Standing kink waves in sigmoid coronal loops : implications for coronal seismology

Using full three-dimensional magnetohydrodynamic numerical simulations, we study the effects of magnetic field sigmoidity or helicity on the properties of the fundamental kink oscillation of solar coronal loops. Our model consists of a single denser coronal loop, embedded in a plasma with dipolar force-free magnetic field with a constant α-parameter. For the loop with no sigmoidity, we find that the numerically determined oscillation period of the fundamental kink mode matches the theoretical period calculated using WKB theory. In contrast, with increasing sigmoidity of the loop, the actual period is increasingly smaller than the one estimated by WKB theory. Translated through coronal seismology, increasing sigmoidity results in magnetic field estimates that are increasingly shifting toward higher values, and even surpassing the average value for the highest α value considered. Nevertheless, the estimated range of the coronal magnetic field value lies within the minimal/maximal limits, proving the robustness coronal seismology. We propose that the discrepancy in the estimations of the absolute value of the force-free magnetic field could be exploited seismologically to determine the free energy of coronal loops, if averages of the internal magnetic field and density can be reliably estimated by other methods

Point Estimation of States of Finite Quantum Systems

The estimation of the density matrix of a $k$-level quantum system is studied when the parametrization is given by the real and imaginary part of the entries and they are estimated by independent measurements. It is established that the properties of the estimation procedure depend very much on the invertibility of the true state. In particular, in case of a pure state the estimation is less efficient. Moreover, several estimation schemes are compared for the unknown state of a qubit when one copy is measured at a time. It is shown that the average mean quadratic error matrix is the smallest if the applied observables are complementary. The results are illustrated by computer simulations.Comment: 16 pages, 5 figure

Reactivation of the mitosis-promoting factor in postmitotic cardiomyocytes

Cardiomyocytes cease to divide shortly after birth and an irreversible cell cycle arrest is evident accompanied by the downregulation of cyclin-dependent kinase activities. To get a better understanding of the cardiac cell cycle and its regulation, the effect of functional recovery of the mitosis-promoting factor (MPF) consisting of cyclin B1 and the cyclin-dependent kinase Cdc2 was assessed in primary cultures of postmitotic ventricular adult rat cardiomyocytes ( ARC). Gene transfer into ARC was achieved using the adenovirus-enhanced transferrinfection system that was characterized by the absence of cytotoxic events. Simultaneous ectopic expression of wild-type versions of cyclin B1 and Cdc2 was sufficient to induce MPF activity. Reestablished MPF resulted in a mitotic phenotype, marked by an abnormal condensation of the nuclei, histone H3 phosphorylation and variable degree of decay of the contractile apparatus. Although a complete cell division was not observed, the results provided conclusive evidence that cell cycle-related events in postmitotic cardiomyocytes could be triggered by genetic intervention downstream of the G1/S checkpoint. This will be of importance to design novel strategies to overcome the proliferation arrest in adult cardiomyocytes

Measurement of rare isotopologues of nitrous oxide by high-resolution multi-collector mass spectrometry

Rationale: Bulk and position-specific stable isotope characterization of nitrous oxide represents one of the most powerful tools for identifying its environmental sources and sinks. Constraining ^(14)N^(15)N^(18)O and ^(15)N^(14)N^(18)O will add two new dimensions to our ability to uniquely fingerprint N_2O sources. Methods: We describe a technique to measure six singly and doubly substituted isotopic variants of N2O, constraining the values of δ^(15)N, δ^(18)O, ∆^(17)O, ^(15)N site preference, and the clumped isotopomers ^(14)N^(15)N^(18)O and ^(15)N^(14)N^(18)O. The technique uses a Thermo MAT 253 Ultra, a high-resolution multi-collector gas source isotope ratio mass spectrometer. It requires 8–10 hours per sample and ~10 micromoles or more of pure N_2O. Results: We demonstrate the precision and accuracy of these measurements by analyzing N_2O brought to equilibrium in its position-specific and clumped isotopic composition by heating in the presence of a catalyst. Finally, an illustrative analysis of biogenic N_2O from a denitrifying bacterium suggests that its clumped isotopic composition is controlled by kinetic isotope effects in N_2O production. Conclusions: We developed a method for measuring six isotopic variants of N_2O and tested it with analyses of biogenic N_2O. The added isotopic constraints provided by these measurements will enhance our ability to apportion N_2O sources