergency response plans and training programs for the personnel on the provision of biosafety in ML to ensure and maintain acceptable level of biorisk connected with ML functioning

Оптимизм и страх заражения как предикторы следования рекомендациям оставаться дома во время пандемии Covid-19

According to COVID-19 research, the introduction of a self-isolation and quarantine regime is an effective measure to contain the pandemic. The article examines the problem of psychological factors of observing stay-at-home recommendations, among which the main attention is paid to two types of optimism in a pandemic situation: constructive optimism and defensive optimism. It was assumed that they would have the opposite effect on adherence to the self-isolation regime, and the negative effect of defensive optimism would be mediated by a decrease in illness anxiety or fear of infection. To test this hypothesis, a longitudinal study (with an interval of six weeks) was carried out in a sample of 306 students (89% of women) using a life orientation test, the scales of constructive and defensive optimism by Gordeeva et al., and anxiety in a pandemic situation questionnaire by Tkhostov and Rasskazova. The results confirm our hypotheses: people who adhere to the stay-at-home recommendations are characterized by a higher level of constructive optimism, i.e. they believe that their efforts will help prevent infection and spread of the virus. In contrast, people who demonstrate unrealistic or defensive optimism, that is, who believe that the issue of coronavirus is exaggerated, fear infection less and admit that they do not strictly adhere to the requirements of self-isolation. These results indicate that, in addition to dispositional optimism, situation specific constructive and defensive optimism are essential in explaining health behavior, with the latter type of optimism serving as a response to anxiety associated with fear of the disease and its consequences. © 2021 Moscow State University of Psychology and Education. All Rights Reserved.Funding. The reported study was funded by Russian Foundation for Basic Research (RFBR), project number 20-04-60174

Study of the Influence of Extraction Parameters on the Process of Extraction of Lanthanum and Actinium from a Collective Ree Solution

Extraction of lanthanum and actinium from a model REE solution was carried out by extraction methods using a neutral tributyl phosphate extractant. The influence of extraction conditions on the process of extraction of lanthanum and actinium from a REE nitric acid solution has been studied

Features of the brainstem and its cavities in three-year-old children

Background: Little is known about the brainstem in healthy three-year-old children; yet there is a need for further studies because children at this age are growing and developing rapidly.Objective: To study differences in the brainstem and its cavities in healthy three-year-old children, considering the sex and bilateral asymmetry.Materials and methods: We retrospectively analyzed 120 MRI scans of healthy three-year-old children (60 boys and 60 girls) to study the brainstem features. The following parameters of the brain stem structures were assessed: 1) the length of the pons (mm), 2) the height of the pons (mm), 3) the length of the medulla oblongata (mm), 4) the height of the medulla oblongata at the upper and lower borders (mm), 5) the length and height of the vermis (mm), 6) the width of the cerebellum (mm), 7) the length, width, height of the cerebellar hemispheres (mm), 8) the length and height of the third ventricle, 9) the length of the cerebral aqueduct (mm), 10) the length and height of the fourth ventricle (mm). We assessed the compliance of quantitative parameters with the normal distribution according to the Kolmogorov-Smirnov criterion. We used Microsoft Excel 2016 tables to accumulate, correct and systemize the raw data. Statistica 10.0 software (StatSoft. Inc., USA) along with the corresponding statistical method provided the digital data. The differences were considered significant at P < .05.Results: We aimed to study sex-related differences in the basic sizes of the brainstem. The length and height of the pons, the length of the third and the fourth ventricles, and the size of the cerebellar hemispheres were greater in boys. We found a bilateral asymmetry in cerebellar hemispheres (length, width, and height).Conclusions: The changes in the complex brainstem of three-year-old children are sex-dependent and consist in active transformations of its structures

Study of relationships between HLA-G gene polymorphism, intrauterine infection and recurrent miscarriage in women

The relationship between the HLA-G gene polymorphism (rs41551813, rs12722477, rs41557518), intrauterine infection and recurrent miscarriage (RM) in women were studied. The case group consisted of 180 patients with RM, defined as two or more consecutive miscarriages (min = 2; max = 8) at up to 20 weeks of gestation, and with clinically confirmed pregnancies and non-viable fetuses. At the time of examination. the women were enrolled from the Genetic Counseling Center at the Kemerovo Regional Clinical Hospital, Kemerovo, Russia, and were not pregnant. Each patient underwent a gynecological examination. We excluded women with a history of medical abortion, birth, and ectopic pregnancies. In addition, we excluded women with endocrine (e.g. diabetes) disorders. To exclude other known causes of spontaneous abortion, the following tests were performed: ultrasound examination of pelvic organs, and karyotyping in women and men. The women’s mean age in the RM group, was 29.6±4.8 (SD) years. The control group comprised 408 fertile women. These women didn’t have a history of spontaneous abortion, or a family history of congenital malformations. They have born, at least, 1-2 healthy children. Women’s mean age at birth of last child was 26.8±5.2 (SD) years. Influence of the intrauterine infection was analyzed on the basis of laboratory tests. Diagnostics of bacterial vaginosis and vulvo-vaginal candidiasis by microscopic examination was conducted. Viral agent infections (herpes simplex virus type 2, cytomegalovirus, human papilloma virus type 16/18), Chlamydia trachomatis, Mycoplasma hominis, Ureaplasma urealyticum, Gardnerella vaginalis and Trichomonas vaginalis were detected by enzyme-linked immunoassay and polymerase chain reaction (PCR). The data were obtained from the medical cards of the surveyed women. All the women gave a written informed consent before participating in the study. Typing of polymorphisms of Thr31Ser (rs41551813, HLA-G*01:03) in exon 2, Leu110Ile (rs12722477, HLA-G*01:04) and 1597 delС (rs41557518, HLA-G*01:05N) in exon 3 HLA-G genes were performed by realtime PCR followed by melting analysis. The study showed that the intrauterine infection was not a risk factor for RM (p = 0.30) in the examined women. It was found that the 110 Ile allele (HLA-G *01:04) was a risk factor for RM both in women with intrauterine infection [ORa = 4.50 (2.41-8.38), p = 2.09e-06], and in women without infection [ORa = 2.46 (1.44-4.21), p = 0.0009]. The cooperative influence of genetic and infections factors with the risk of RM in women was revealed [ORa+f = 3.50 (2.01-6.09), p = 8.78e-06]. Our results will be useful in understanding the molecular mechanisms of immune disorders in fetomaternal interface, and for choosing the strategy of management and treatment in women with RM