Correlated noise in networks of gravitational-wave detectors: subtraction and mitigation

One of the key science goals of advanced gravitational-wave detectors is to observe a stochastic gravitational-wave background. However, recent work demonstrates that correlated magnetic fields from Schumann resonances can produce correlated strain noise over global distances, potentially limiting the sensitivity of stochastic background searches with advanced detectors. In this paper, we estimate the correlated noise budget for the worldwide Advanced LIGO network and conclude that correlated noise may affect upcoming measurements. We investigate the possibility of a Wiener filtering scheme to subtract correlated noise from Advanced LIGO searches, and estimate the required specifications. We also consider the possibility that residual correlated noise remains following subtraction, and we devise an optimal strategy for measuring astronomical parameters in the presence of correlated noise. Using this new formalism, we estimate the loss of sensitivity for a broadband, isotropic stochastic background search using 1 yr of LIGO data at design sensitivity. Given our current noise budget, the uncertainty with which LIGO can estimate energy density will likely increase by a factor of ~4--if it is impossible to achieve significant subtraction. Additionally, narrowband cross-correlation searches may be severely affected at low frequencies f < 45 Hz without effective subtraction.Comment: 16 pages, 8 figure

Correlated magnetic noise in global networks of gravitational-wave detectors: Observations and implications

One of the most ambitious goals of gravitational-wave astronomy is to observe the stochastic gravitational-wave background. Correlated noise in two or more detectors can introduce a systematic error, which limits the sensitivity of stochastic searches. We report on measurements of correlated magnetic noise from Schumann resonances at the widely separated LIGO and Virgo detectors. We investigate the effect of this noise on a global network of gravitational-wave detectors and derive a constraint on the allowable coupling of environmental magnetic fields to test mass motion in gravitational-wave detectors. We find that while correlated noise from global electromagnetic fields could be safely ignored for initial LIGO stochastic searches, it could severely impact Advanced LIGO, Advanced Virgo, KAGRA, as well as third-generation detectors

DHA Improves Cognition and Prevents Dysfunction of Entorhinal Cortex Neurons in 3xTg-AD Mice

Defects in neuronal activity of the entorhinal cortex (EC) are suspected to underlie the symptoms of Alzheimer's disease (AD). Whereas neuroprotective effects of docosahexaenoic acid (DHA) have been described, the effects of DHA on the physiology of EC neurons remain unexplored in animal models of AD. Here, we show that DHA consumption improved object recognition (↑12%), preventing deficits observed in old 3xTg-AD mice (↓12%). Moreover, 3xTg-AD mice displayed seizure-like akinetic episodes, not detected in NonTg littermates and partly prevented by DHA (↓50%). Patch-clamp recording revealed that 3xTg-AD EC neurons displayed (i) loss of cell capacitance (CC), suggesting reduced membrane surface area; (ii) increase of firing rate versus injected current (F-I) curve associated with modified action potentials, and (iii) overactivation of glutamatergic synapses, without changes in synaptophysin levels. DHA consumption increased CC (↑12%) and decreased F-I slopes (↓21%), thereby preventing the opposite alterations observed in 3xTg-AD mice. Our results indicate that cognitive performance and basic physiology of EC neurons depend on DHA intake in a mouse model of AD