Intrinsic Environmental Vulnerability as Shallow Landslide Susceptibility in Environmental Impact Assessment

This work investigated the susceptibility factors that trigger shallow landslides. In particular, the objective of the research was the implementation of a method to determine the relevant factors that can trigger shallow landslide events. However, with respect to the existing methods, the integration with historical datasets and the inclusion of spatial factors displaying dynamics in the same characteristic timescales were specific features of the developed tool. The study area included the watersheds of the Sessera and Strona rivers in the alpine area of the Province of Biella (Piedmont, NW Italy). The method was developed and tested from two sub-datasets derived from an integrated dataset that referred to an intense event, involving the same area, that occurred in 1968 (2\u20133 November). This allowed the implementation of an integrated representation of landslides\u2019 predisposing factors and the identification and classification in dierent groups of the areas susceptible to geo-hydrological instability processes. The previously existing databases were verified and integrated into a geographic information system (GIS) environment, giving a potentially sharable source of information for planning purposes. The obtained maps represent a metric of one of the possible intrinsic environmental vulnerability factors for the area under study. Consequently, this method can represent a future instrument for determining the intrinsic environmental vulnerability dependent on landslides within an environmental impact assessment (EIA), as required by the most recent European regulation on EIA. Moreover, the shared information can be used to implement informed policy and planning processes, based on a bottom-up approach. In particular, the availability online of landslide susceptibility maps could support the generation of augmented information\u2014useful for both local administrators and planners as well as for stakeholders willing to implement specific projects or infrastructure in vulnerable areas, such as mountain

Nutritional and Plasma Antioxidant Status Assessment in a Group of Old Alzheimer\u2019s Inpatients

This study was carried out to assess the nutritional and plasma antioxidant status of Alzheimer\u2019s inpatients compared to age-matched controls by means of anthropometric measurements, neuropsychological and nutritional tests and plasma biomarkers. Assessment of nutritional biomarkers of prooxidant/antioxidant balance in patients with AD as well as nutritional status and neuropsychological evaluation are important since many studies have demonstrated their association with cognitive impairment. This cross sectional study was carried out in 35 subjects recruited in a geriatric institution in Pavia, Northern Italy. Cases mean Body Mass Index (BMI) was lower than controls\u2019 one as well as mid arm circumference, triceps skinfold and arm muscle circumference. Both inpatients MNA and MMSE mean scores were lower than controls ones. Plasma levels of lutein plus zeaxanthin, beta-cryptoxanthin, lycopene, alfa tocopherol, ascorbic acid were significantly lower (p < 0.05) in AD in patients as well as superoxide desmutase and glutathione peroxidase concentrations, while all the other biochemical markers levels did not differ. Plasma antioxidant levels and activities were decreased in AD and could be biologically predictive of an early mild cognitive decline, suggesting early intervention on dietary antioxidant intake

Time–frequency representation of autoionization dynamics in helium

Autoionization, which results from the interference between direct photoionization and photoexcitation to a discrete state decaying to the continuum by configuration interaction, is a well known example of the important role of electron correlation in light–matter interaction. Information on this process can be obtained by studying the spectral, or equivalently, temporal complex amplitude of the ionized electron wave packet. Using an energy-resolved interferometric technique, we measure the spectral amplitude and phase of autoionized wave packets emitted via the sp2+ and sp3+ resonances in helium. These measurements allow us to reconstruct the corresponding temporal profiles by Fourier transform. In addition, applying various time–frequency representations, we observe the build-up of the wave packets in the continuum, monitor the instantaneous frequencies emitted at any time and disentangle the dynamics of the direct and resonant ionization channels

Rupture of splenic artery aneurysm: minimally invasive management

Los aneurismas de la circulación esplácnica son una entidad poco frecuente, pero potencialmente mortal, con una prevalencia que alcanza hasta el 10% en autopsias. El aneurisma de la arteria esplénica (AAE) representa hasta el 60% de todos los aneurismas de la circulación esplácnica y es el tercer aneurisma intraabdominal más frecuente después del de la aorta y las arterias ilíacas. Fue descripto por primera vez en cadáveres en 1770 por Beaussier y el primer diagnóstico preoperatorio lo hizo Hoegler, en 1920. Presentamos una paciente mujer de 61 años que consulta en el servicio de guardia por dolor epigástrico de 2 días de evolución, de comienzo brusco con irradiación al dorso.Facultad de Ciencias Médica

Intestinal intussusception in adults: report of two cases

La intususcepción intestinal, también llamada invaginación intestinal, es una patología de presentación poco frecuente en el adulto, con sintomatología que varía entre formas agudas y crónicas, lo que lleva comúnmente a desorientar al médico tratante, sobre todo cuando es de presentación aguda, y realizar el diagnóstico definitivo durante el intraoperatorio. En el siguiente trabajo se describen 2 casos clínicos, con su forma de presentación (aguda y crónica), la metodología de estudio y la resolución quirúrgica realizada, acompañado de una breve revisión bibliográfica.Intestinal intussusception or Intestinal Invagination is a rare presentation pathology in the adult, with symptomatology varying between acute and chronic forms, which commonly leads to disorienting the treating physician, especially when it is acutely presenting, leading to definitive diagnosis during the intraoperative period. The following paper describes 2 clinical cases, with their presentation (acute and chronic), the study methodology and the surgical resolution performed, accompanied by a brief bibliographic review.Facultad de Ciencias Médica

The relation between amyotrophic lateral sclerosis and inorganic selenium in drinking water: a population-based case-control study

<p>Abstract</p> <p>Background</p> <p>A community in northern Italy was previously reported to have an excess incidence of amyotrophic lateral sclerosis among residents exposed to high levels of inorganic selenium in their drinking water.</p> <p>Methods</p> <p>To assess the extent to which such association persisted in the decade following its initial observation, we conducted a population-based case-control study encompassing forty-one newly-diagnosed cases of amyotrophic lateral sclerosis and eighty-two age- and sex-matched controls. We measured long-term intake of inorganic selenium along with other potentially neurotoxic trace elements.</p> <p>Results</p> <p>We found that consumption of drinking water containing ≥ 1 μg/l of inorganic selenium was associated with a relative risk for amyotrophic lateral sclerosis of 5.4 (95% confidence interval 1.1-26) after adjustment for confounding factors. Greater amounts of cumulative inorganic selenium intake were associated with progressively increasing effects, with a relative risk of 2.1 (95% confidence interval 0.5-9.1) for intermediate levels of cumulative intake and 6.4 (95% confidence interval 1.3-31) for high intake.</p> <p>Conclusion</p> <p>Based on these results, coupled with other epidemiologic data and with findings from animal studies that show specific toxicity of the trace element on motor neurons, we hypothesize that dietary intake of inorganic selenium through drinking water increases the risk for amyotrophic lateral sclerosis.</p

Processing Ordinality and Quantity: The Case of Developmental Dyscalculia

In contrast to quantity processing, up to date, the nature of ordinality has received little attention from researchers despite the fact that both quantity and ordinality are embodied in numerical information. Here we ask if there are two separate core systems that lie at the foundations of numerical cognition: (1) the traditionally and well accepted numerical magnitude system but also (2) core system for representing ordinal information. We report two novel experiments of ordinal processing that explored the relation between ordinal and numerical information processing in typically developing adults and adults with developmental dyscalculia (DD). Participants made “ordered” or “non-ordered” judgments about 3 groups of dots (non-symbolic numerical stimuli; in Experiment 1) and 3 numbers (symbolic task: Experiment 2). In contrast to previous findings and arguments about quantity deficit in DD participants, when quantity and ordinality are dissociated (as in the current tasks), DD participants exhibited a normal ratio effect in the non-symbolic ordinal task. They did not show, however, the ordinality effect. Ordinality effect in DD appeared only when area and density were randomized, but only in the descending direction. In the symbolic task, the ordinality effect was modulated by ratio and direction in both groups. These findings suggest that there might be two separate cognitive representations of ordinal and quantity information and that linguistic knowledge may facilitate estimation of ordinal information

The discovery BPD (D-BPD) program: Study protocol of a prospective translational multicenter collaborative study to investigate determinants of chronic lung disease in very low birth weight infants

Background: Premature birth is a growing and serious public health problem affecting more than one of every ten infants worldwide. Bronchopulmonary dysplasia (BPD) is the most common neonatal morbidity associated with prematurity and infants with BPD suffer from increased incidence of respiratory infections, asthma, other forms of chronic lung illness, and death (Day and Ryan, Pediatr Res 81: 210-213, 2017; Isayama et la., JAMA Pediatr 171:271-279, 2017). BPD is now understood as a longitudinal disease process influenced by the intrauterine environment during gestation and modulated by gene-environment interactions throughout the neonatal and early childhood periods. Despite of this concept, there remains a paucity of multidisciplinary team-based approaches dedicated to the comprehensive study of this complex disease. Methods: The Discovery BPD (D-BPD) Program involves a cohort of infants < 1,250 g at birth prospectively followed until 6 years of age. The program integrates analysis of detailed clinical data by machine learning, genetic susceptibility and molecular translation studies. Discussion: The current gap in understanding BPD as a complex multi-trait spectrum of different disease endotypes will be addressed by a bedside-to-bench and bench-to-bedside approach in the D-BPD program. The D-BPD will provide enhanced understanding of mechanisms, evolution and consequences of lung diseases in preterm infants. The D-BPD program represents a unique opportunity to combine the expertise of biologists, neonatologists, pulmonologists, geneticists and biostatisticians to examine the disease process from multiple perspectives with a singular goal of improving outcomes of premature infants. Trial registration: Does not apply for this study.Fil: Ofman, Gaston. University of Alabama at Birmingahm; Estados UnidosFil: Caballero, Mauricio Tomás. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Álvarez Paggi, Damián Jorge. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Marzec, Jacqui. National Institute of Environmental Health Sciences; Estados UnidosFil: Nowogrodzki, Florencia. No especifíca;Fil: Cho, Hye Youn. National Institute of Environmental Health Sciences; Estados UnidosFil: Sorgetti, Mariana. No especifíca;Fil: Colantonio, Guillermo. No especifíca;Fil: Bianchi, Alejandra. No especifíca;Fil: Prudent, Luis M.. Fundación para la Salud Materno Infantil; ArgentinaFil: Vain, Néstor Eduardo. Fundación para la Salud Materno Infantil; Argentina. Sanatorio de la Trinidad Palermo.; ArgentinaFil: Mariani, Gonzalo Luis. Hospital Italiano; ArgentinaFil: Digregorio, Jorge. Sanatorio de la Trinidad Palermo.; ArgentinaFil: Lopez Turconi, Elba. No especifíca;Fil: Osio, Cristina. Sanatorio "Otamendi y Miroli S. A."; ArgentinaFil: Galletti, Maria Fernanda. Hospital Italiano; ArgentinaFil: Quiros, Mariangeles. Clinica y Maternidad Suizo Argentina; ArgentinaFil: Brum, Andrea. Sanatorio de la Trinidad Palermo.; ArgentinaFil: Lopez Garcia, Santiago. No especifíca;Fil: Garcia, Silvia. Sanatorio "Otamendi y Miroli S. A."; ArgentinaFil: Bell, Douglas. National Institute of Environmental Health Sciences; Estados UnidosFil: Jones, Marcus H.. Pontificia Universidade Católica do Rio Grande do Sul; BrasilFil: Tipple, Trent E.. University of Alabama at Birmingahm; Estados UnidosFil: Kleeberger, Steven R.. National Institute of Environmental Health Sciences; Estados UnidosFil: Polack, Fernando Pedro. University of Alabama at Birmingahm; Estados Unido