36 research outputs found

    Radiation and Soret Effects of MHD Nanofluid Flow over a Moving Vertical Moving Plate in Porous Medium

    Get PDF
    We analyzed the magneticfiled, radiation and soret effects of a nanofluid flow over a moving vertical plate in porous medium. We considered two types of nanofluids namely Cu-Ethylene glycol, CuO-Ethylene glycol. The governing partial differential equations of the flow are transformed to ordinary differential equations by using similarity transformation and then solved numerically. The effects of non-dimensional governing parameters namely volume fraction of nano particles,  magneticfiled parameter, radiation parameter, soret number, buoyancy parameter and porosity parameter on the flow, temperature and concentration profiles are discussed and presented graphically. Also, the friction factor and Nusselt and Sherwood numbers are discussed and given in tabular form for two nanofluids separately. Keywords: MHD, Radiation, Soret effect, Porous medium, Nanofluid

    Radiation, inclined magnetic field and cross-diffusion effects on flow over a stretching surface

    Get PDF
    AbstractThe steady two-dimensional flow over a vertical stretching surface in presence of aligned magnetic field, cross-diffusion and radiation effects are considered. The governing partial differential equations are transformed to nonlinear ordinary differential equation by using similarity transformation and then solved numerically by using bvp4c with MATLAB package. The effects of various non-dimensional governing parameters on velocity, temperature, concentration profiles along friction factor, Nusselt and Sherwood numbers are discussed and presented through graphs and tables’.We observed that increase in aligned angle strengthen the magnetic field and decreases the velocity profile of the flow and enhances the heat transfer rate. Comparisons with existed results are presented

    Oral and dermal toxicity of alkenones extracted from Isochrysis species

    Get PDF
    Author Posting. © Bioscience Research Institute, 2020. This article is posted here by permission of Bioscience Research Institute for personal use, not for redistribution. The definitive version was published in McIntosh, K., Sarver, J., Mell, K., Terrero, D. J., Ashby, C. R., Reddy, C., O’Neil, G., Ramapuram, J. B., & Tiwari, A. K. Oral and dermal toxicity of alkenones extracted from Isochrysis species. Frontiers in Bioscience-Landmark, 25(5), (2020): 817–837, https://doi.org/10.2741/4836.Isochrysis is commercially available marine algae used for animal feed, human nutrient supplements, and biodiesel. The Isochrysis species is one of five genera of haptophytes that produces unique, long-chain lipids known as alkenones that are promising new ingredients for green cosmetics, personal care products and pharmaceutical delivery. However, there is a lack of toxicity data for alkenones in animals, thus limiting their use in humans. In this study, we performed acute oral, acute dermal, and repeated 28-day dermal toxicity studies, using female SAS Sprague Dawley Rats. Our behavioral studies indicated that the specific alkenones had no overt behavioural effects at oral doses up to 4000 mg/kg. In the acute and chronic dermal toxicity studies, the alkenones produced less irritation and did not significantly damage the skin based on the Draize skin reaction scale and trans-epidermal water loss readings compared to the positive control, 1% sodium lauryl sulfate. Overall, our results indicated that alkenones are safe in Sprague Dawley rats, suggesting that they could be used for both oral and dermal formulations, although additional studies will be required.This work was supported by the Marine Biological Laboratory Woods Hole Oceanographic Institute (WHOI) under grant (N-126665-01, 2017), Washington Research Foundation, and University of Toledo start-up funding under a grant (F110760) to A.K.T. The authors declare no conflict of interest

    Development of a sustained-release voriconazole-containing thermogel for subconjunctival injection in horses

    Get PDF
    PURPOSE. To determine in vitro release profiles, transcorneal permeation, and ocular injection characteristics of a voriconazole-containing thermogel suitable for injection into the subconjunctival space (SCS). METHODS. In vitro release rate of voriconazole (0.3% and 1.5%) from poly (DL-lactide-coglycolide-b-ethylene glycol-b-DL-lactide-co-glycolide) (PLGA-PEG-PLGA) thermogel was determined for 28 days. A Franz cell diffusion chamber was used to evaluate equine transcorneal and transscleral permeation of voriconazole (1.5% topical solution, 0.3% and 1.5% voriconazole-thermogel) for 24 hours. Antifungal activity of voriconazole released from the 1.5% voriconazole-thermogel was determined via the agar disk diffusion method. Ex vivo equine eyes were injected with liquid voriconazole-thermogel (4°C). Distension of the SCS was assessed ultrasonographically and macroscopically. SCS voriconazole-thermogel injections were performed in a horse 1 week and 2 hours before euthanasia and histopathologic analysis of ocular tissues performed. RESULTS. Voriconazole was released from the PLGA-PEG-PLGA thermogel for more than 21 days in all groups. Release followed first-order kinetics. Voriconazole diffused through the cornea and sclera in all groups. Permeation was greater through the sclerae than corneas. Voriconazole released from the 1.5% voriconazole-thermogel showed antifungal activity in vitro. Voriconazole-thermogel was easily able to be injected into the dorsal SCS where it formed a discrete gel deposit. Voriconazole-thermogel was easily injected in vivo and did not induce any adverse reactions. CONCLUSIONS. Voriconazole-containing thermogels have potential application in treatment of keratomycosis. Further research is required to evaluate their performance in vivo

    Influence of Stefan blowing on nanofluid flow submerged in microorganisms with leading edge accretion or ablation

    Get PDF
    The unsteady forced convective boundary layer flow of viscous incompressible fluid containing both nanoparticles and gyrotactic microorganisms, from a flat surface with leading edge accretion (or ablation), is investigated theoretically. Utilizing appropriate similarity transformations for the velocity, temperature, nanoparticle volume fraction and motile microorganism density, the governing conservation equations are rendered into a system of coupled, nonlinear, similarity ordinary differential equations. These equations, subjected to imposed boundary conditions, are solved numerically using the Runge-Kutta-Fehlberg fourth-fifth order numerical method in the MAPLE symbolic software. Good agreement between our computations and previous solutions is achieved. The effect of selected parameters on flow velocity, temperature, nano-particle volume fraction (concentration) and motile microorganism density function is investigated. Furthermore, tabular solutions are included for skin friction, wall heat transfer rate, nano-particle mass transfer rate and microorganism transfer rate. Applications of the study arise in advanced micro-flow devices to assess nanoparticle toxicity

    Notes for genera: basal clades of Fungi (including Aphelidiomycota, Basidiobolomycota, Blastocladiomycota, Calcarisporiellomycota, Caulochytriomycota, Chytridiomycota, Entomophthoromycota, Glomeromycota, Kickxellomycota, Monoblepharomycota, Mortierellomycota, Mucoromycota, Neocallimastigomycota, Olpidiomycota, Rozellomycota and Zoopagomycota)

    Get PDF
    Compared to the higher fungi (Dikarya), taxonomic and evolutionary studies on the basal clades of fungi are fewer in number. Thus, the generic boundaries and higher ranks in the basal clades of fungi are poorly known. Recent DNA based taxonomic studies have provided reliable and accurate information. It is therefore necessary to compile all available information since basal clades genera lack updated checklists or outlines. Recently, Tedersoo et al. (MycoKeys 13:1--20, 2016) accepted Aphelidiomycota and Rozellomycota in Fungal clade. Thus, we regard both these phyla as members in Kingdom Fungi. We accept 16 phyla in basal clades viz. Aphelidiomycota, Basidiobolomycota, Blastocladiomycota, Calcarisporiellomycota, Caulochytriomycota, Chytridiomycota, Entomophthoromycota, Glomeromycota, Kickxellomycota, Monoblepharomycota, Mortierellomycota, Mucoromycota, Neocallimastigomycota, Olpidiomycota, Rozellomycota and Zoopagomycota. Thus, 611 genera in 153 families, 43 orders and 18 classes are provided with details of classification, synonyms, life modes, distribution, recent literature and genomic data. Moreover, Catenariaceae Couch is proposed to be conserved, Cladochytriales Mozl.-Standr. is emended and the family Nephridiophagaceae is introduced

    MHD non-Newtonian fluid flow over a slendering stretching sheet in the presence of cross-diffusion effects

    No full text
    In this study, we inquired the cross-diffusion effects on the magnetohydrodynamic Williamson fluid flow across a variable thickness stretching sheet by viewing velocity slip. With the aid of Runge-Kutta based shooting process, we resolved the transformed differential equations numerically. The effects of different dimensionless parameters on three usual profiles (velocity, temperature, concentration) along with skin friction coefficient, heat transfer rate and mass transfer rate are examined with the support of plots and tables. Dual solutions are exhibited for two cases i.e., Newtonian fluid and non-Newtonian fluid. Results reveal that the Soret and Dufour numbers have drift to control the thermal and concentration boundary layers. We also found a good agreement of the present results by comparing with the published results

    Effect of nonlinear thermal radiation on non-aligned bio-convective stagnation point flow of a magnetic-nanofluid over a stretching sheet

    No full text
    The current study covers the relative study of non-aligned magnetohydrodynamic stagnation point flow of a nanofluid comprising gyrotactic microorganisms across a stretching sheet in the presence of nonlinear thermal radiation and variable viscosity. The governing equations transitioned as nonlinear ordinary differential equations with suited similarity transformations. With the assistance of Runge-Kutta based shooting method, we derived solutions. Results for oblique and free stream flow cases are exhibited through plots for the parameters of concern. In tabular form, heat and mass transfer rate along with the local density of the motile microorganisms are analyzed for some parameters. It is found that local density of the motile microorganisms is highly influenced by the Biot and Peclet numbers. Rising values of the magnetic field parameter, Biot number, thermal radiation parameter and thermophoresis parameter increase the thermal boundary layer. Bioconvection Peclet number and bioconvection Lewis number have tendency to reduce the density of the motile microorganisms. It is also found that thermal and concentration boundary layers become high in free stream flow when compared with the oblique flow

    Free convective MHD Cattaneo-Christov flow over three different geometries with thermophoresis and Brownian motion

    No full text
    The knowledge of heat and mass transfer of MHD flows over different geometries is very important for heat exchangers design, transpiration, fiber coating, etc. With this initiation, a mathematical model is proposed to investigate the two-dimensional flow, heat and mass transfer of magnetohydrodynamic flow over three different geometries (vertical cone, vertical wedge, and a vertical plate). Cattaneo-Christov heat flux with external magnetic field, thermophoresis and Brownian movement effect are introduced in the model. Runge-Kutta and Newtonâs methods are employed to solve the altered governing nonlinear equations. The influences of the parameters of concern on the common profiles (velocity, temperature, and concentration) are conversed (in three cases). By viewing the same parameters, skin friction coefficient, heat and mass transfer rates are discussed with the assistance of tables. It is discovered that the momentum and thermal boundary layers are non-uniform for the MHD flow over three geometries (vertical cone, wedge, and a plate). Thermal and solutal Grashof numbers regulate the temperature and concentration fields. The heat and mass transfer rates of the flow over a cone are highly influenced by the thermal relaxation parameter. Keywords: MHD, Cattaneo-Christov heat flux, Thermal relaxation, Thermophoresis, Brownian motio

    Dual solutions for three-dimensional

    Get PDF
    In this study we investigated the effect of space and temperature dependent heat generation/absorption on three-dimensional magnetohydrodynamic nanofluid flow over a nonlinearly permeable stretching sheet. After using appropriate self-similarity transformation the governing equations are solved numerically using bvp4c Matlab package. The effects of the non-dimensional governing parameters on velocity, temperature and concentration profiles are discussed with the help of graphs. Also, coefficient of skin friction and Nusselt number is analyzed and presented through tables. It is found that present results have an excellent agreement with the existed studies under some special cases. Results indicate that an increase in space and temperature dependent heat source or sink increases the temperature and concentration profiles of the flow. Dual solutions exist only for certain range of power-law index
    corecore