The N/O Plateau of Blue Compact Galaxies: Monte Carlo Simulations of the Observed Scatter

Chemical evolution models and Monte Carlo simulation techniques have been combined for the first time to study the distribution of blue compact galaxies on the N/O plateau. Each simulation comprises 70 individual chemical evolution models. For each model, input parameters relating to a galaxy's star formation history (bursting or continuous star formation, star formation efficiency), galaxy age, and outflow rate are chosen randomly from ranges predetermined to be relevant. Predicted abundance ratios from each simulation are collectively overplotted onto the data to test its viability. We present our results both with and without observational scatter applied to the model points. Our study shows that most trial combinations of input parameters, including a simulation comprising only simple models with instantaneous recycling, are successful in reproducing the observed morphology of the N/O plateau once observational scatter is added. Therefore simulations which include delay of nitrogen injection are no longer favored over those which propose that most nitrogen is produced by massive stars, if only the plateau morphology is used as the principal constraint. The one scenario which clearly cannot explain plateau morphology is one in which galaxy ages are allowed to range below 250 Myr. We conclude that the present data for the N/O plateau are insufficient by themselves for identifying the portion of the stellar mass spectrum most responsible for cosmic nitrogen production.Comment: 41 pages, 15 figures; accepted by ApJ, to appear Aug. 20, 200

Formation & evolution of the Galactic bulge: constraints from stellar abundances

We compute the chemical evolution of the Galactic bulge in the context of an inside-out model for the formation of the Milky Way. The model contains updated stellar yields from massive stars. The main purpose of the paper is to compare the predictions of this model with new observations of chemical abundance ratios and metallicity distributions in order to put constraints on the formation and evolution of the bulge. We computed the evolution of several alpha-elements and Fe and performed several tests by varying different parameters such as star formation efficiency, slope of the initial mass function and infall timescale. We also tested the effect of adopting a primary nitrogen contribution from massive stars. The [alpha/Fe] abundance ratios in the Bulge are predicted to be supersolar for a very large range in [Fe/H], each element having a different slope. These predictions are in very good agreement with most recent accurate abundance determinations. We also find a good fit of the most recent Bulge stellar metallicity distributions. We conclude that the Bulge formed on a very short timescale (even though timescales much shorter than about 0.1 Gyr are excluded) with a quite high star formation efficiency of about 20 Gyr$^{-1}$ and with an initial mass function more skewed toward high masses (i.e. x <= 0.95) than the solar neighbourhood and rest of the disk. The results obtained here are more robust than previous ones since they are based on very accurate abundance measurements.Comment: 26 pages, 9 figures, accepted for publication in A&

Barley beta-glucan promotes MnSOD expression and enhances angiogenesis under oxidative microenvironment

Manganese superoxide dismutase (MnSOD), a foremost antioxidant enzyme, plays a key role in angiogenesis. Barley-derived (1.3) β-d-glucan (β-d-glucan) is a natural water-soluble polysaccharide with antioxidant properties. To explore the effects of β-d-glucan on MnSOD-related angiogenesis under oxidative stress, we tested epigenetic mechanisms underlying modulation of MnSOD level in human umbilical vein endothelial cells (HUVECs) and angiogenesis in vitro and in vivo. Long-term treatment of HUVECs with 3% w/v β-d-glucan significantly increased the level of MnSOD by 200%&nbsp;±&nbsp;2% compared to control and by 50%&nbsp;±&nbsp;4% compared to untreated H2O2-stressed cells. β-d-glucan-treated HUVECs displayed greater angiogenic ability. In vivo, 24&nbsp;hrs-treatment with 3% w/v β-d-glucan rescued vasculogenesis in Tg (kdrl: EGFP) s843Tg zebrafish embryos exposed to oxidative microenvironment. HUVECs overexpressing MnSOD demonstrated an increased activity of endothelial nitric oxide synthase (eNOS), reduced load of superoxide anion (O2-) and an increased survival under oxidative stress. In addition, β-d-glucan prevented the rise of hypoxia inducible factor (HIF)1-α under oxidative stress. The level of histone H4 acetylation was significantly increased by β-d-glucan. Increasing histone acetylation by sodium butyrate, an inhibitor of class I histone deacetylases (HDACs I), did not activate MnSOD-related angiogenesis and did not impair β-d-glucan effects. In conclusion, 3% w/v β-d-glucan activates endothelial expression&nbsp;of MnSOD independent of histone acetylation level, thereby leading to adequate removal of O2-, cell survival and angiogenic response to&nbsp;oxidative stress. The identification of dietary β-d-glucan as activator of MnSOD-related angiogenesis might lead to the development of nutritional approaches for the prevention of ischemic remodelling and heart failure

Heavy element abundances in blue compact galaxies

We present high-quality ground-based spectroscopic observations of 54 supergiant H II regions in 50 low-metallicity blue compact galaxies with oxygen abundances 12 + log O/H between 7.1 and 8.3. We use the data to determine abundances for the elements N, O, Ne, S, Ar and Fe. We also analyze Hubble Space Telescope (HST) Faint Object Spectrograph archival spectra of 10 supergiant H II regions to derive C and Si abundances in a subsample of 7 BCGs. The main result of the present study is that none of the heavy element-to-oxygen abundance ratios studied here (C/O, N/O, Ne/O, Si/O, S/O, Ar/O, Fe/O) depend on oxygen abundance for BCGs with 12 + log O/H < 7.6 (Z < Zsun/20). This constancy implies that all these heavy elements have a primary origin and are produced by the same massive (M > 10Msun) stars responsible for O production. The dispersion of the C/O and N/O ratios in these galaxies is found to be remarkably small, being only +/-0.03 dex and +/-0.02 dex respectively. This very small dispersion is strong evidence against any time-delayed production of C and primary N in the lowest-metallicity BCGs (secondary N production is negligible at these low metallicities). The absence of a time-delayed production of C and N is consistent with the scenario that galaxies with 12 + log O/H < 7.6 are undergoing now their first burst of star formation, and that they are therefore young, with ages not exceeding 40 Myr. If very low metallicities BCGs are indeed young, this would argue against the commonly held belief that C and N are produced by intermediate-mass (3Msun < M < 9Msun) stars at very low metallicities, as these stars would not have yet completed their evolution in these lowest metallicity galaxies.Comment: 37 pages, 5 EPS figures, to appear in ApJ, February 199

Evolutionary Status of Dwarf ``Transition'' Galaxies

We present deep B, R and Halpha imaging of 3 dwarf galaxies: NGC3377A, NGC4286, and IC3475. Based on previous broadband imaging and HI studies, these mixed-morphology galaxies were proposed by Sandage & Hoffman (1991) to be, respectively, a gas-rich low surface brightness Im dwarf, a nucleated dwarf that has lost most of its gas and is in transition from Im to dS0,N, and the prototypical example of a gas-poor ``huge low surface brightness'' early-type galaxy. From the combination of our broadband and Halpha imaging with the published information on the neutral gas content of these three galaxies, we find that (1) NGC3377A is a dwarf spiral; (2) NGC3377A and NGC4286 have comparable amounts of ongoing star formation, as indicated by their Halpha emission, while IC3475 has no detected HII regions to a very low limit; (3) the global star formation rates are at least a factor of 20 below that of 30 Doradus for NGC3377A and NGC4286; (4) while the amount of star formation is comparable, the distribution of star forming regions is very different between NGC3377A and NGC4286; (5) given their current star formation rates and gas contents, both NGC3377A and NGC4286 can continue to form stars for more than a Hubble time; (6) both NGC3377A and NGC4286 have integrated total B-R colors that are redder than the integrated total B-R color for IC3475, and thus it is unlikely that either galaxy will ever evolve into an IC3475 counterpart; and (7) IC3475 is too blue to be a dE. We thus conclude that we have not identified potential precursors to galaxies such as IC3475, and unless signifcant changes occur in the star formation rates, neither NGC3377A nor NGC4286 will evolve into a dwarf elliptical or dwarf spheroidal within a Hubble time.Comment: 34 pages, 6 jpg figures, 3 postscript figures, and 4 tables, uses AASTeX, ApJ, in pres

On Dwarf Galaxies as the Source of Intracluster Gas

Recent observational evidence for steep dwarf galaxy luminosity functions in several rich clusters has led to speculation that their precursors may be the source of the majority of gas and metals inferred from intracluster medium (ICM) x-ray observations. Their deposition into the ICM is presumed to occur through early supernovae-driven winds, the resultant systems reflecting the photometric and chemical properties of the low luminosity dwarf spheroidals and ellipticals we observe locally. We consider this scenario, utilising a self-consistent model for spheroidal photo-chemical evolution and gas ejection via galactic superwinds. Insisting that post-wind dwarfs obey the observed colour-luminosity-metallicity relations, we conclude that the bulk of the ICM gas and metals does not originate within their precursors.Comment: 43 pages, 8 figures, LaTeX, also available at http://msowww.anu.edu.au/~gibson/publications.html, to appear in ApJ, Vol 473, 1997, in pres

Iron as a tracer in galaxy clusters and groups

Available X-ray data are collected and organized concerning the iron and gas content of galaxy clusters and groups, together with the optical luminosity, mass and iron abundance of cluster galaxies. Several astrophysical inferences are then drawn, including the evidence for rich clusters having evolved without much baryon exchange with their surrondings, and having experienced very similar star formation histories. Groups are much gas-poor compared to clusters, and appear instead to have shed a major fraction of their original cosmic share of baryons, which indicates that galaxy clusters cannot have formed by assembling groups similar to the present day ones. It is argued that this favors low-$\Omega$ universes, in which the growth of rich clusters is virtually complete at high redshifts. It is also argued that elemental abundance ratios in clusters are nearly solar, which is consistent with a similar proportion of supernovae of Type Ia and Type II having enriched both the solar neghborhood as well clusters as a whole. Much of the iron in clusters appears to reside in the intracluster medium rather than inside galaxies. It appears that the baryon to star conversion in clusters has been nearly as efficient as currently adopted for the universe as a whole. Yet the metallicity of the clusters is $\sim 5$ times higher than the global metallicity adopted for the nearby universe. It is concluded that the intergalactic medium should have a metallicity $\sim 1/3$ solar if stellar nucleosynthesis has proceeded in stars within field galaxies with the same efficiency as in stars within clusters of galaxies.Comment: AASTex Latex, 29 pages, 6 figure

Hypernovae/GRB in the Galactic Center as possible sources of Galactic Positrons

The observation of a strong and extended positron-electron line annihilation emission in the central regions of the Galaxy by INTEGRAL-SPI, consistent with the Galactic bulge geometry, without any counterpart in the gamma-ray range, neither at high energy nor in the 1809 keV $^{26}$Al decay line, is challenging. Leaving aside the geometrical question, we address the problem of the adequate positron sources, showing the potentiality of a new category of SN Ic, exemplified by SN2003dh, which is associated to a gamma-ray burst. This kind of supernova/hypernova/GRB event is interpreted as the result of a bipolar Wolf-Rayet explosion, which produces a large amount of $^{56}$Ni and ejects it at high velocity along the rotation axis. The bulk of positrons resulting from $^{56}$Co decay escapes in the surrounding medium due to the rapid thinning of the ejecta in the polar direction. We show that a rate of about 0.02 SN2003dh-like events per century in the central region of the Galaxy is sufficient to explain the positron flux detected by INTEGRAL-SPI. In order to explain this flux by SN Ia events alone, a rate of 0.5 per century is necessary, much higher than indicated by Galactic evolutionary models applied to the bulge. Further observations of late light curves of SNe Ia and SNe Ic in the bulge of spiral galaxies, together with 3D hydrodynamic calculations of anisotropic ejections of $^{56}$Ni in SN Ic/GRB events, will allow to estimate the separate contributions of SNe Ia and SNe Ic to positron injection.Comment: 7 pages, 0 figures, accepted for publication in Astrophysical Journal Letters, 2003 12 0

Dietary habits and nutritional biomarkers in Italian type 1 diabetes families: evidence of unhealthy diet and combined-vitamin-deficient intakes

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