5 research outputs found
Elucidation of transformation pathway of ketoprofen, ibuprofen, and furosemide in surface water and their occurrence in the aqueous environment using UHPLC-QTOF-MS
Isolation and identification of natural dyestuffs present in artistic paints and textiles of historical origin
Natural organic dyes are group of substances that belong to various
types of chemical compounds. The most commonly used in paintings and
dyeing textiles were naturally occurring dyestuffs from group of anthraquinones,
flavones and indigoid dyes. Identification of coloring substances
present in historical artistic paints provides relevant information for a wide
range of specialists dealing with works of art and in the field of conservation
science. This research presents a review of analytical techniques
(mainly chromatographic and spectroscopic) used for identification of
dyes. It also describes the methods of colorants isolation from historical
artistic paints and textiles. Furthermore, the article presents a brief characteristics
of fragmentation reactions of selected groups of dyestuffs, which is
useful in their identification
Types of chiral stationary phases and its applications to liquid chromatography (LC) – a mini review
Chromatograficzne rozdzielanie związków optycznie czynnych ma ogromne znaczenie nie tylko w przemyśle farmaceutycznym, ale i agrochemicznym, a także w badaniach naukowych różnego rodzaju. W niniejszym opracowaniu scharakteryzowano komercyjnie dostępne chiralne fazy stacjonarne na bazie, cyklodekstryn, polisacharydów, makrocyklicznych antybiotyków, eterów koronowych, a także fazy proteinowe, ligandowymienne, jonowymienne oraz fazy typu Pirkle’a. Omówiono podstawowe właściwości fizyczne i chemiczne w/w faz stacjonarnych, przedstawiono przykładowe ich struktury, mechanizmy chiralnego rozpoznania oraz podstawowe zastosowania. Opisano również warunki chromatograficznego rozdzielania chiralnego dla wybranych farmaceutyków i pestycydów.Importance of chromatographic enantioseparations in the pharmaceutical and agrochemical industries is still increasing. In this paper the chiral stationary phases, including cyclodextrins, polysaccharides, macrocyclic antibiotics, crown ethers, proteins, ligand-exchange, Pirkle-type and ion exchange phases is discussed. For all types of chiral stationary phases, the basic physical and chemical properties are discussed, as well as the structure and the possible chiral recognition mechanisms. The basic applications of this phases are also described. Chromatographic conditions for chiral separation of selected active pharmaceutical ingredients and pesticides are reviewed