Management of hypertensive crisis: British and Irish Hypertension Society position document

Patients with hypertensive emergencies, malignant hypertension and acute severe hypertension are managed heterogeneously in clinical practice. Initiating anti-hypertensive therapy and setting BP goal in acute settings requires important considerations which differ slightly across various diagnoses and clinical contexts. This position paper by British and Irish Hypertension Society, aims to provide clinicians a framework for diagnosing, evaluating, and managing patients with hypertensive crisis, based on the critical appraisal of available evidence and expert opinion

Significance-Driven Logic Compression for Energy Efficient Multiplier Design

Approximate Arithmetic is a new design paradigm that is being used in many applications which are tolerant to imprecision and do not require accurate results. It can reduce circuit complexity, delay and energy consumption by relaxing accuracy requirements. The partial product bit matrix can be reduced based on their progressive bit significance using a Significance Driven Logic Compression(SDLC) approach. Further, the complexity of the approximate multiplier can be reduced by using Approximate adders in place of exact adders in the accumulation method. Removing some of the transistors from an accurate adder will result in an approximate adder. By using approximate adders which have less number of transistors, the power, propagation delay, and the switching capacitance can be reduced. In this paper, approximate multipliers are implemented using different approximate adders and they are compared with an exact multiplier in terms of power, delay and energy savings

Lesions of sellar and parasellar region: a pathologists view

Introduction: Sellar and parasellar region is an anatomically intricate area. The lesions include a wide variety of conditions ranging from pituitary adenoma to empty sella syndrome, apoplexy, congenital or acquired conditions, craniopharyngioma and meningioma. Most common of them all is pituitary adenoma. Aims and objectives:To study the various lesions of sellar and parasellar regions including variants of pituitary adenoma and meningiomaand to compare their squash cytology with histopathology diagnosis. Material and methods:Over a period of 3 years all the lesions of sellar and suprasellar region detected clinically and radiologically were studied. Results: The most common lesion was pituitary adenoma (50%) followed by meningioma (28.6%) and craniopharyngioma (21.4%). Among pituitary adenoma the commonest type was somatotroph type. Conclusion: Both neoplastic and non-neoplastic lesions occur in the sellar and parasellar region. Clinical and pathological correlation will lead to a specific and accurate diagnosis of the seller and parasellar lesions. Squash cytology findings, if interpreted with clinical picture and radio-imaging findings, will help to reach an accurate and rapid diagnosis of rare intracranial tumors