Time of Arrival from Bohmian Flow

We develop a new conception for the quantum mechanical arrival time distribution from the perspective of Bohmian mechanics. A detection probability for detectors sensitive to quite arbitrary spacetime domains is formulated. Basic positivity and monotonicity properties are established. We show that our detection probability improves and generalises earlier proposals by Leavens and McKinnon. The difference between the two notions is illustrated through application to a free wave packet.Comment: 18 pages, 8 figures, to appear in Journ. Phys. A; representation of ref. 5 improved (thanks to Rick Leavens

CMA – a comprehensive Bioconductor package for supervised classification with high dimensional data

For the last eight years, microarray-based class prediction has been a major topic in statistics, bioinformatics and biomedicine research. Traditional methods often yield unsatisfactory results or may even be inapplicable in the p > n setting where the number of predictors by far exceeds the number of observations, hence the term “ill-posed-problem”. Careful model selection and evaluation satisfying accepted good-practice standards is a very complex task for inexperienced users with limited statistical background or for statisticians without experience in this area. The multiplicity of available methods for class prediction based on high-dimensional data is an additional practical challenge for inexperienced researchers. In this article, we introduce a new Bioconductor package called CMA (standing for “Classification for MicroArrays”) for automatically performing variable selection, parameter tuning, classifier construction, and unbiased evaluation of the constructed classifiers using a large number of usual methods. Without much time and effort, users are provided with an overview of the unbiased accuracy of most top-performing classifiers. Furthermore, the standardized evaluation framework underlying CMA can also be beneficial in statistical research for comparison purposes, for instance if a new classifier has to be compared to existing approaches. CMA is a user-friendly comprehensive package for classifier construction and evaluation implementing most usual approaches. It is freely available from the Bioconductor website at http://bioconductor.org/packages/2.3/bioc/html/CMA.html

Evaluating Microarray-based Classifiers: An Overview

For the last eight years, microarray-based class prediction has been the subject of numerous publications in medicine, bioinformatics and statistics journals. However, in many articles, the assessment of classification accuracy is carried out using suboptimal procedures and is not paid much attention. In this paper, we carefully review various statistical aspects of classifier evaluation and validation from a practical point of view. The main topics addressed are accuracy measures, error rate estimation procedures, variable selection, choice of classifiers and validation strategy

Non-realism : deep thought or a soft option ?

The claim that the observation of a violation of a Bell inequality leads to an alleged alternative between nonlocality and non-realism is annoying because of the vagueness of the second term.Comment: 5 page

Bohmian transmission and reflection dwell times without trajectory sampling

Within the framework of Bohmian mechanics dwell times find a straightforward formulation. The computation of associated probabilities and distributions however needs the explicit knowledge of a relevant sample of trajectories and therefore implies formidable numerical effort. Here a trajectory free formulation for the average transmission and reflection dwell times within static spatial intervals [a,b] is given for one-dimensional scattering problems. This formulation reduces the computation time to less than 5% of the computation time by means of trajectory sampling.Comment: 14 pages, 7 figures; v2: published version, significantly revised and shortened (former sections 2 and 3 omitted, appendix A added, simplified mathematics

Quasi-ballistic transport in HgTe quantum-well nanostructures

The transport properties of micrometer scale structures fabricated from high-mobility HgTe quantum-wells have been investigated. A special photoresist and Ti masks were used, which allow for the fabrication of devices with characteristic dimensions down to 0.45 $\mu$m. Evidence that the transport properties are dominated by ballistic effects in these structures is presented. Monte Carlo simulations of semi-classical electron trajectories show good agreement with the experiment.Comment: 3 pages, 3 figures; minor revisions: replaced "inelastic mean free path" with "transport mean free path"; corrected typing errors; restructered most paragraphs for easier reading; accepted for publication in AP

The Quantum Spin Hall Effect: Theory and Experiment

The search for topologically non-trivial states of matter has become an important goal for condensed matter physics. Recently, a new class of topological insulators has been proposed. These topological insulators have an insulating gap in the bulk, but have topologically protected edge states due to the time reversal symmetry. In two dimensions the helical edge states give rise to the quantum spin Hall (QSH) effect, in the absence of any external magnetic field. Here we review a recent theory which predicts that the QSH state can be realized in HgTe/CdTe semiconductor quantum wells. By varying the thickness of the quantum well, the band structure changes from a normal to an "inverted" type at a critical thickness $d_c$. We present an analytical solution of the helical edge states and explicitly demonstrate their topological stability. We also review the recent experimental observation of the QSH state in HgTe/(Hg,Cd)Te quantum wells. We review both the fabrication of the sample and the experimental setup. For thin quantum wells with well width $d_{QW}< 6.3$ nm, the insulating regime shows the conventional behavior of vanishingly small conductance at low temperature. However, for thicker quantum wells ($d_{QW}> 6.3$ nm), the nominally insulating regime shows a plateau of residual conductance close to $2e^2/h$. The residual conductance is independent of the sample width, indicating that it is caused by edge states. Furthermore, the residual conductance is destroyed by a small external magnetic field. The quantum phase transition at the critical thickness, $d_c= 6.3$ nm, is also independently determined from the occurrence of a magnetic field induced insulator to metal transition.Comment: Invited review article for special issue of JPSJ, 32 pages. For higher resolution figures see official online version when publishe