366 research outputs found
Australian Transnational Educational Leadership Roles: Challenges, Opportunities and Experiences
The establishment of higher educational hubs in Malaysia and Singapore has spurred the growth of transnational education (TNE) offerings in Asia, and attracted several Australian higher education providers to set up branch campuses in these countries. In Malaysia, TNE is seen as contributing to economic targets by helping to decrease the outflow of students and currency, and by attracting international students to Malaysian shores (British Council 2012). The provision of higher education through TNE raises issues somewhat distinct from those arising with local provision of higher education. These include the balance of local and foreign educational decision making and its implications for academic staff and for the learning experiences of students. This paper is informed by ‘Learning without Borders: Leadership in transnational education and internationalization of curriculum’, an Australian Office of Learning and Teaching (OLT) funded project undertaken at Curtin University and Swinburne University of Technology, involving Australian campuses and branch campuses. The project investigated staff experiences, expectations and preferences on TNE issues including career path opportunities, teaching and learning implications. The project focused particularly on the development of recognition and support for leadership roles in transnational education and on internationalization of curriculum. The paper highlights some of the TNE and internationalization measures that might enhance staff experiences and student learning
Ga2O3 polymorphs: Tailoring the epitaxial growth conditions
Gallium oxide is a wide bandgap n-type semiconductor highly interesting for optoelectronic applications (e.g., power electronics and solar blind UV photodetectors). Besides its most thermodynamically stable monoclinic β phase, Ga2O3 can crystallize in different polymorphs; among them the corundum α and the orthorhombic ϵ phases are the most promising ones. In this review we focus on the main aspects that promote the nucleation and stable growth of these Ga2O3 polymorphs. Particular emphasis is given to the ϵ phase since it is recently gaining increasing attention in the scientific community because of: (i) its higher lattice symmetry with respect to β-Ga2O3, which could favour the realization of heterostructures, (ii) the possibility to be grown on cheap sapphire substrates and (iii) its peculiar piezoelectric properties. While the growth of β-Ga2O3 is widely studied and understood, a thorough and comprehensive analysis of the chemical and physical aspects that allow for the stabilization of the metastable Ga2O3 phases with different synthesis methods is still missing. Therefore, the present review aims at filling this gap, by analysing the relevant growth parameters for several growth techniques (MOVPE, HVPE, mist-CVD, MBE, and PLD), highlighting similarities and differences, looking for a unified framework to understand the growth and nucleation of different Ga2O3 polymorphs. As a conclusion, we highlight practical guidelines for the deposition of the different Ga2O3 polymorphs with all the discussed thin film growth techniques
Performance or Marketing Benefits? The Case of LEED Certification
Green building adoption is driven by both performance-based benefits and marketing based benefits. Performance based benefits are those that improve performance or lower operating costs of the building or of building users. Marketing benefits stem from the consumer response to green certification. This study illustrates the relative importance of the marketing based benefits that accrue to Leadership in Energy and Environmental Design (LEED) buildings due to green signaling mechanisms, specifically related to the certification itself are identified. Of course, all participants in the LEED certification scheme seek marketing benefits. But even among LEED participants, the interest in green signaling is pronounced. The green signaling mechanism that occurs at the certification thresholds shifts building patterns from just below to just above the threshold level, and motivates builders to cluster buildings just above each threshold. Results are consistent across subsamples, though nonprofit organizations appear to build greener buildings and engage in more green signaling than for-profit entities. Using nonparametric regression discontinuity, signaling across different building types is observed. Marketing benefits due to LEED certification drives organizations to build “greener” buildings by upgrading buildings at the thresholds to reach certification levels
Evolutionary stability of antigenically escaping viruses
Antigenic variation is the main immune escape mechanism for RNA viruses like
influenza or SARS-CoV-2. While high mutation rates promote antigenic escape,
they also induce large mutational loads and reduced fitness. It remains unclear
how this cost-benefit trade-off selects the mutation rate of viruses. Using a
traveling wave model for the co-evolution of viruses and host immune systems in
a finite population, we investigate how immunity affects the evolution of the
mutation rate and other non-antigenic traits, such as virulence. We first show
that the nature of the wave depends on how cross-reactive immune systems are,
reconciling previous approaches. The immune-virus system behaves like a Fisher
wave at low cross-reactivities, and like a fitness wave at high
cross-reactivities. These regimes predict different outcomes for the evolution
of non-antigenic traits. At low cross-reactivities, the evolutionarily stable
strategy is to maximize the speed of the wave, implying a higher mutation rate
and increased virulence. At large cross-reactivities, where our estimates place
H3N2 influenza, the stable strategy is to increase the basic reproductive
number, keeping the mutation rate to a minimum and virulence low
Interrelationship between serum and sputum inflammatory mediators in chronic obstructive pulmonary disease
Little is known about airway inflammatory markers in chronic obstructive pulmonary disease (COPD). The objective of the present study was to identify and try to correlate pulmonary and peripheral blood inflammatory markers in COPD. In a cross-sectional study on patients with stable COPD, induced sputum and blood samples were collected for the determination of C-reactive protein, eosinophilic cationic protein, serum amyloid A protein, a-1 antitrypsin (a-1AT), and neutrophil elastase. Twenty-two patients were divided into two groups according to post-bronchodilator forced expiratory volume in the first second (%FEV1): group 1 (N = 12, FEV1 <40%) and group 2 (N = 10, FEV1 ³40%). An increase in serum elastase, eosinophilic cationic protein and a-1AT was observed in serum markers in both groups. Cytology revealed the same total number of cells in groups 1 and 2. There was a significantly higher number of neutrophils in group 1 compared to group 2 (P < 0.05). No difference in eosinophils or macrophages was observed between groups. Serum elastase was positively correlated with serum a-1AT (group 1, r = 0.81, P < 0.002 and group 2, r = 0.83, P < 0.17) and negatively correlated with FEV1 (r = -0.85, P < 0.03 and -0.14, P < 0.85, respectively). The results indicate the presence of chronic and persistent pulmonary inflammation in stable patients with COPD. Induced sputum permitted the demonstration of the existence of a subpopulation of cells in which neutrophils predominated. The serum concentration of all inflammatory markers did not correlate with the pulmonary functional impairment
Recommended from our members
Faceting and metal-exchange catalysis in (010) β-Ga2O3 thin films homoepitaxially grown by plasma-assisted molecular beam epitaxy
We here present an experimental study on (010)-oriented -Ga2O3 thin films homoepitaxially grown by plasma assisted molecular
beam epitaxy. We study the effect of substrate treatments (i.e., O-plasma and Ga-etching) and several deposition parameters
(i.e., growth temperature and metal-to-oxygen flux ratio) on the resulting Ga2O3 surface morphology and growth rate. In situ
and ex-situ characterizations identified the formation of (110) and (¯110)-facets on the nominally oriented (010) surface induced
by the Ga-etching of the substrate and by several growth conditions, suggesting (110) to be a stable (yet unexplored) substrate
orientation. Moreover, we demonstrate how metal-exchange catalysis enabled by an additional In-flux significantly increases the
growth rate (>threefold increment) of monoclinic Ga2O3 at high growth temperatures, while maintaining a low surface roughness
(rms < 0.5 nm) and preventing the incorporation of In into the deposited layer. This study gives important indications for
obtaining device-quality thin films and opens up the possibility to enhance the growth rate in -Ga2O3 homoepitaxy on different
surfaces [e.g., (100) and (001)] via molecular beam epitaxy
Your place or mine: transnational education and the locus of control
In transnational education the place – in both an organisational and a geographic sense – in which educational decisions are made impacts on the academics involved and on student learning. The subject of this paper is learning and accreditation that takes place outside a home university through offshore branch campuses. A case study of two Australian Universities with offshore campuses in Sarawak, Malaysia was undertaken. Policies and procedures were reviewed and an empirical study of the experiences of academics involved was conducted. The study focused on who makes decisions about curriculum content, learning and teaching activities, design and provision of educational resources, and the assessment of student work. Consequences of the organisational relationships for academics involved and for student learning are examined in this paper. On the basis of the study a high degree of local control is recommended, at least for units of study that have operated transnationally several times
Antimicrobial susceptibility to zinc bacitracin of Clostridium perfringens of rabbit origin
Zinc bacitracin is widely used in Italian rabbit farms to control both Epizootic Rabbit Enteropathy (ERE) and clostridiosis, and field results demonstrate useful activity. Nevertheless, data regarding the in vitro efficacy of zinc bacitracin against clostridia of rabbit origin are not available. In this study, the minimal inhibitory concentrations (MICs) of zinc bacitracin were evaluated in 123 C. perfringens strains isolated from rabbits in Italian fattening units. The agar dilution method was performed in Brucella Agar supplemented with laked sheep blood, haemin and vitamin K1, as recommended in NCCLS document M11-A6. Most strains (94.3%) had low MIC values (£ 0.5 mg/ml), and a few strains (4%) were inhibited by a concentration of 1 mg/ml. Two isolates (1.6%) had a MIC value of 16mg/ml. The MIC values of ATCC reference strains showed a good fit between each batch. MIC required to inhibit the 90% of organisms was 0.5 mg/ml and the presence of only two strains with MIC=16 mg/ml revealed the susceptibility to zinc bacitracin of Italian isolates of C. perfringens from rabbit and the absence of acquired resistance.Agnoletti, F.; Bacchin, C.; Bano, L.; Passera, A.; Favretti, M.; Mazzolini, E. (2007). Antimicrobial susceptibility to zinc bacitracin of Clostridium perfringens of rabbit origin. World Rabbit Science. 15(1):19-22. doi:10.4995/wrs.2007.609192215
Gene expression profiling reveals a conserved microglia signature in larval zebrafish
International audienceMicroglia are the resident macrophages of the brain. Over the past decade, our understanding of the function of these cells has significantly improved. Microglia do not only play important roles in the healthy brain but are involved in almost every brain pathology. Gene expression profiling allowed to distinguish microglia from other macro-phages and revealed that the full microglia signature can only be observed in vivo. Thus, animal models are irreplaceable to understand the function of these cells. One of the popular models to study microglia is the zebrafish larva. Due to their optical transparency and genetic accessibility, zebrafish larvae have been employed to understand a variety of microglia functions in the living brain. Here, we performed RNA sequencing of larval zebrafish microglia at different developmental time points: 3, 5, and 7 days post fertilization (dpf). Our analysis reveals that larval zebrafish microglia rapidly acquire the core microglia signature and many typical microglia genes are expressed from 3 dpf onwards. The majority of changes in gene expression happened between 3 and 5 dpf, suggesting that differentiation mainly takes place during these days. Furthermore, we compared the larval microglia transcriptome to published data sets of adult zebrafish microglia, mouse microglia, and human microglia. Larval microglia shared a significant number of expressed genes with their adult counterparts in zebrafish as well as with mouse and human microglia. In conclusion, our results show that larval zebrafish microglia mature rapidly and express the core microglia gene signature that seems to be conserved across species. K E Y W O R D S brain, evolution, microglia, RNA sequencing, transcriptome, zebrafis
Phase-selective growth of - vs -GaO and (InGa)O by In-mediated metal exchange catalysis in plasma-assisted molecular beam epitaxy
Its piezo- and potentially ferroelectric properties make the metastable kappa
polymorph of GaO an interesting material for multiple applications,
while In-incorporation into any polymorphs of GaO allows to lower their
bandgap. In this work, we provide a guideline to achieve single phase
-, -GaO as well as their (InGa)O
alloys up to x = 0.14 and x = 0.17 respectively, using In-mediated metal
exchange catalysis in plasma assisted molecular beam epitaxy (MEXCAT-MBE). The
polymorph transition from to is also addressed, highlighting
the fundamental role played by the thermal stability of the
-GaO. Additionally, we also demonstrate the possibility to grow
(01) -GaO on top of -AlO (0001) at
temperatures at least 100 {\deg}C above those achievable with conventional
non-catalyzed MBE, opening the road for increased crystal quality in
heteroepitaxy. The role of the substrate, as well as strain and structural
defects in the growth of -GaO is also investigated by growing
simultaneously on three different materials: (i) -AlO (0001),
(ii) 20 nm of (01) -GaO on -AlO (0001)
and (iii) (01) -GaO single crystal.Comment: Main text: 7 pages, 4 figures; Supplementary: 6 pages, 9 figure
- …