149 research outputs found
SO(10) GUTs with gauge mediated supersymmetry breaking
We explore the phenomenology of supersymmetric SO(10) grand unified theories
with gauge mediated supersymmetry breaking. We show that if SO(10) breaking
proceeds through intermediate left-right symmetric gauge groups which are
broken at the supersymmetry breaking scale, then perturbative unification
allows the existence of only a few consistent models with very similar
phenomenological consequences. We list and discuss some distinctive signatures
of these theories. The most remarkable feature of the class of theories
introduced here is that, unlike in models with simpler symmetry breaking
chains, the allowed messenger spectrum is practically unique.Comment: 5 pages, no figures, uses REVTeX (replaced to match the version to be
published in PLB: some typos corrected and a reference updated, a minor
clarifying modification to the text
Synthesis of novel azo compounds containing 5(4H)-oxazolone ring as potent tyrosinase inhibitors
Six new azo dyes containing of 5(4H)-oxazolone ring were prepared by diazotization of 4-aminohippuric acid and coupling with N,N-dimethylaniline, 1-naphthol and 2-naphthol and condensation with 4-fluoro benzaldehyde or 4-trifluoromethoxy benzaldehyde. The new compounds were fully characterized by spectroscopic techniques. All synthesized compounds exhibited high tyrosinase inhibitory behavior. The results of mushroom tyrosinase inhibition assays indicate that the 4-trifluoromethoxy derivatives have high degrees of inhibition and N,N-dimethylaniline derivatives are better for tyrosinase inhibition than 1-naphthol and 2-naphthol derivatives. All synthesized azo compounds (4a-4f) showed the most potent mushroom tyrosinase inhibition, comparable to that of Kojic acid and l-mimosine, as reference standard inhibitors. © 2013 Elsevier Ltd. All rights reserved
Commensurate period Charge Density Modulations throughout the Pseudogap Regime
Theories based upon strong real space (r-space) electron electron
interactions have long predicted that unidirectional charge density modulations
(CDM) with four unit cell (4) periodicity should occur in the hole doped
cuprate Mott insulator (MI). Experimentally, however, increasing the hole
density p is reported to cause the conventionally defined wavevector of
the CDM to evolve continuously as if driven primarily by momentum space
(k-space) effects. Here we introduce phase resolved electronic structure
visualization for determination of the cuprate CDM wavevector. Remarkably, this
new technique reveals a virtually doping independent locking of the local CDM
wavevector at throughout the underdoped phase diagram of the
canonical cuprate . These observations have significant
fundamental consequences because they are orthogonal to a k-space (Fermi
surface) based picture of the cuprate CDM but are consistent with strong
coupling r-space based theories. Our findings imply that it is the latter that
provide the intrinsic organizational principle for the cuprate CDM state
Machine Learning in Electronic Quantum Matter Imaging Experiments
Essentials of the scientific discovery process have remained largely
unchanged for centuries: systematic human observation of natural phenomena is
used to form hypotheses that, when validated through experimentation, are
generalized into established scientific theory. Today, however, we face major
challenges because automated instrumentation and large-scale data acquisition
are generating data sets of such volume and complexity as to defy human
analysis. Radically different scientific approaches are needed, with machine
learning (ML) showing great promise, not least for materials science research.
Hence, given recent advances in ML analysis of synthetic data representing
electronic quantum matter (EQM), the next challenge is for ML to engage
equivalently with experimental data. For example, atomic-scale visualization of
EQM yields arrays of complex electronic structure images, that frequently elude
effective analyses. Here we report development and training of an array of
artificial neural networks (ANN) designed to recognize different types of
hypothesized order hidden in EQM image-arrays. These ANNs are used to analyze
an experimentally-derived EQM image archive from carrier-doped cuprate Mott
insulators. Throughout these noisy and complex data, the ANNs discover the
existence of a lattice-commensurate, four-unit-cell periodic,
translational-symmetry-breaking EQM state. Further, the ANNs find these
phenomena to be unidirectional, revealing a coincident nematic EQM state.
Strong-coupling theories of electronic liquid crystals are congruent with all
these observations.Comment: 44 pages, 15 figure
Consistency between ARPES and STM measurements on SmB
Strongly correlated topological surface states are promising platforms for
next-generation quantum applications, but they remain elusive in real
materials. The correlated Kondo insulator SmB is one of the most promising
candidates, with theoretically predicted heavy Dirac surface states supported
by transport and scanning tunneling microscopy (STM) experiments. However, a
puzzling discrepancy appears between STM and angle-resolved photoemission
(ARPES) experiments on SmB. Although ARPES detects spin-textured surface
states, their velocity is an order of magnitude higher than expected, while the
Dirac point -- the hallmark of any topological system -- can only be inferred
deep within the bulk valence band. A significant challenge is that SmB
lacks a natural cleavage plane, resulting in ordered surface domains limited to
10s of nanometers. Here we use STM to show that surface band bending can shift
energy features by 10s of meV between domains. Starting from our STM spectra,
we simulate the full spectral function as an average over multiple domains with
different surface potentials. Our simulation shows excellent agreement with
ARPES data, and thus resolves the apparent discrepancy between large-area
measurements that average over multiple band-shifted domains and
atomically-resolved measurements within a single domain
Bounds on R-Parity Violating Parameters from Fermion EDM's
We study one-loop contributions to the fermion electric dipole moments in the
Minimal Supersymmetric Standard Model with explicit R-parity violating
interactions. We obtain new individual bounds on R-parity violating Yukawa
couplings and put more stringent limits on certain parameters than those
obtained previously.Comment: 16 pages, LaTe
Gauged Yukawa Matrix Models and 2-Dimensional Lattice Theories
We argue that chiral symmetry breaking in three dimensional QCD can be
identified with N\'eel order in 2-dimensional quantum antiferromagnets. When
operators which drive the chiral transition are added to these theories, we
postulate that the resulting quantum critical behavior is in the universality
class of gauged Yukawa matrix models. As a consequence, the chiral transition
is typically of first order, although for a limited class of parameters it can
be second order with computable critical exponents.Comment: LaTeX, 11 page
Genomic and phenotypic analyses of diverse non-clinical Acinetobacter baumannii strains reveals strain-specific virulence and resistance capacity.
Acinetobacter baumannii is a critically important pathogen known for its widespread antibiotic resistance and ability to persist in hospital-associated environments. Whilst the majority of A. baumannii infections are hospital-acquired, infections from outside the hospital have been reported with high mortality. Despite this, little is known about the natural environmental reservoir(s) of A. baumannii and the virulence potential underlying non-clinical strains. Here, we report the complete genome sequences of six diverse strains isolated from environments such as river, soil, and industrial sites around the world. Phylogenetic analyses showed that four of these strains were unrelated to representative nosocomial strains and do not share a monophyletic origin, whereas two had sequence types belonging to the global clone lineages GC1 and GC2. Further, the majority of these strains harboured genes linked to virulence and stress protection in nosocomial strains. These genotypic properties correlated well with in vitro virulence phenotypic assays testing resistance to abiotic stresses, serum survival, and capsule formation. Virulence potential was confirmed in vivo, with most environmental strains able to effectively kill Galleria mellonella greater wax moth larvae. Using phenomic arrays and antibiotic resistance profiling, environmental and nosocomial strains were shown to have similar substrate utilisation patterns although environmental strains were distinctly more sensitive to antibiotics. Taken together, these features of environmental A. baumannii strains suggest the existence of a strain-specific distinct gene pools for niche specific adaptation. Furthermore, environmental strains appear to be equally virulent as contemporary nosocomial strains but remain largely antibiotic sensitive
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