Using generalized PowerFlux methods to estimate the parameters of periodic gravitational waves

We investigate methods to estimate the parameters of the gravitational-wave signal from a spinning neutron star using Fourier transformed segments of the strain response from an interferometric detector. Estimating the parameters from the power, we find generalizations of the PowerFlux method. Using simulated elliptically polarized signals injected into Gaussian noise, we apply the generalized methods to estimate the squared amplitudes of the plus and cross polarizations (and, in the most general case, the polarization angle), and test the relative detection efficiencies of the various methods.Comment: 8 pages, presented at Amalid7, Sydney, Australia (July 2007), fixed minor typos and clarified discussion to match published CQG version; updated reference

The r-modes in accreting neutron stars with magneto-viscous boundary layers

We explore the dynamics of the r-modes in accreting neutron stars in two ways. First, we explore how dissipation in the magneto-viscous boundary layer (MVBL) at the crust-core interface governs the damping of r-mode perturbations in the fluid interior. Two models are considered: one assuming an ordinary-fluid interior, the other taking the core to consist of superfluid neutrons, type II superconducting protons, and normal electrons. We show, within our approximations, that no solution to the magnetohydrodynamic equations exists in the superfluid model when both the neutron and proton vortices are pinned. However, if just one species of vortex is pinned, we can find solutions. When the neutron vortices are pinned and the proton vortices are unpinned there is much more dissipation than in the ordinary-fluid model, unless the pinning is weak. When the proton vortices are pinned and the neutron vortices are unpinned the dissipation is comparable or slightly less than that for the ordinary-fluid model, even when the pinning is strong. We also find in the superfluid model that relatively weak radial magnetic fields ~ 10^9 G (10^8 K / T)^2 greatly affect the MVBL, though the effects of mutual friction tend to counteract the magnetic effects. Second, we evolve our two models in time, accounting for accretion, and explore how the magnetic field strength, the r-mode saturation amplitude, and the accretion rate affect the cyclic evolution of these stars. If the r-modes control the spin cycles of accreting neutron stars we find that magnetic fields can affect the clustering of the spin frequencies of low mass x-ray binaries (LMXBs) and the fraction of these that are currently emitting gravitational waves.Comment: 19 pages, 8 eps figures, RevTeX; corrected minor typos and added a referenc

Role of chondroitin sulfate proteoglycans (CSPGs) in synaptic plasticity and neurotransmission in mammalian spinal cord.

Chronic unilateral hemisection (HX) of the adult rat spinal cord diminishes conduction through intact fibers in the ventrolateral funiculus (VLF) contralateral to HX. Intraspinal injections of Chondroitinase-ABC, known to digest chondroitin sulfate proteoglycans (CSPGs) in the vicinity of injury, prevented this decline of axonal conduction. This was associated with improved locomotor function. We further injected three purified CSPGs into the lateral column of the uninjured cord at T10: NG2 and neurocan, which increase in the vicinity of a spinal injury, and aggrecan, which decreases. Intraspinal injection of NG2 acutely depressed axonal conduction through the injection region in a dose dependent manner. Similar injections of saline, aggrecan, or neurocan had no significant effect. These results identify a novel acute action of CSPGs on axonal conduction in spinal cord, and suggest that antagonism of proteoglycans reverses or prevents the decline of axonal conduction, in addition to stimulating axonal growth

Covariant Vortex In Superconducting-Superfluid-Normal Fluid Mixtures with Stiff Equation of State

The integrals of motion for a cylindrically symmetric stationary vortex are obtained in a covariant description of a mixture of interacting superconductors, superfluids and normal fluids. The relevant integrated stress-energy coefficients for the vortex with respect to a vortex-free reference state are calculated in the approximation of a ``stiff'', i.e. least compressible, relativistic equation of state for the fluid mixture. As an illustration of the foregoing general results, we discuss their application to some of the well known examples of ``real'' superfluid and superconducting systems that are contained as special cases. These include Landau's two-fluid model, uncharged binary superfluid mixtures, rotating conventional superconductors and the superfluid neutron-proton-electron plasma in the outer core of neutron stars.Comment: 14 pages, uses RevTeX and amssymb, submitte

R-Modes in Superfluid Neutron Stars

The analogs of r-modes in superfluid neutron stars are studied here. These modes, which are governed primarily by the Coriolis force, are identical to their ordinary-fluid counterparts at the lowest order in the small angular-velocity expansion used here. The equations that determine the next order terms are derived and solved numerically for fairly realistic superfluid neutron-star models. The damping of these modes by superfluid ``mutual friction'' (which vanishes at the lowest order in this expansion) is found to have a characteristic time-scale of about 10^4 s for the m=2 r-mode in a ``typical'' superfluid neutron-star model. This time-scale is far too long to allow mutual friction to suppress the recently discovered gravitational radiation driven instability in the r-modes. However, the strength of the mutual friction damping depends very sensitively on the details of the neutron-star core superfluid. A small fraction of the presently acceptable range of superfluid models have characteristic mutual friction damping times that are short enough (i.e. shorter than about 5 s) to suppress the gravitational radiation driven instability completely.Comment: 15 pages, 8 figure

Thermogeologic mapping of the Moon from lunar orbit

The Infrared Scanning Radiometer (ISR) onboard the Apollo 17 Command-Service Module (CSM) mapped thermal emission of the lunar surface from orbit. Measured temperature values span the diurnal range of lunar temperatures (85 K to 400 K) and have an accuracy of approximately plus or minus 2 K. Surface spatial resolution at nadir is 2.2 km. This Apollo data is being revisited using data presentation software for the Macintosh computer, which was not available 20 years ago, even on mainframes. The new thermal images exhibit subtleties in the delineation of geophysical surface units that were unappreciated in the original survey of the data. Looking first at nighttime thermal emission from the ground tracks over Oceanus Procellarum to Mare Orientale, we have confirmed and expanded on earlier observations of regolith differences between mare and highlands and of a scheme for relative age-dating of larger impact craters of the Copernican age. We see an impact crater near Lenz, just north of Orientale, which exhibits an extraordinarily fresh ejecta blanket. Photography of this area is extremely poor, but we can see the feature in the Galileo data. We plan to derive geophysical surface properties of the overflown region using thermal models of regolith structures

Atmospheric neutrons

Contributions to fast neutron measurements in the atmosphere are outlined. The results of a calculation to determine the production, distribution and final disappearance of atmospheric neutrons over the entire spectrum are presented. An attempt is made to answer questions that relate to processes such as neutron escape from the atmosphere and C-14 production. In addition, since variations of secondary neutrons can be related to variations in the primary radiation, comment on the modulation of both radiation components is made

Edoxaban: an update on the new oral direct factor Xa inhibitor.

Edoxaban is a once-daily oral anticoagulant that rapidly and selectively inhibits factor Xa in a concentration-dependent manner. This review describes the extensive clinical development program of edoxaban, including phase III studies in patients with non-valvular atrial fibrillation (NVAF) and symptomatic venous thromboembolism (VTE). The ENGAGE AF-TIMI 48 study (N = 21,105; mean CHADS2 score 2.8) compared edoxaban 60 mg once daily (high-dose regimen) and edoxaban 30 mg once daily (low-dose regimen) with dose-adjusted warfarin [international normalized ratio (INR) 2.0-3.0] and found that both regimens were non-inferior to warfarin in the prevention of stroke and systemic embolism in patients with NVAF. Both edoxaban regimens also provided significant reductions in the risk of hemorrhagic stroke, cardiovascular mortality, major bleeding and intracranial bleeding. The Hokusai-VTE study (N = 8,292) in patients with symptomatic VTE had a flexible treatment duration of 3-12 months and found that following initial heparin, edoxaban 60 mg once daily was non-inferior to dose-adjusted warfarin (INR 2.0-3.0) for the prevention of recurrent VTE, and also had a significantly lower risk of bleeding events. Both studies randomized patients at moderate-to-high risk of thromboembolic events and were further designed to simulate routine clinical practice as much as possible, with edoxaban dose reduction (halving dose) at randomisation or during the study if required, a frequently monitored and well-controlled warfarin group, a well-monitored transition period at study end and a flexible treatment duration in Hokusai-VTE. Given the phase III results obtained, once-daily edoxaban may soon be a key addition to the range of antithrombotic treatment options

Improving LIGO calibration accuracy by tracking and compensating for slow temporal variations

Calibration of the second-generation LIGO interferometric gravitational-wave detectors employs a method that uses injected periodic modulations to track and compensate for slow temporal variations in the differential length response of the instruments. These detectors utilize feedback control loops to maintain resonance conditions by suppressing differential arm length variations. We describe how the sensing and actuation functions of these servo loops are parameterized and how the slow variations in these parameters are quantified using the injected modulations. We report the results of applying this method to the LIGO detectors and show that it significantly reduces systematic errors in their calibrated outputs.Comment: 13 pages, 8 figures. This is an author-created, un-copyedited version of an article published in Classical and Quantum Gravity. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from i

Indoor Environmental Exposures and Exacerbation of Asthma: An Update to the 2000 Review by the Institute of Medicine

Background: Previous research has found relationships between specific indoor environmental exposures and exacerbation of asthma. Objectives: In this review we provide an updated summary of knowledge from the scientific literature on indoor exposures and exacerbation of asthma. Methods: Peer-reviewed articles published from 2000 to 2013 on indoor exposures and exacerbation of asthma were identified through PubMed, from reference lists, and from authors’ files. Articles that focused on modifiable indoor exposures in relation to frequency or severity of exacerbation of asthma were selected for review. Research findings were reviewed and summarized with consideration of the strength of the evidence. Results: Sixty-nine eligible articles were included. Major changed conclusions include a causal relationship with exacerbation for indoor dampness or dampness-related agents (in children); associations with exacerbation for dampness or dampness-related agents (in adults), endotoxin, and environmental tobacco smoke (in preschool children); and limited or suggestive evidence for association with exacerbation for indoor culturable Penicillium or total fungi, nitrogen dioxide, rodents (nonoccupational), feather/down pillows (protective relative to synthetic bedding), and (regardless of specific sensitization) dust mite, cockroach, dog, and dampness-related agents. Discussion: This review, incorporating evidence reported since 2000, increases the strength of evidence linking many indoor factors to the exacerbation of asthma. Conclusions should be considered provisional until all available evidence is examined more thoroughly. Conclusion: Multiple indoor exposures, especially dampness-related agents, merit increased attention to prevent exacerbation of asthma, possibly even in nonsensitized individuals. Additional research to establish causality and evaluate interventions is needed for these and other indoor exposures. Citation: Kanchongkittiphon W, Mendell MJ, Gaffin JM, Wang G, Phipatanakul W. 2015. Indoor environmental exposures and exacerbation of asthma: an update to the 2000 review by the Institute of Medicine. Environ Health Perspect 123:6–20; http://dx.doi.org/10.1289/ehp.130792