979 research outputs found
Extended conformal symmetry of the one-dimensional Bose gas
We show that the low-lying excitations of the one-dimensional Bose gas are described, at all orders in a 1/N expansion and at the first order in the inverse of the coupling constant, by an effective hamiltonian written in terms of an extended conformal algebra, namely the Cartan subalgebra of the algebra. This enables us to construct the first interaction term which corrects the hamiltonian of free fermions equivalent to a hard-core boson system
Custo de produção do gado puro sangue Charolês.
Foi estimado o custo da criação do rebanho Charolês, mantido para fim de pesquisa na UEPAE de São Carlos, com o objetivo de colher subsidios para o estudo da economicidade da pesquisa e de registrar incidências de custo aplicáveis a criação a nÃvel de empresa
A comparison of sensitivity-specificity imputation, direct imputation and fully Bayesian analysis to adjust for exposure misclassification when validation data are unavailable.
: Measurement error is an important source of bias in epidemiological studies. We illustrate three approaches to sensitivity analysis for the effect of measurement error: imputation of the 'true' exposure based on specifying the sensitivity and specificity of the measured exposure (SS); direct imputation (DI) using a regression model for the predictive values; and adjustment based on a fully Bayesian analysis. : We deliberately misclassify smoking status in data from a case-control study of lung cancer. We then implement the SS and DI methods using fixed-parameter (FBA) and probabilistic (PBA) bias analyses, and Bayesian analysis using the Markov-Chain Monte-Carlo program WinBUGS to show how well each recovers the original association. : The 'true' smoking-lung cancer odds ratio (OR), adjusted for sex in the original dataset, was OR = 8.18 [95% confidence limits (CL): 5.86, 11.43]; after misclassification, it decreased to OR = 3.08 (nominal 95% CL: 2.40, 3.96). The adjusted point estimates from all three approaches were always closer to the 'true' OR than the OR estimated from the unadjusted misclassified smoking data, and the adjusted interval estimates were always wider than the unadjusted interval estimate. When imputed misclassification parameters departed much from the actual misclassification, the 'true' OR was often omitted in the FBA intervals whereas it was always included in the PBA and Bayesian intervals. : These results illustrate how PBA and Bayesian analyses can be used to better account for uncertainty and bias due to measurement error.<br/
Approaches to Daily Monitoring of the SARS-CoV-2 Outbreak in Northern Italy
Italy was the first European country affected by the Sars-Cov-2 pandemic, with the first autochthonous case identified on Feb 21st. Specific control measures restricting social contacts were introduced by the Italian government starting from the beginning of March. In the current study we analyzed public data from the four most affected Italian regions. We (i) estimated the time-varying reproduction number (Rt), the average number of secondary cases that each infected individual would infect at time t, to monitor the positive impact of restriction measures; (ii) applied the generalized logistic and the modified Richards models to describe the epidemic pattern and obtain short-term forecasts. We observed a monotonic decrease of Rt over time in all regions, and the peak of incident cases ~2 weeks after the implementation of the first strict containment measures. Our results show that phenomenological approaches may be useful to monitor the epidemic growth in its initial phases and suggest that costly and disruptive public health controls might have had a positive impact in limiting the Sars-Cov-2 spread in Northern Italy
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