8 research outputs found

    Diastereoselective reduction of α-keto esters derived from functionalised cholic acid

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    The reduction of phenylglyoxalate 2a and pyruvate 2b with LiBH4 in THF at -80 degrees C yield the corresponding alpha-hydroxy esters with ca. 70% diastereoselectivity

    Bile-Acids in Asymmetric-Synthesis.2. Cholic-Acid Derived Novel Chiral Auxiliaries For Asymmetric Diels-Alder Reactions

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    Cholic acid-based chiral acrylate 5 yields a Diels-Alder adduct with cyclopen

    Sulfamic Acid and Its N- and O-Substituted Derivatives

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