4 research outputs found
LTCC technology as a platform for the realization of fluidic microstructures for biological applications
No full textCharacterization of coumarin-6 polycrystalline films growth from vacuum deposition at various substrate temperatures
No full textMitochondrial potential (ΔΨm changes in single rat hepatocytes: The effect of orthovanadate nanoparticles doped with rare-earth elements
No full textNanoformulations for drug delivery: safety, toxicity, and efficacy
No full textThis chapter presents an outline of the recent available information regarding safety, toxicity, and efficacy of nano drug delivery systems. Of particular importance is the evaluation of several key factors to design nontoxic and effective nanoformulations. Among them, we focus on nanostructure materials and synthesis methods, mechanisms of interactions with biological systems, treatment of nanoparticles, manufacture impurities, and nanostability. Emphasis is given to in silico, in vitro, and in vivo models used to assess and predict the toxicity of these new formulations. Additionally, some examples of in vitro and in vivo studies of specific nanoderivatives are also presented in this chapter
