Results and prospects on registration of reflected Cherenkov light of EAS from cosmic particles above 10^{15} eV

We give an overview of the SPHERE experiment based on detection of reflected Vavilov-Cherenkov radiation (Cherenkov light) from extensive air showers in the energy region E>10^{15} eV. A brief history of the reflected Cherenkov light technique is given; the observations carried out with the SPHERE-2 detector are summarized; the methods of the experimental datasample analysis are described. The first results on the primary cosmic ray all-nuclei energy spectrum and mass composition are presented. Finally, the prospects of the SPHERE experiment and the reflected Cherenkov light technique are given.Comment: 4 pages, 3 figures, Proc. PANIC-201

Characterization of SU(1,1) coherent states in terms of affine group wavelets

The Perelomov coherent states of SU(1,1) are labeled by elements of the quotient of SU(1,1) by the compact subgroup. Taking advantage of the fact that this quotient is isomorphic to the affine group of the real line, we are able to parameterize the coherent states by elements of that group or equivalently by points in the half-plane. Such a formulation permits to find new properties of the SU(1,1) coherent states and to relate them to affine wavelets.Comment: 11 pages, latex, to be published in J. Phys. A : Math. Ge

Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration.

Gas1 and Boc/Cdon act as co-receptors in the vertebrate Hedgehog signalling pathway, but the nature of their interaction with the primary Ptch1/2 receptors remains unclear. Here we demonstrate, using primordial germ cell migration in mouse as a developmental model, that specific hetero-complexes of Ptch2/Gas1 and Ptch1/Boc mediate the process of Smo de-repression with different kinetics, through distinct modes of Hedgehog ligand reception. Moreover, Ptch2-mediated Hedgehog signalling induces the phosphorylation of Creb and Src proteins in parallel to Gli induction, identifying a previously unknown Ptch2-specific signal pathway. We propose that although Ptch1 and Ptch2 functionally overlap in the sequestration of Smo, the spatiotemporal expression of Boc and Gas1 may determine the outcome of Hedgehog signalling through compartmentalisation and modulation of Smo-downstream signalling. Our study identifies the existence of a divergent Hedgehog signal pathway mediated by Ptch2 and provides a mechanism for differential interpretation of Hedgehog signalling in the germ cell niche

Lawson criterion for ignition exceeded in an inertial fusion experiment

For more than half a century, researchers around the world have been engaged in attempts to achieve fusion ignition as a proof of principle of various fusion concepts. Following the Lawson criterion, an ignited plasma is one where the fusion heating power is high enough to overcome all the physical processes that cool the fusion plasma, creating a positive thermodynamic feedback loop with rapidly increasing temperature. In inertially confined fusion, ignition is a state where the fusion plasma can begin "burn propagation" into surrounding cold fuel, enabling the possibility of high energy gain. While "scientific breakeven" (i.e., unity target gain) has not yet been achieved (here target gain is 0.72, 1.37 MJ of fusion for 1.92 MJ of laser energy), this Letter reports the first controlled fusion experiment, using laser indirect drive, on the National Ignition Facility to produce capsule gain (here 5.8) and reach ignition by nine different formulations of the Lawson criterion