14 research outputs found
Ablation of TSC2 Enhances Insulin Secretion by Increasing the Number of Mitochondria through Activation of mTORC1
Get PDF) mice. The present study examines the effects of TSC2 ablation on insulin secretion from pancreatic beta cells. mice and TSC2 knockdown insulin 1 (INS-1) insulinoma cells treated with small interfering ribonucleic acid were used to investigate insulin secretion, ATP content and the expression of mitochondrial genes. mice exhibit hyperinsulinemia due to an increase in the number of mitochondria as well as enlargement of individual beta cells via activation of mTORC1.Activation of mTORC1 by TSC2 ablation increases mitochondrial biogenesis and enhances insulin secretion from pancreatic beta cells
Effect of dalteparin, a low-molecular-weight heparin, as adjunctive therapy in patients with Kawasaki disease: a retrospective study
No full textSpontaneous Occlusion of Ruptured Vertebral Artery Dissection at the Extradural Fenestration Associated with Extradural Origin of the Posterior Inferior Cerebellar Artery. Case Report.
No full textEffects of Hot Deformation and Subsequent Austempering on the Mechanical Properties of Si-Mn TRIP Steels
No full textButyrate-Producing Probiotics Reduce Nonalcoholic Fatty Liver Disease Progression in Rats: New Insight into the Probiotics for the Gut-Liver Axis
No full textA Dual Arylboronic Acid–Aminothiourea Catalytic System for the Asymmetric Intramolecular Hetero-Michael Reaction of α,β-Unsaturated Carboxylic Acids
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Analysis of Fume Formation Rate and Fume Particle Composition for Gas Metal Arc Welding (GMAW) of Plain Carbon Steel Using Different Shielding Gas Compositions
No full textRecent Advances in Ce-Based Heavy-Fermion Superconductivity and Fermi Surface Properties
No full textTomografia computadorizada de feixe cônico (Cone beam): entendendo este novo método de diagnóstico por imagem com promissora aplicabilidade na Ortodontia
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