A Resource-Based View Of International Human Resources: Toward A Framework of Integrative and Creative Capabilities

Drawing on organizational learning and MNC perspectives, we extend the resource-based view to address how international human resource management provides sustainable competitive advantage. We develop a framework that emphasizes and extends traditional assumptions of the resource-based view by identifying the learning capabilities necessary for a complex and changing global environment. These capabilities address how MNCs might both create new HR practices in response to local environments and integrate existing HR practices from other parts of the firm (affiliates, regional headquarters, and global headquarters). In an effort to understand the nature of such capabilities, we discuss aspects of human capital, social capital, and organizational capital that might be linked to their development. Page

Giving Due Process Its Due: Why Deliberate Indifference Should Be Confined to Claims Arising Under the Cruel and Unusual Punishment Clause

This Note discusses culpability requirements for claims brought by pretrial detainees and convicted prisoners. The initial focus is on deliberate indifference, a culpability requirement formulated under the Cruel and Unusual Punishment Clause but symmetrically applied to claims arising under the Due Process Clause of the Fourteenth Amendment. The Note then shifts to Kingsley v. Hendrickson, a landmark Supreme Court decision that casts doubt on the application of Eighth-Amendment standards to Fourteenth-Amendment claims. Finally, this Note advocates for the application of objective unreasonableness, a different culpability requirement, to claims arising under the Due Process Clause. It does so on the basis that due process is a dynamic concept, independent of the Eighth Amendment’s demands

Crystal structure of 3-{(E)-[(3, 4-dichloro-phenyl)imino]methyl}benzene-1, 2-diol

The authors acknowledge the provision of funds for the purchase of diffractometer and encouragement by Dr.Muhammad Akram Chaudhary, Vice Chancellor, University of Sargodha, Pakistan.Peer reviewedPublisher PD

Patch Clamp Study of Serotonin-Gated Currents via 5-HT Type 3 Receptors by Using a Novel Approach SHAM for Receptor Channel Scanning

We studied 5-hydroxy tryptamine type 3 (5-HT(3)) receptors transfected in tsA-201 cell line to examine serotonin-induced whole cell currents. Using the site-directed mutagenesis technique, we individually mutated each residue in the membrane-spanning M2 segment to histidine. A high proportion of tsA-201 cells cotransfected with the cDNAs of 5-HT(3)R and CD8 produced large amplitude responses (0.5−7.0 nA) to serotonin. The dose-response curve of wild-type (WT) receptor ranging from 0.5 to 500 μmole increases its K(d) values, and V(max) of 5-HT(3)R falls at low external pH as if protonation of an acid group is enough to block the channel. Lysine at position 281, a basic residue, is more susceptible to acidification-induced blockade of the 5-HT(3)R channel. Dose-response curves of K281S (replacing lysine at the 281 position with serine) at different pH are not significantly modulated, and histidine substitutions at the three consecutive positions 293, 294, and 296 eliminate the pH block of the channel

Catastrophic Effects of Floods on Environment and Health: Evidence from Pakistan

Torrential rains and floods have been causing irreplaceable losses to both human lives and environment in Pakistan. This loss has reached to an extent of assively aggrieved situation to reinstate life at operationally viable position. This paper unfolds the notion that only constructive paradigm shift to overcome this phenomenon is vital as a strategy. Multiple levels of observations and on-site assessment of various calamity-prone venues were considered to probe into this scenario. Some of the grave site in Sindh and Punjab were observed and necessarily practicable measures were recommended to avoid loss to human health and environment. The paper finds that a consistent drastic management authority on national level with appropriate caliber and forecasting expertise can reduce the damage to human life and environment to great extent. Weather forecasting system need to be installed at many appropriately observed cities and towns in the country with adequate man power, funds and technical recourses. By implementing the proper frame work of prevention and mitigation of floods country can save the major costs cleanup and recovery. These measures are expected to reduce operational cost of state in terms of GDP and GNP to restore life and environment

Molecular and morphological characterization of the tapeworm Taenia hydatigena (Pallas, 1766) in sheep from Iran

Although Taenia hydatigena is one of the most prevalent taeniid species of livestock, very little molecular genetic information exists for this parasite. Up to 100 sheep isolates of T. hydatigena were collected from 19 abattoirs located in the provinces of Tehran, Alborz and Kerman. A calibrated microscope was used to measure the larval rostellar hook lengths. Following DNA extraction, fragments of cytochrome c oxidase 1 (CO1) and 12S rRNA genes were amplified by the polymerase chain reaction method and the amplicons were subjected to sequencing. The mean total length of large and small hooks was 203.4 μm and 135.9 μm, respectively. Forty CO1 and 39 12S rRNA sequence haplotypes were obtained in the study. The levels of pairwise nucleotide variation between individual haplotypes of CO1 and 12S rRNA genes were determined to be between 0.3-3.4% and 0.2-2.1%, respectively. The overall nucleotide variation among all the CO1 haplotypes was 9.7%, and for all the 12S rRNA haplotypes it was 10.1%. A significant difference was observed between rostellar hook morphometry and both CO1 and 12S rRNA sequence variability. A significantly high level of genetic variation was observed in the present study. The results showed that the 12S rRNA gene is more variable than CO1. © 2013 Cambridge University Press

Heart Rate Variability Time Analyses of the Streptozotocin- Diabetic Rat

As the world prevalence of diabetes mellitus (DM) increases, animal models of the disease's progression are required for researching effective treatment. The streptozotocin (STZ) treated rat is known to cause hyperglycaemia. This study confirms that this animal model also displays DM physiological effects in the animal heart rate (HR) and heart rate variability (HRV). In particular, 5 minutes of rat (n=13) electrocardiogram (ECG) is acquired hourly for 30 days. At day 10, the animal (n=7) is dosed with STZ and the ECG is analyzed in order to determine the HR and HRV. The HRV is indexed using two time-based analyses, based on long-term (24hr) and short-term (5min) analyses. All analyses are compared to control non-STZ dosed animals (n=6) and display significant DM effects

2-[(E)-3,4-Dimeth­oxy­benzyl­idene]hydrazinecarboxamide

In the title compound, C10H13N3O3, the 3,4-dimeth­oxy­benzyl­idene and hydrazinecarboxamide groups are oriented at a dihedral angle of 53.82 (6)° and an intra­molecular N—H⋯N hydrogen bond generates an S(5) ring motif. In the crystal, mol­ecules are linked by N—H⋯O hydrogen bonds into sheets propagating in (-201), which feature R 1 2(5), R 2 2(8) and R 2 4(14) loops

Desempeño a largo plazo de secciones de pavimentos existentes de concreto asfáltico

RESUMEN: Los pavimentos de carreteras están diseñados para soportar las cargas proyectadas del tr·Æ co y a la vez proporcionar alta calidad para los niveles de servicio. Las grandes cargas que los pavimentos experimentan durante su existencia en conjunto con las condiciones variables de clima y humedad aceleran el proceso de deterioro y podrían causar fallas prematuras a los pavimentos. En esta investigación se realiza un estudio de patología para evaluar el desempeño actual de varios concretos asfálticos. La condición estructural de secciones de concreto asfáltico, localizados en el Estado de Ohio, Estados Unidos, se realizan por medio del método de ensayo del DeØ ectómetro de Impacto (FWD). La interpretación de los ensayos con FWD permite la evaluación de potenciales rehabilitaciones a corto y mediano plazo. La metodología de análisis e interpretación de resultados presentados en este artículo para el caso de los 110 km de pavimento de concreto asfáltico en el Estado de Ohio, se muestra como una técnica valiosa en el caso colombiano para determinar, con mediciones reales de campo, la condición y potencial rehabilitación del sistema de infraestructura que se requiere para garantizar el desarrollo económico sostenible del país.ABSTRACT: Highway pavements are designed to withstand the projected trafÆ c loads while providing a high quality level of service. The large loads that pavements experience during the design life in conjunction with variable climate and moisture conditions accelerate the deterioration process and might cause premature failure of the pavements. In this research, a forensic study to assess the current performance of several asphalt concrete (AC) pavements is conducted. The structural condition of the AC sections, located in the State of Ohio, United States, was determined by means of the Falling Weight DeØ ectometer (FWD) testing method. The evaluation and interpretation of the FWD tests permit the assessment of potential short or medium-term rehabilitation projects. The methodology of analysis and data interpretation presented in this paper for the case of 110 km of asphalt concrete pavement in the State of Ohio, stands as a valuable technique in Colombia to determine, with actual Æ eld measurements, the condition and potential rehabilitation of the infrastructure system that is required to guarantee the sustainable economic development of the country