Simulation of ions interaction with biological environment using Geant4

Computer model that makes it possible to study the interaction of ion beam with biological objects has been created. Contribution of secondary particles to the formation of the total radiation dose was investigated. The model contains all the necessary elements of formation of ion beam and we can interactively change the parameters of the model. For processing of simulation results additional program codes were created. Studies were carried out on the object which size and physicochemical properties are similar to biological cell in the human body

New approach to the approximation of «dose – effect» dependence during the human somatic cells irradiation

New data on cytogenetic approximation of the experimental cytogenetic dependence "dose - effect" based on the spline regression model that improves biological dosimetry of human radiological exposure were received. This is achieved by reducing the error of the determination of absorbed dose as compared to the traditional use of linear and linear-quadratic models and makes it possible to predict the effect of dose curves on plateau