Internal Kinematics of Distant Field Galaxies: I. Emission Line Widths for a Complete Sample of Faint Blue Galaxies at <z>=0.25

We present measurements of the OII(3727) emission line width for a complete sample of 24 blue field galaxies (21.25=0.25, obtained with the AUTOFIB fibre spectrograph on the Anglo-Australian Telescope. Most emission lines are spectrally resolved, yet all have dispersions sigma<100km/s. Five of the 24 sample members have OII doublet line flux ratios which imply gas densities in excess of 100 cm^-3. The line emission in these galaxies may be dominated by an active nucleus and the galaxies have been eliminated from the subsequent analysis. The remaining 19 linewidths are too large by a factor of two (7sigma significance) to be attributed to turbulent motions within an individual star forming region, and therefore most likely reflect the orbital motion of ionized gas in the galaxy. We use Fabry--Perot observations of nearby galaxies to construct simulated datasets that mimic our observational setup at z=0.25; these allow us to compute the expected distribution of (observable) linewidths sigma_v for a galaxy of a given ``true'' (optical) rotation speed v_c. These simulations include the effects of random viewing angles, clumpy line emission, finite fibre aperture, and internal dust extinction on the emission line profile. We assume a linewidth--luminosity--colour relation: ln[ v_c(M_B,B-R) ] = ln[v_c(-19,1)] - eta*(M_B+10) + zeta*[(B-R)-1] and determine the range of parameters consistent with our data. We find a mean rotation speed of v_c(-19,1)=66+-8km/s (68% confidence limits) for the distant galaxies with M_B=-19 and B-R=1, with a magnitude dependence for v_c of eta=0.07+-0.08, and a colour dependence of zeta =0.28+-0.25. Through comparison with several local samples we show that this value of v_c(-19,1) is significantly lower than the optical rotation speed of present-day galaxies with the same absolute magnitudeComment: TeX Text and Tables, no Figures. Compressed and uuencoded PS file of the complete paper (43 pages including 9 figures) available at http://zwicky.as.arizona.edu/~rix/; submitted to MNRA

KREMLAS: Entwicklung einer kreativen evolutionären Entwurfsmethode für Layoutprobleme in Architektur und Städtebau

Die im vorliegenden Buch dokumentierten Untersuchungen befassen sich mit der Entwicklung von Methoden zur algorithmischen Lösung von Layoutaufgaben im architektonischen Kontext. Layout bezeichnet hier die gestalterisch und funktional sinnvolle Anordnung räumlicher Elemente, z.B. von Parzellen, Gebäuden, Räumen auf bestimmten Maßstabsebenen. Die vorliegenden Untersuchungen sind im Rahmen eines von der Deutschen Forschungsgemeinschaft geförderten Forschungsprojekts entstanden

J Regularization Improves Imbalanced Multiclass Segmentation

We propose a new loss formulation to further advance the multiclass segmentation of cluttered cells under weakly supervised conditions. When adding a Youden's J statistic regularization term to the cross entropy loss we improve the separation of touching and immediate cells, obtaining sharp segmentation boundaries with high adequacy. This regularization intrinsically supports class imbalance thus eliminating the necessity of explicitly using weights to balance training. Simulations demonstrate this capability and show how the regularization leads to correct results by helping advancing the optimization when cross entropy stagnates. We build upon our previous work on multiclass segmentation by adding yet another training class representing gaps between adjacent cells. This addition helps the classifier identify narrow gaps as background and no longer as touching regions. We present results of our methods for 2D and 3D images, from bright field images to confocal stacks containing different types of cells, and we show that they accurately segment individual cells after training with a limited number of images, some of which are poorly annotated

Infrastructure for genomic interactions: Bioconductor classes for Hi-C, ChIA-PET and related experiments [version 1; referees: 2 approved]

The study of genomic interactions has been greatly facilitated by techniques such as chromatin conformation capture with high-throughput sequencing (Hi-C). These genome-wide experiments generate large amounts of data that require careful analysis to obtain useful biological conclusions. However, development of the appropriate software tools is hindered by the lack of basic infrastructure to represent and manipulate genomic interaction data. Here, we present the InteractionSet package that provides classes to represent genomic interactions and store their associated experimental data, along with the methods required for low-level manipulation and processing of those classes. The InteractionSet package exploits existing infrastructure in the open-source Bioconductor project, while in turn being used by Bioconductor packages designed for higher-level analyses. For new packages, use of the functionality in InteractionSet will simplify development, allow access to more features and improve interoperability between packages.Cancer Research UK (Grant ID: A17197)This is the final version of the article. It first appeared from F1000 Research via http://dx.doi.org/10.12688/f1000research.8759.

Cultivation and analysis of anthocyanins containing-, blue potatoes

Anthocyanins, as secondary plant substance in different agricultural crops such as potatoes and cereals have positive effects on health due to their antioxidant capacity. Therefore food industry, nutritional medicine and consumers have an increasing interest in these crops. The objectives of the interdisciplinary research project (AGIP) starting in march 2006 are ascertainment and assessment of the impact of different agricultural production processes and production intensities. Furthermore, the impact of different ways of food preparation concerning anthocyanin content and antioxidative capacity in selected cultivated plants will be tested. Main focus will be on potatoes due to the fact that potatoes as a staple food are consumed in large quantities. Therefore potatoes can be an important quantitative source for anthocyanins

Consolidation of complex events via reinstatement in posterior cingulate cortex

It is well-established that active rehearsal increases the efficacy of memory consolidation. It is also known that complex events are interpreted with reference to prior knowledge. However, comparatively little attention has been given to the neural underpinnings of these effects. In healthy adult humans, we investigated the impact of effortful, active rehearsal on memory for events by showing people several short video clips and then asking them to recall these clips, either aloud (Experiment 1) or silently while in an MRI scanner (Experiment 2). In both experiments, actively rehearsed clips were remembered in far greater detail than unrehearsed clips when tested a week later. In Experiment 1, highly similar descriptions of events were produced across retrieval trials, suggesting a degree of semanticization of the memories had taken place. In Experiment 2, spatial patterns of BOLD signal in medial temporal and posterior midline regions were correlated when encoding and rehearsing the same video. Moreover, the strength of this correlation in the posterior cingulate predicted the amount of information subsequently recalled. This is likely to reflect a strengthening of the representation of the video's content. We argue that these representations combine both new episodic information and stored semantic knowledge (or "schemas"). We therefore suggest that posterior midline structures aid consolidation by reinstating and strengthening the associations between episodic details and more generic schematic information. This leads to the creation of coherent memory representations of lifelike, complex events that are resistant to forgetting, but somewhat inflexible and semantic-like in nature