A fuzzy logic model for the analysis of social corporate responsibility

Introduction: Critical public opinion, based on information that is made available to the public through different systems, has led companies that operate in the environment to continually improve their social, environmental, and ethical performance. Objectives: This paper aims to propose a fuzzy-logic-based model for the analysis of social corporate responsibility in cases of environmental accidents. Methods: Our study employs techniques derived from social network analysis. The data was collected from the online database of The New York Times for the timespan from March 24, 1989, to September 1, 2017. Results: The results show that the proposed model can be replicated, after some adjustments. Conclusion: We conclude that, despite the complexity of an analysis of this kind in which the model is applied considering isolated words in the text and not the semantic aspects, the proposed model based on fuzzy logic is adequate for the analysis of social corporate responsibility.We would like to thank professors Mariana Claudia Broens, Jose Arthur Quilici Gonzalez and Maria Eunice Quilici Gonzalez for the helpful supervision and indications during the fundamental stages of this research. This paper was supported by the "Understanding opinion and language dynamics using massive data", funded by The São Paulo Research Foundation - FAPESP (reference: 2016/50256-0) (Trans-Atlantic Platform Social Sciences and Humanities, Digging into Data Challenges). We would like to thank the whole team of this project for their discussion and feedback. Ana Claudia Golzio also received support by FAPESP (process number: 2019/08442-9) during the development of this paper, and Mirelys Puerta-Díaz received funding from Coordination for the Improvement of Higher Education Personnel (CAPES) - Financial Code 001

Post-pulse addition of trans-cyclohexane-1,2-diol improves electrotransfer mediated gene expression in mammalian cells

AbstractElectric field mediated gene transfer is facing a problem in expression yield due to the poor transfer across the nuclear envelope. Trans-cyclohexane-1,2-diol (TCHD) was shown to significantly increase chemically mediated transfection by collapsing the permeability barrier of the nuclear pore complex. We indeed observed a significant increase in expression by electrotransfer when cells are treated post pulse by a low non toxic concentration of TCHD. This was obtained for different pulsing conditions, cell strains and plasmid constructs. An interesting improvement in cell viability can be obtained. This can significantly enhance the non-viral gene electrical delivery