10,433 research outputs found

    Law and the Poor in Rural India: The Prospects for Legal Aid

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    Movements come and go, in society at large no less than in the academy. Theories are refined; they inspire action, engender criticism, and secure successes and failures. Modern programs for social intervention in the contemporary United States, particularly those designed to alleviate poverty or to secure equal treatment for unpopular minorities (the have-nots ), have lately fallen on harder times. An obvious sign of this trend is the federal government\u27s curtailment of financial support. Recent signs from the Supreme Court also indicate a major withdrawal from past judicial activism in favor of the have-nots.\u27 Criticism of pro- grams of social intervention, however, has come not only from conservative politicians, but also from both the left and right of the scholarly community. A crisis of confidence has evolved in the government\u27s ability to help engineer a better society. The subject of this article involves two such movements: free legal aid (and related public interest litigation) and law and development (particularly the application of Western legal experience to the study of developing countries). Both movements have suffered intense criticism. Nevertheless, a new field has emerged-free legal aid in developing countries-which somewhat surprisingly has attracted support from scholars, governments, lawyers, and international institutions. As with other movements, legal aid in developing countries has undergone theoretical refinement. It has engendered action, criticism, some successes, and many failures. This is not to say that criticisms of both left and right have been so devastating as to invalidate these pro- grams for social intervention. Instead, many argue for program improvement and not for elimination. There exists, however, some profound criticisms of public interest litigation, legal aid, and law and development

    Law and the Poor in Rural India: The Prospects for Legal Aid

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    The Angular Momentum Operator in the Dirac Equation

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    The Dirac equation in spherically symmetric fields is separated in two different tetrad frames. One is the standard cartesian (fixed) frame and the second one is the diagonal (rotating) frame. After separating variables in the Dirac equation in spherical coordinates, and solving the corresponding eingenvalues equations associated with the angular operators, we obtain that the spinor solution in the rotating frame can be expressed in terms of Jacobi polynomials, and it is related to the standard spherical harmonics, which are the basis solution of the angular momentum in the Cartesian tetrad, by a similarity transformation.Comment: 13 pages,CPT-94/P.3027,late

    The Use of the Decomposition Principle in Making Judgments

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    One hundred and fifty-one subjects were randomly divided into two groups of roughly equal size. One group was asked to respond to a decomposed version of a problem and the other group was presented with the direct form of the problem. The results provided support for the hypotheses that people can make better judgments when they use the principle of decomposition; and that decomposition is especially valuable for those problems where the subject knows little. The results suggest that accuracy may be improved if the subject provides the data and the computer analyzes it, than if both steps were done implicitly by the subjects

    Identification of Binding Regions of Bilirubin in the Ligand-Binding Pocket of the Peroxisome Proliferator-Activated Receptor-A (PPARalpha)

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    Recent work has shown that bilirubin has a hormonal function by binding to the peroxisome proliferator-activated receptor-Ī± (PPARĪ±), a nuclear receptor that drives the transcription of genes to control adiposity. Our previous in silico work predicted three potential amino acids that bilirubin may interact with by hydrogen bonding in the PPARĪ± ligand-binding domain (LBD), which could be responsible for the ligand-induced function. To further reveal the amino acids that bilirubin interacts with in the PPARĪ± LBD, we harnessed bilirubinā€™s known fluorescent properties when bound to proteins such as albumin. Our work here revealed that bilirubin interacts with threonine 283 (T283) and alanine 333 (A333) for ligand binding. Mutational analysis of T283 and A333 showed significantly reduced bilirubin binding, reductions of 11.4% and 17.0%, respectively. Fenofibrate competitive binding studies for the PPARĪ± LBD showed that bilirubin and fenofibrate possibly interact with different amino acid residues. Furthermore, bilirubin showed no interaction with PPARĪ³. This is the first study to reveal the amino acids responsible for bilirubin binding in the ligand-binding pocket of PPARĪ±. Our work offers new insight into the mechanistic actions of a well-known molecule, bilirubin, and new fronts into its mechanisms

    GridCertLib: a Single Sign-on Solution for Grid Web Applications and Portals

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    This paper describes the design and implementation of GridCertLib, a Java library leveraging a Shibboleth-based authentication infrastructure and the SLCS online certificate signing service, to provide short-lived X.509 certificates and Grid proxies. The main use case envisioned for GridCertLib, is to provide seamless and secure access to Grid/X.509 certificates and proxies in web applications and portals: when a user logs in to the portal using Shibboleth authentication, GridCertLib can automatically obtain a Grid/X.509 certificate from the SLCS service and generate a VOMS proxy from it. We give an overview of the architecture of GridCertLib and briefly describe its programming model. Its application to some deployment scenarios is outlined, as well as a report on practical experience integrating GridCertLib into portals for Bioinformatics and Computational Chemistry applications, based on the popular P-GRADE and Django softwares.Comment: 18 pages, 1 figure; final manuscript accepted for publication by the "Journal of Grid Computing
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