846 research outputs found

    Alien Registration- Castonguay, Alice M. (Orono, Penobscot County)

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    https://digitalmaine.com/alien_docs/5670/thumbnail.jp

    A note on the convexity number for complementary prisms

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    In the geodetic convexity, a set of vertices SS of a graph GG is convex\textit{convex} if all vertices belonging to any shortest path between two vertices of SS lie in SS. The cardinality con(G)con(G) of a maximum proper convex set SS of GG is the convexity number\textit{convexity number} of GG. The complementary prism\textit{complementary prism} GG‟G\overline{G} of a graph GG arises from the disjoint union of the graph GG and G‟\overline{G} by adding the edges of a perfect matching between the corresponding vertices of GG and G‟\overline{G}. In this work, we we prove that the decision problem related to the convexity number is NP-complete even restricted to complementary prisms, we determine con(GG‟)con(G\overline{G}) when GG is disconnected or GG is a cograph, and we present a lower bound when diam(G)≠3diam(G) \neq 3.Comment: 10 pages, 2 figure

    Alien Registration- Castonguay, Louis M. (Brunswick, Cumberland County)

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    https://digitalmaine.com/alien_docs/23462/thumbnail.jp

    Effects of Geochemical and Environmental Parameters on Abiotic Organic Chemistry Driven by Iron Hydroxide Minerals

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    Geological conditions play a significant role in prebiotic/abiotic organic chemistry, especially when reactive minerals are present. Previous studies of the prebiotic synthesis of amino acids and other products in mineral‐containing systems have shown that a diverse array of compounds can be produced, depending on the experimental conditions. However, these previous experiments have not simulated the effects of varying geochemical conditions, in which factors such as pH, iron redox state, or chemical concentrations may vary over time and space in a natural environment. In geochemical systems that contain overlapping gradients, many permutations of individual conditions could exist and affect the outcome of an organic reaction network. We investigated reactions of pyruvate and glyoxylate, two compounds that are central to the emergence of metabolism, in simulated geological gradients of redox, pH, and ammonia concentration. Our results show that the positioning of pyruvate/glyoxylate reactions in this environmental parameter space determines the organic product distribution that results. Therefore, the distribution pattern of amino acids and alpha‐hydroxy acids produced prebiotically in a system reflects the specific reaction conditions, and would be distinct at various locations in an environment depending on local geochemistry. This is significant for origin of life chemistry in which the composition and function of oligomers could be affected by the environmentally driven distribution of monomers available. Also, for astrobiology and planetary science where organic distribution patterns are sometimes considered as a possible biosignature, it is important to consider environmentally driven abiotic organic reactions that might produce similar effects

    Mott Transition, Compressibility Divergence and P-T Phase Diagram of Layered Organic Superconductors: An Ultrasonic Investigation

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    The phase diagram of the organic superconductor Îș\kappa-(BEDT-TTF)2_2Cu[N(CN)2_2Cl has been investigated by ultrasonic velocity measurements under helium gas pressure. Different phase transitions were identified trough several elastic anomalies characterized from isobaric and isothermal sweeps. Our data reveal two crossover lines that end on the critical point terminating the first-order Mott transition line. When the critical point is approached along these lines, we observe a dramatic softening of the velocity which is consistent with a diverging compressibility of the electronic degrees of freedom.Comment: 4 pages, 5 figure

    Rapid quantitative assays for glucose-6-phosphate dehydrogenase (G6PD) and hemoglobin combined on a capillary-driven microfluidic chip

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    Rapid tests for glucose-6-phosphate dehydrogenase (G6PD) are extremely important for determining G6PD deficiency, a widespread metabolic disorder which triggers hemolytic anemia in response to primaquine and tafenoquine medication, the most effective drugs for the radical cure of malaria caused by Plasmodium parasites. Current point-of-care diagnostic devices for G6PD are either qualitative, do not normalize G6PD activity to the hemoglobin concentration, or are very expensive. In this work we developed a capillary-driven microfluidic chip to perform a quantitative G6PD test and a hemoglobin measurement within 2 minutes and using less than 2 ÎŒL of sample. We used a powerful microfluidic module to integrate and resuspend locally the reagents needed for the G6PD assay and controls. We also developed a theoretical model that successfully predicts the enzymatic reactions on-chip, guides on-chip reagent spotting and allows efficient integration of multiple assays in miniaturized formats with only a few nanograms of reagents

    The Roles of Negative Affect and Goal Adjustment Capacities in Breast Cancer Survivors: Associations With Physical Activity and Diurnal Cortisol Secretion

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    Objective: This study examined whether within-person changes of breast cancer survivors’ high-arousal negative affect (e.g., feeling scared, upset, anxious, or guilty) could predict high levels of diurnal cortisol secretion and moderate-to-vigorous physical activity (MVPA). In addition, goal adjustment capacities (goal disengagement and goal reengagement) were expected to buffer the effect of negative affect on cortisol and to increase its effect on MVPA. Methods: High-arousal negative affect, self-reported MVPA, area-under-the-curve of diurnal cortisol secretion, and goal adjustment capacities were assessed in a longitudinal sample of 145 female breast cancer survivors. Results: Based on hierarchical linear modeling, breast cancer survivors reported increased levels of both MVPA and cortisol secretion if they experienced higher (as compared to lower) levels of high-arousal negative affect than their personal average. Furthermore, within-person negative affect was associated with: (i) higher MVPA among participants with high (but not low) goal reengagement capacities, and (ii) elevated cortisol secretion among participants with low (but not high) goal reengagement capacities. Conclusions: High-arousal negative affect may exert differing functions among breast cancer survivors in that it can trigger adaptive health behaviors, yet simultaneously elevate diurnal cortisol secretion. In addition, being able to engage in new goals may be a necessary condition for breast cancer survivors to experience the beneficial behavioral effects of high-arousal negative affect, and it may prevent the adverse effect of negative affect on enhanced cortisol output

    Evidence of Late Ediacaran Hyperextension of the Laurentian Iapetan Margin in the Birchy Complex, Baie Verte Peninsula, Northwest Newfoundland: Implications for the Opening of Iapetus, Formation of PeriLaurentian Microcontinents and Taconic – Grampian Orogenesis

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    The Birchy Complex of the Baie Verte Peninsula, northwestern Newfoundland, comprises an assemblage of mafic schist, ultramafic rocks, and metasedimentary rocks that are structurally sandwiched between overlying ca. 490 Ma ophiolite massifs of the Baie Verte oceanic tract and underlying metasedimentary rocks of the Fleur de Lys Supergroup of the Appalachian Humber margin. Birchy Complex gabbro yielded a Late Ediacaran U–Pb zircon ID–TIMS age of 558.3 ± 0.7 Ma, whereas gabbro and an intermediate tuffaceous schist yielded LA–ICPMS concordia zircon ages of 564 ± 7.5 Ma and 556 ± 4 Ma, respectively. These ages overlap the last phase of rift-related magmatism observed along the Humber margin of the northern Appalachians (565–550 Ma). The associated ultramafic rocks were exhumed by the Late Ediacaran and shed detritus into the interleaved sedimentary rocks. Psammite in the overlying Flat Point Formation yielded a detrital zircon population typical of the Laurentian Humber margin in the northern Appalachians. Age relationships and characteristics of the Birchy Complex and adjacent Rattling Brook Group suggest that the ultramafic rocks represent slices of continental lithospheric mantle exhumed onto the seafloor shortly before or coeval with magmatic accretion of mid-ocean ridge basalt-like mafic rocks. Hence, they represent the remnants of an ocean – continent transition zone formed during hyperextension of the Humber margin prior to establishment of a mid-ocean ridge farther outboard in the Iapetus Ocean. We propose that microcontinents such as Dashwoods and the Rattling Brook Group formed as a hanging wall block and an extensional crustal allochthon, respectively, analogous to the isolation of the Briançonnais block during the opening of the Alpine Ligurian–Piemonte and Valais oceanic seaways.Le complexe de Birchy de la pĂ©ninsule de Baie Verte, dans le nord-ouest de Terre-Neuve, est constituĂ© d’un assemblage de schistes mafiques, de roches ultramafiques et de mĂ©tasĂ©diments qui sont coincĂ©s entre des massifs ophiolitiques d’ascendance ocĂ©anique de la Baie Verte au-dessus, et des mĂ©tasĂ©diments du Supergroupe de Fleur de Lys de la marge de Humber des Appalaches en-dessous. Le complexe de gabbro de Birchy a donnĂ© une datation U-Pb sur zircon ID-TIMS correspondant Ă  la fin de l’Édiacarien, soit 558,3 ± 0,7 Ma, alors qu’un gabbro et un schiste tufacĂ© intermĂ©diaire montrent une datation LA-ICP-MS Concordia sur zircon de 564 ± 7,5 Ma et 556 ± 4 Ma, respectivement. Ces datations chevauchent la derniĂšre phase de magmatisme de rift observĂ©e le long de la marge Humber des Appalaches du Nord (565-550 Ma). Les roches ultramafiques associĂ©es ont Ă©tĂ© exhumĂ©es vers la fin de l’Édiacarien et leurs dĂ©bris ont Ă©tĂ© imbriquĂ©s dans des roches sĂ©dimentaires. Les psammites de la Formation de Flat Point susjacente ont donnĂ© une population de zircons dĂ©tritiques typique de la marge laurentienne de Humber des Appalaches du Nord. Les relations chronologiques et les caractĂ©ristiques du complexe de Birchy et du groupe de Rattling Brook adjacent, permettent de penser que ces roches ultramafiques pourraient ĂȘtre des Ă©cailles de manteau lithosphĂ©rique continental qui auraient Ă©tĂ© exhumĂ©es sur le plancher ocĂ©anique peu avant ou en mĂȘme temps que l’accrĂ©tion magmatique de roches mafiques basaltiques de type dorsale mĂ©dio-ocĂ©anique. Par consĂ©quent, elles seraient des vestiges d’une zone de transition ocĂ©an-continent formĂ©e au cours de l’hyper-extension de la marge de Humber avant l’apparition d’une dorsale mĂ©dio-ocĂ©anique plus loin au large dans l’ocĂ©an IapĂ©tus. Nous proposons que des microcontinents comme de Dashwoods et du groupe de Rattling Brook ont constituĂ©s respectivement un bloc de toit et un allochtone crustal d’extension, de la mĂȘme maniĂšre que le bloc Briançonnais a Ă©tĂ© isolĂ© lors de l’ouverture des bras ocĂ©aniques alpins de Ligurie-PiĂ©mont et de Valais.Fil: Van Staal, Cees R.. Geological Survey of Canada; CanadĂĄFil: Chew, Dave M.. Trinity College Dublin; IrlandaFil: Zagorevski, Alexandre. Geological Survey of Canada; CanadĂĄFil: Mcnicoll, Vicki. Geological Survey of Canada; CanadĂĄFil: Hibbard, James. North Carolina State University; Estados UnidosFil: Skulski, Tom. Geological Survey of Canada; CanadĂĄFil: Castonguay, SĂ©bastien. Geological Survey of Canada; CanadĂĄFil: Escayola, Monica Patricia. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas; Argentina. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas. Oficina de CoordinaciĂłn Administrativa Ciudad Universitaria. Instituto de Estudios Andinos; ArgentinaFil: Sylvester, Paul J.. Memorial University Of Newfoundland; Canad
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