Representation of second-order polarisation mode dispersion

A new expansion for the Jones matrix of a transmission medium is used to describe high-order polarisation dispersion. Each term in the expansion is characterised by a pair of principal states and the corresponding dispersion parameters. With these descriptors, a new expression for pulse deformation is derived and confirmed by simulation

Statistical determination of the length dependence of high-order polarization mode dispersion

We describe a method of characterizing high-order polarization mode dispersion (PMD).Using a new expansion to approximate the Jones matrix of a polarization-dispersive medium, we study the length dependence of high-order PMD to the fourth order. A simple rule for the asymptotic behavior of PMD for short and long fibers is found. It is also shown that, in long fibers (~1000 km), at 40 Gbits/s the third- and fourth-order PMD may become comparable to the second-order PMD

The Influence of Quadrature Errors on Isogeometric Mortar Methods

Mortar methods have recently been shown to be well suited for isogeometric analysis. We review the recent mathematical analysis and then investigate the variational crime introduced by quadrature formulas for the coupling integrals. Motivated by finite element observations, we consider a quadrature rule purely based on the slave mesh as well as a method using quadrature rules based on the slave mesh and on the master mesh, resulting in a non-symmetric saddle point problem. While in the first case reduced convergence rates can be observed, in the second case the influence of the variational crime is less significant

\u3ci\u3eIn Vitro and In Vivo\u3c/i\u3e Correlation of Skin and Cellular Responses to Nucleic Acid Delivery

Skin, the largest organ in the body, provides a passive physical barrier against infection and contains elements of the innate and adaptive immune systems. Skin consists of various cells, including keratinocytes, fibroblasts, endothelial cells and immune cells. This diversity of cell types could be important to gene therapies because DNA transfection could elicit different responses in different cell types. Previously, we observed the upregulation and activation of cytosolic DNA sensing pathways in several non-tumor and tumor cell types as well in tumors after the electroporation (electrotransfer) of plasmid DNA (pDNA). Based on this research and the innate immunogenicity of skin, we correlated the effects of pDNA electrotransfer to fibroblasts and keratinocytes to mouse skin using reverse transcription real-time PCR (RT-qPCR) and several types of protein quantification. After pDNA electrotransfer, the mRNAs of the putative DNA sensors DEAD (AspGlu-Ala-Asp) box polypeptide 60 (Ddx60), absent in melanoma 2 (Aim2), Z-DNA binding protein 1 (Zbp1), interferon activated gene 202 (Ifi202), and interferon-inducible protein 204 (Ifi204) were upregulated in keratinocytes, while Ddx60, Zbp1 and Ifi204 were upregulated in fibroblasts. Increased levels of the mRNAs and proteins of several cytokines and chemokines were detected and varied based on cell type. Mouse skin experiments in vivo confirmed our in vitro results with increased expression of putative DNA sensor mRNAs and of the mRNAs and proteins of several cytokines and chemokines. Finally, with immunofluorescent staining, we demonstrated that skin keratinocytes, fibroblasts and macrophages contribute to the immune response observed after pDNA electrotransfer

Development of an approximate method for quantum optical models and their pseudo-Hermicity

An approximate method is suggested to obtain analytical expressions for the eigenvalues and eigenfunctions of the some quantum optical models. The method is based on the Lie-type transformation of the Hamiltonians. In a particular case it is demonstrated that $E\times \epsilon$ Jahn-Teller Hamiltonian can easily be solved within the framework of the suggested approximation. The method presented here is conceptually simple and can easily be extended to the other quantum optical models. We also show that for a purely imaginary coupling the $E\times \epsilon$ Hamiltonian becomes non-Hermitian but $P\sigma _{0}$-symmetric. Possible generalization of this approach is outlined.Comment: Paper prepared fo the "3rd International Workshop on Pseudo-Hermitian Hamiltonians in Quantum Physics" June 2005 Istanbul. To be published in Czechoslovak Journal of Physic

Canonical description of ideal magnetohydrodynamic flows and integrals of motion

In the framework of the variational principle the canonical variables describing ideal magnetohydrodynamic (MHD) flows of general type (i.e., with spatially varying entropy and nonzero values of all topological invariants) are introduced. The corresponding complete velocity representation enables us not only to describe the general type flows in terms of single-valued functions, but also to solve the intriguing problem of the ``missing'' MHD integrals of motion. The set of hitherto known MHD local invariants and integrals of motion appears to be incomplete: for the vanishing magnetic field it does not reduce to the set of the conventional hydrodynamic invariants. And if the MHD analogs of the vorticity and helicity were discussed earlier for the particular cases, the analog of Ertel invariant has been so far unknown. It is found that on the basis of the new invariants introduced a wide set of high-order invariants can be constructed. The new invariants are relevant both for the deeper insight into the problem of the topological structure of the MHD flows as a whole and for the examination of the stability problems. The additional advantage of the proposed approach is that it enables one to deal with discontinuous flows, including all types of possible breaks.Comment: 16 page

An Improved Neutron Electric Dipole Moment Experiment

A new measurement of the neutron EDM, using Ramsey's method of separated oscillatory fields, is in preparation at the new high intensity source of ultra-cold neutrons (UCN) at the Paul Scherrer Institute, Villigen, Switzerland (PSI). The existence of a non-zero nEDM would violate both parity and time reversal symmetry and, given the CPT theorem, might lead to a discovery of new CP violating mechanisms. Already the current upper limit for the nEDM (|d_n|<2.9E-26 e.cm) constrains some extensions of the Standard Model. The new experiment aims at a two orders of magnitude reduction of the experimental uncertainty, to be achieved mainly by (1) the higher UCN flux provided by the new PSI source, (2) better magnetic field control with improved magnetometry and (3) a double chamber configuration with opposite electric field directions. The first stage of the experiment will use an upgrade of the RAL/Sussex/ILL group's apparatus (which has produced the current best result) moved from Institut Laue-Langevin to PSI. The final accuracy will be achieved in a further step with a new spectrometer, presently in the design phase.Comment: Flavor Physics & CP Violation Conference, Taipei, 200