30 research outputs found
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Prospective Analysis of Heart Biopsies in Coronary Artery Surgery
In a prospective analysis of 36 biopsies from human hearts performed at the time of elective coronary operation, several morphological changes were identified in the myocardium. Some of these changes (fibrosis, vacuolation, edema, and amyloid deposition) are of clinical significance and may affect the long-term prognosis for patients undergoing revascularization procedures. It appears, therefore, that knowledge of the morphological state of the myocardium at the time of operation can prove useful in elucidating further the long-term effects of coronary artery bypass on the left ventricular myocardium
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Is cardioplegic rearrest safe?
In cardiac bypass procedures the use of anoxic arrest or ventricular fibrillation is known to cause severe myocardial damage. The authors have investigated the safety of using cardioplegic rearrest when surgical difficulties are encountered at the end of cardiac bypass procedure after cardioplegic arrest and reperfusion of the myocardium. From their clinical experience with 12 patients and laboratory experience with 13 pigs the authors conclude that although cardioplegic rearrest is not ideal it can be used safely in this situation
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Hemolysis during pulsatile perfusion: Clinical evaluation of a new device
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Hypertension after coronary operation. Can it be prevented by pulsatile perfusion?
Nonpulsatile perfusion during cardiopulmonary bypass (CPB) has been implicated as a causative factor of postoperative hypertension. In a consecutive series, patients undergoing coronary bypass were selected for perfusion with either nonpulsatile flow (American Optical roller pump) or pulsatile flow (Desjardin's modification of the roller pump). The incidence of postoperative hypertension and the levels of peripheral renin were noted. No differences could be observed in renin activity, with either modality of perfusion, before CPB, after 30 minutes of stable CPB, or 2 hours postoperatively. Hypertension, necessitating treatment, occurred in 60% of the patients having pulsatile and 68% of those having nonpulsatile perfusion (p less than 0.05). Although pulsatile CPB would appear to be more physiological than nonpulsatile perfusion, this method of creating pulsatile flow does not appear to eliminate postoperative hypertension
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INHALATION OF FOREIGN-BODIES BY CHILDREN - CONTINUING CHALLENGE IN MANAGEMENT
Surface nanostructuring for improved resolution in surface plasmon resonance imaging
International audienc
Surface nanostructuring for improved resolution in surface plasmon resonance imaging
International audienc
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Intraoperative transmural myocardial biopsy: a simple technique
A Tru-cut disposable biopsy needle was used in 10 pigs, 3 cadavers and 63 humans to obtain transmural ventricular myocardium for diagnostic and research purposes. The technique proved simple and safe. In every case an adequate amount of full-thickness myocardium was obtained which was examined by light and electron microscopy and used for enzyme studies and glycogen measurement