Madrid: Literary Fiction and the Imaginary Urban Destination

This study selects novels from French and Spanish language traditions, which may not be available to English-speakers, in order to determine if specific aspects throw light on our understanding of Madrid as a destination. Marc Lambron's L'Impromptu de Madrid and Antonio Munoz Molina’s Mysteries of Madrid are taken as proof of the influence the narrative can exert on social daily life and consumption. Narrative foregrounds the fictions which are at stake in imagining the city as destination and also provides a vehicle for presenting the much broader social forces that converge in the author at the time of imagining and writing

Evaluation of fixed sources of variation and estimation of genetic parameters for incidence of bovine respiratory disease in preweaned calves and feedlot cattle

The primary objective of this study was to estimate variance components and heritability of bovine respiratory disease (BRD) incidence in beef calves before weaning and during the finishing phase. The second objective was to investigate the impact of BRD incidence and treatment frequency on performance and carcass traits. Bovine respiratory disease is the biggest and most costly health challenge facing the cattle industry. The 2 populations used consisted of 1,519 preweaned calves and 3,277 head of feedlot cattle. The incidence rate of BRD in preweaned calves was 11.39%, and among treated cattle, 82.1% were treated once, 13.9% were treated twice, and 4.0% were treated 3 times or more. The incidence of BRD (P = 0.35) and the number of treatments (P = 0.77) had no significant effect on weaning BW. Heritability estimates of the entire preweaned population for BRD resistance and number of treatments were 0.11 ± 0.06 and 0.08 ± 0.05, respectively. The genetic correlation estimates for BRD incidence with weaning BW and birth BW were low (−0.02 ± 0.32 and 0.07 ± 0.27, respectively). The same estimate for the number of BRD treatments with weaning BW and birth BW was 0.25 ± 0.35 and 0.30 ± 0.27, respectively. The observed BRD incidence rate for feedlot cattle was observed at 9.43%. Incidence of BRD significantly (P \u3c 0.01) decreased overall and acclimation ADG by 0.06 ± 0.01 kg/d and 0.28 ± 0.03 kg/d, respectively. Carcass traits were also significantly (P \u3c 0.05) affected by BRD incidence; untreated cattle had a 9.1 ± 1.7-kg heavier HCW. Results were similar in the analysis of treatment frequency. The heritability estimate of BRD incidence and the number of treatments were 0.07 ± 0.04 and 0.02 ± 0.03, respectively. Estimates of genetic correlations of BRD incidence with production traits were −0.63 ± 0.22 for acclimation ADG, −0.04 ± 0.23 for on-test ADG, −0.31 ± 0.21 for overall ADG, −0.39 ± 0.21 for final BW, −0.22 ± 0.22 for HCW, −0.03 ± 0.22 for LM area, 0.24 ± 0.25 for fat, and −0.43 ± 0.20 for marbling score. Similar results for the number of treatments and production traits were −1.00 ± 0.68 for acclimation ADG, −0.04 ± 0.39 for on-test ADG, −0.47 ± 0.41 for overall ADG, −0.66 ± 0.40 for final BW, −0.58 ± 0.45 for HCW, −0.12 ± 0.38 for LM area, 0.42 ± 0.50 for fat, and −0.32 ± 0.37 for marbling score. Because of the high economic cost associated with BRD incidence, even these modest estimates for heritability of BRD resistance should be considered for incorporation into beef cattle breeding programs

Genome-Wide snp analysis of southern african populations provides new insights into the dispersal of bantu-Speaking groups

The expansion of Bantu-speaking agropastoralist populations had a great impact on the genetic, linguistic, and cultural variation of sub-Saharan Africa. It isgenerally accepted that Bantulanguages originated inanarea around thepresent borderbetweenCameroon and Nigeria approximately 5,000 years ago, from where they spread South and East becoming the largest African linguistic branch. The demic consequences of this event are reflected in the relatively high genetic homogeneity observed acrossmost of sub-Saharan Africapopulations. Inthiswork, weexploredgenome-wide singlenucleotidepolymorphismdata from28populations to characterize the genetic components present in sub-Saharan African populations. Combining novel data from four SouthernAfrican populations withpreviouslypublishedresults,we reject the hypothesis that the" non-Bantu" geneticcomponent reported inSouth-Eastern Africa (Mozambique) reflects extensive gene flow between incoming agriculturalist and resident hunter-gatherer communities.We alternatively suggest that this novel component is the result of demographic dynamics associated with the Bantu dispersal

Complex ancient genetic structure and cultural transitions in Southern African populations

The characterization of the structure of southern African populations has been the subject of numerous genetic, medical, linguistic, archaeological, and anthropological investigations. Current diversity in the subcontinent is the result of complex events of genetic admixture and cultural contact between early inhabitants and migrants that arrived in the region over the last 2000 years. Here, we analyze 1856 individuals from 91 populations, comprising novel and published genotype data, to characterize the genetic ancestry profiles of 631 individuals from 51 southern African populations. Combining both local ancestry and allele frequency based analyses, we identify a tripartite, ancient, Khoesan-related genetic structure. This structure correlates neither with linguistic affiliation nor subsistence strategy, but with geography, revealing the importance of isolation-by-distance dynamics in the area. Fine-mapping of these components in southern African populations reveals admixture and cultural reversion involving several Khoesan groups, and highlights that Bantu speakers and Coloured individuals have different mixtures of these ancient ancestries

Effects of a prolonged standardized diet on normalizing the human metabolome

Background: Although the effects of acute dietary interventions on the human metabolome have been studied, the extent to which the metabolome can be normalized by extended dietary standardization has not yet been examined

A taxonomic and phylogenetic revision of Penicillium section Aspergilloides

AbstractSpecies belonging to Penicillium section Aspergilloides have a world-wide distribution with P. glabrum, P. spinulosum and P. thomii the most well-known species of this section. These species occur commonly and can be isolated from many substrates including soil, food, bark and indoor environments. The taxonomy of these species has been investigated several times using various techniques, but species delimitation remains difficult. In the present study, 349 strains belonging to section Aspergilloides were subjected to multilocus molecular phylogenetic analyses using partial β-tubulin (BenA), calmodulin (CaM) and RNA polymerase II second largest subunit (RPB2) sequences. Section Aspergilloides is subdivided into 12 clades and 51 species. Twenty-five species are described here as new and P. yezoense, a species originally described without a Latin diagnosis, is validated. Species belonging to section Aspergilloides are phenotypically similar and most have monoverticillate conidiophores and grow moderately or quickly on agar media. The most important characters to distinguish these species were colony sizes on agar media, growth at 30 °C, ornamentation and shape of conidia, sclerotium production and stipe roughness