236 research outputs found
Addressing Long-term Primary Care and Mental Health Concerns in Marginalized, Underdeveloped Communities
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Interaction between a cationic surfactant-like peptide and lipid vesicles and its relationship to antimicrobial activity
We investigate the properties of an antimicrobial
surfactant-like peptide (Ala)6(Arg), A6R, containing a
cationic headgroup. The interaction of this peptide with
zwitterionic (DPPC) lipid vesicles is investigated using a range of microscopic, X-ray scattering, spectroscopic, and calorimetric methods. The β-sheet structure adopted by A6R is disrupted in the presence of DPPC. A strong effect on the
small-angle X-ray scattering profile is observed: the Bragg
peaks from the DPPC bilayers in the vesicle walls are
eliminated in the presence of A6R and only bilayer form factor peaks are observed. All of these observations point to the interaction of A6R with DPPC bilayers. These studies provide insight into interactions between a model cationic peptide and vesicles, relevant to understanding the action of antimicrobial peptides on lipid membranes. Notably, peptide A6R exhibits antimicrobial activity without membrane lysis
Efeito dos perÃodos de envelhecimento na lixiviação de Ãons e de proteÃnas solúveis em sementes de milho
Pretreatment with H2O2 in maize seeds: effects on germination and seedling acclimation to salt stress
Influência do envelhecimento acelerado na anatomia da testa de sementes de soja, cv. Monsoy 8400
In vitro simulation of senescence-related membrane damage by ozone-induced lipid peroxidation
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