354 research outputs found
Microaggressions and intercultural competence in the Spanish classroom
Microaggressions are subtle offensive mechanisms that can be intentional or unintentional (Pierce, 1970). For the past 50 years, researchers have documented their damaging effects on peoplesâ mental and physical health. In this report, we focus on microaggressions in the Spanish classroom and with Latino/Latinx/Hispanic students, including their damaging effects within the context of changing demographics in the United States, how they impact our language classrooms, and how they can be mitigated through language curricula that promote intercultural citizenship. Also, we share strategies and suggestions to counter microaggressions in the language classroom, grounded in the assumption that to support socially just learning environments, educators must create a healthy atmosphere where all students feel safe, respected, and validated, and are held to high academic and civic standards. We believe that language teachers are uniquely positioned to create learning environments that model intercultural perspectives and foster the necessary openness to analyze and understand different perspectives as students advance their intercultural competence
On the Refractive Index of Ageing Dispersions of Laponite
Aqueous dispersion of Laponite at low ionic concentration is of interest
since it undergoes structural evolution with respect to time, which is usually
termed as ageing. In this work we study the refractive index behavior as a
function of ageing time, concentration and temperature. We observed that the
extended Lorenz-Lorentz equation fitted the refractive index dependence on
concentration and temperature very well. The refractive index did not show any
dependence on ageing time. However, the dependence of refractive index on
concentration showed a marked change as the system underwent transition from an
isotropic to a biphasic state. The slope of the refractive index-density data
is remarkably close to that of water at all Laponite concentrations. In the
context of transport phenomena, optical measurements such as interferometry can
exploit the water-like behavior of Laponite dispersions.Comment: 13 pages, 3 figures, to appear in Applied Clay Scienc
Value of cyclin A immunohistochemistry for cancer risk stratification in Barrett esophagus surveillance A multicenter case-control study
The value of endoscopic Barrett esophagus (BE) surveillance based on histological diagnosis of low-grade dysplasia (LGD) remains
debated given the lack of adequate risk stratification. The aim of this study was to evaluate the predictive value of cyclin A expression
and to combine these results with our previously reported immunohistochemical p53, AMACR, and SOX2 data, to identify a panel of
biomarkers predicting neoplastic progression in BE.
We conducted a caseâcontrol study within a prospective cohort of 720 BE patients. BE patients who progressed to high-grade
dysplasia (HGD, n=37) or esophageal adenocarcinoma (EAC, n=13), defined as neoplastic progression, were classified as cases
and patients without neoplastic progression were classified as controls (n=575). Cyclin A expression was determined by
immunohistochemistry in all 625 patients; these results were combined with the histological diagnosis and our previous p53,
AMACR, and SOX2 data in loglinear regression models. Differences in discriminatory ability were quantified as changes in area under
the ROC curve (AUC) for predicting neoplastic progression.
Cyclin A surface positivity significantly increased throughout the metaplasiaâdysplasiaâcarcinoma sequences and was seen in 10%
(107/1050) of biopsy series without dysplasia, 33% (109/335) in LGD, and 69% (34/50) in HGD/EAC. Positive cyclin A expression was
associated with an increased risk of neoplastic progression (adjusted relative risk (RRa) 2.4; 95% CI: 1.7â3.4). Increases in AUC were
substantial for P53 (+0.05), smaller for SOX2 (+0.014), minor for cyclin A (+0.003), and none for AMARC (0.00).
Cyclin A immunopositivity was associated with an increased progression risk in BE patients. However, compared to p53 and SOX2,
the incremental value of cyclin A was limited. The use of biomarkers has the potential to significantly improve risk stratification in BE
Irreversible Aging Dynamics and Generic Phase Behavior of Aqueous Suspensions of Laponite
In this work we study the aging behavior of aqueous suspension of Laponite
having 2.8 weight % concentration using rheological tools. At various salt
concentration all the samples demonstrate orientational order when observed
using crossed polarizers. In rheological experiments we observe inherent
irreversibility in the aging dynamics which forces the system not to rejuvenate
to the same state in the shear melting experiment carried out at a later date
since preparation. The extensive rheological experiments carried out as a
function of time elapsed since preparation demonstrate the self similar trend
in the aging behavior irrespective of the concentration of salt. We observe
that the exploration of the low energy states as a function of aging time is
only kinetically affected by the presence of salt. We estimate that the energy
barrier to attain the low energy states decreases linearly with increase in the
concentration of salt. The observed superposition of all the elapsed time and
the salt concentration dependent data suggests that the aging that occurs in
low salt concentration systems over a very long period is qualitatively similar
to the aging behavior observed in systems with high salt concentration over a
shorter period.Comment: 27 pages, 8 figures. Langmuir, in pres
Nowhere to go: How stigma limits the options of female drug users after release from jail
<p>Abstract</p> <p>Background</p> <p>Drug and alcohol using women leaving prison or jail face many challenges to successful re-integration in the community and are severely hampered in their efforts by the stigma of drug or alcohol use compounded by the stigma of incarceration.</p> <p>Methods</p> <p>This qualitative study is based on individual semi-structured interviews and focus groups with 17 women who had recently left jail about the challenges they faced on reentry.</p> <p>Results</p> <p>Our analysis identified three major themes, which are related by the overarching influence of stigma: survival (jobs and housing), access to treatment services, and family and community reintegration.</p> <p>Conclusion</p> <p>Stigma based on drug use and incarceration works to increase the needs of women for health and social services and at the same time, restricts their access to these services. These specific forms of stigma may amplify gender and race-based stigma. Punitive drug and social policies related to employment, housing, education, welfare, and mental health and substance abuse treatment make it extremely difficult for women to succeed.</p
Lime Cake as an Alternative Stabiliser for Loose Clayey Loams
Lime Cake (precipitated calcium carbonate PCC), a by-product of sugar production, is proposed as a stabiliser for improvement of loose silty clayey loams. Two inorganic pedogenic and organic precipitated calcium carbonate polymorphs are artificially synthesized into a base loosely compacted loamy soil. Formation, micromorphology, quality of cementing bonds, and physiochemical interactions in the interlayer are modelled at molecular level and verified by a suite of micro-analytical spectrometry techniques. Emphasis is put into determining the impacts of polysaccharides on soil strength and implications on soil pore anatomy. Erodibility, compressibility, volumetric change, and hydro-mechanical behaviour of base, and modified soils at yield and post-yield states are studied. Anomalies in suction-controlled post-yield stressâstrain behaviour of modified soils are discussed and explained within the tenets of mechanics of composite soils with double porosity. PCC-reinforcement offers the closest possible packing at optimum water content. Desiccation cracking remains likely, but at relatively higher lower-bound water contents. Under low confinement levels and unsaturated state, strain-hardening prevails. Loss of shear strength on saturation is minimal. When saturated, PCC-reinforced soil develops substantially high levels of shear strength at all strain levels. Higher levels of confinement are needed for organic fibrous and onion-skin coating matters to effectively encrust the soil pore network; such high levels, however, leads to formation of an unwelcomed brittle, strainâsoftening stressâstress behaviour
Clay micromechanics : an analysis of elementary mechanisms of clay particle interactions to gain insight into compression behaviour of clay
The macroscopic response of geomaterials is controlled by the processes occurring at the microscale. Understanding these processes is key to interpret experimental data, understand fundamental modes of stress-strain behaviour, inform âcontinuumâ macroscopic constitutive models, and develop quantitative predictive tools based on Discrete Element Method (DEM) approaches. Unlike granular materials, mechanisms at the particle scale controlling macro-mechanical behaviour of clays are still largely ignored. This paper presents an analysis of elementary mechanisms of clay particle interactions with the aim of gaining an insight into behaviour of clay and advance the process of defining suitable contact laws to be implemented into DEM formulations
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