The effect of social networks on the development of gastronomy – the way forward to the development of gastronomy tourism in Serbia

Purpose: To evaluate some of the current discussions about the possible impacts of social networks on the development of gastronomy in the Republic of Serbia. There could be either positive and/or negative impacts and this viewpoint provides some reflection on what the future might hold for some if not many tourism destinations in Serbia and the region when the tourism industry restarts after the pandemic of Covid-19 virus. Design/methodology/approach: The research was conducted in December 2021, on a total of 244 respondents in three cities in Serbia. SPSS software was used, version 26.00, and the obtained data were analyzed by descriptive statistics. Then, to determine the structure of the questionnaire and the percentage of variance, an exploratory factor analysis was performed together with a higher order factor analysis, in order to obtain the desired number of factors. Subsequently, the authors used multiple regression analysis to confirm the significance of the predictors. The goal of the research was to determine whether, and to what extent, social networks can predict the choice of restaurants and gastronomic offers in Serbia. Serbian gastronomy has a great influence on the development of tourism, so this research has a wide scientific and practical contribution. Findings: This paper provides a context and viewpoint on the possible implications of impacts of social networks on the development of gastronomy in the Republic of Serbia in the future. It has been proven that social networks can have an impact on the development of gastronomy and tourism itself. Research limitations/implications: To examine the impact of social networks on the development of gastronomy, the authors conducted a survey online due to the current Covid-19 pandemic. The limitation of this research was precisely that the authors did not have the opportunity to conduct the research live due to the Covid-19 pandemic. It is recommended that such surveys be conducted live in direct contact with respondents in the future in order to obtain a larger sample with fully completed questionnaires. Practical implications: The importance of social networks is increasingly a topic of study of world research, especially when it comes to gastronomy, which is becoming increasingly important as an activity in the tourism industry. The results indicate that the greatest importance in predicting the choice of restaurants and gastronomic offers has social networks and marketing. The importance of the work is reflected in the recognition of the importance of social networks, in order to better place Serbian gastronomy. Social implications: This paper offers a synthesis of views that fosters an understanding of the possibility of impacts of social networks on the development of gastronomy in the Republic of Serbia before and after the Covid-19 pandemic. Originality/value: The viewpoint proffered in this paper provides scope for a rapid evaluation of the current status of gastronomy tourism in Serbia which can help practitioners and researchers in the faster and better development of gastronomy and tourism

Optical properties of NaxV2O5

The optical properties of sodium-deficient NaxV2O5 (0.85 < x <1) single crystals are analyzed in the wide energy range, from 0.012 to 4.5 eV, using ellipsometry, infrared reflectivity, and Raman scattering techniques. The material remains insulating up to the maximal achieved hole concentration of about 15%. In sodium deficient samples the optical absorption peak associated to the fundamental electronic gap develops at about 0.44 eV. It corresponds to the transition between vanadium dxy and the impurity band, which forms in the middle of the pure NaV2O5 gap. Raman spectra measured with incident photon energy larger then 2 eV show strong resonant behavior, due to the presence of the hole-doping activated optical transitions, peaked at 2.8 eV.Comment: 7 pages, 4 fugures, to be published in PR

Non-imaging technologies for designing a hybrid photovoltaic and solar thermal collector.

The sun is the world&#039;s most abundant energy source and means of harvesting it include photovoltaic cells to create electricity and solar thermal collectors to generate heat. Low temperature heat can be used for domestic applications where in urban environments available space is often limited. By combining solar thermal and photovoltaics in one system, roof space can be saved and potentially eciency can be increased. Photovoltaic technologies can only convert photons with energies above their bandgap to electricity, with the remainder of the solar spectrum wastefully generating heat. In a hybrid conguration that heat is not wasted but collected instead. The work done in this thesis investigates and then combines two nonimaging types of concentrating solar technologies: the luminescent solar concentrator that generates electricity via photovoltaic cells, conventionally used in the built environment and the compound parabolic concentrator, used for capturing solar thermal energy. LSCs combined with exible SLIVER solar cells were investigated in a new circular conguration and were found to work well although the manual fabrication nature of these devices limited their eciency. Various high quantum yield uorophores were also investigated and it was found that performance of the LSCs was highly dependent on maximising the Stokes-shift of the uorophore to minimise losses. Following on from this work, the luminescent solar concentrator in a new application of the technology, was used as a cover for the solar thermal collector (the CPC) whilst at the same time concentrating a band of light to its edges where solar cells convert photons to electricity. The capture of a part of the solar spectrum in the LSC is done with uorescent particles whilst the rest of the solar spectrum can be captured as thermal energy in the CPC, essentially coming up with a new spectral splitting hybrid solar collector. A small prototype hybrid CPC and LSC collector was tested in the lab under a solar simulator. This proof of concept device compared a high transmission and low transmission LSC and demonstrated the experimental basis of the new type of PV-T collector. An outdoors ow experiment was undertaken, measuring instantaneous thermal eciency and electrical output

Insight into phylogenomic bias of blaVIM-2 or blaNDM-1 dissemination amongst carbapenem resistant Pseudomonas aeruginosa

Objectives: Pseudomonas aeruginosa (P. aeruginosa) are ubiquitous opportunistic pathogens that combine intrinsic and acquired multidrug resistance phenotypes. Due to different types of acquired genes, carbapenem resistance has been expanding in this species. This study hypothesised that the spread of carbapenem resistance among P. aeruginosa is influenced by phylogenomic features, being distinct for different genes. Methods: To test this hypothesis, the genomes of P. aeruginosa harbouring bla VIM-2 or bla NDM-1 genes were compared. The bla VIM-2 gene was selected because, although frequent, it is almost restricted to this species and bla NDM-1 gene due to its wide interspecies distribution. A group of genomes harbouring the genes bla VIM-2 (n = 116) or bla NDM-1 (n = 27), available in GenBank, was characterised based on core phylogenomic analysis, functional categories in the accessory genome and mobile genetic elements flanking the selected genes. Results: Most bla VIM-2 gene hosts belonged to multilocus sequence types (ST) ST111 (n = 32 of 116) and ST233 (n = 27 of 116) and were reported in Europe (n = 75 of 116). The bla NDM-1 gene hosts were distributed by different STs (ST38, ST773, ST235, ST357 and ST654), frequently from Asia (n = 11 of 27). Significant differences in the prevalence of functional protein/enzyme annotations per number of accessory genomes were observed between bla VIM-2+ and bla NDM-1+. The bla VIM-2 gene was frequently inserted in the Tn402-like and Tn21 transposons family and rarely in IS6100, while bla NDM-1 gene was preferentially flanked by ISAba125 and ble MBL genes or associated with IS91 insertion sequence. Conclusion: The hypothesis that carbapenem resistance gene acquisition is not random among phylogenomic lineages was confirmed, suggesting the importance of phylogeny in the dissemination of antibiotic resistance genes.info:eu-repo/semantics/publishedVersio

Novel mechanism of bacteriocin secretion and immunity carried out by lactococcal multidrug resistance proteins

A natural isolate of Lactococcus lactis was shown to produce two narrow spectrum class II bacteriocins, designated LsbA and LsbB. The cognate genes are located on a 5.6-kb plasmid within a gene cluster specifying LmrB, an ATP-binding cassette-type multidrug resistance transporter protein. LsbA is a hydrophobic peptide that is initially synthesized with an N-terminal extension. The housekeeping surface proteinase HtrA was shown to be responsible for the cleavage of precursor peptide to yield the active bacteriocin. LsbB is a relatively hydrophilic protein synthesized without an N-terminal leader sequence or signal peptide. The secretion of both polypeptides was shown to be mediated by LmrB. An L. lactis strain lacking plasmid-encoded LmrB and the chromosomally encoded LmrA is unable to secrete either of the two bacteriocins. Complementation of the strain with an active LmrB protein resulted in restored export of the two polypeptides across the cytoplasmic membrane. When expressed in an L. lactis strain that is sensitive to LsbA and LsbB, LmrB was shown to confer resistance toward both bacteriocins. It does so, most likely, by removing the two polypeptides from the cytoplasmic membrane. This is the first report in which a multidrug transporter protein is shown to be involved in both secretion and immunity of antimicrobial peptides.

Optimization of Quercetin Extraction from Green Tea (Camellia sinensis) Using Central Composite Design, and the Pharmacological Activity of the Extract

The aim of this paper was to optimize an extraction procedure of quercetin from green tea using central composite design. Extraction time, ethanol concentration, and solid to liquid ratio were selected as the independent variables, while quercetin yield was defined as a response. The impact of factors and their interactions on the quercetin yield was studied based on the results of ANOVA test. The extraction time of 58.5 min, ethanol concentration of 94.7 % (v/v), and solid to liquid ratio of 1:19.4 (m/v) were found as the optimal conditions. The experimental confirmation of the proposed optimal conditions indicated that there was a good agreement between the experimental and predicted values. In addition to quercetin, the presence of 17 bioactive compounds was confirmed in the green tea extract using mass spectrometry method. Antioxidant, antimicrobial and antitumor activity of the optimal extract was determined using DPPH assay, disk diffusion method, and MTT assay, respectively

Optimization of technological procedure for amygdalin isolation from plum seeds (Pruni domesticae semen)

The process of amygdalin extraction from plum seeds was optimized using central composite design (CCD) and multilayer perceptron (MLP). The effect of time, ethanol concentration, solid-to-liquid ratio, and temperature on the amygdalin content in the extracts was estimated using both mathematical models. The MLP 4-3-1 with exponential function in hidden layer and linear function in output layer was used for describing the extraction process. MLP model was more superior compared with CCD model due to better prediction ability. According to MLP model, the suggested optimal conditions are: time of 120 min, 100% (v/v) ethanol, solid-to liquid ratio of 1:25 (m/v) and temperature of 34.4 degrees C. The predicted value of amygdalin content in the dried extract (25.42 g per 100 g) at these conditions was experimentally confirmed (25.30 g per 100 g of dried extract). Amygdalin (>90%) was isolated from the complex extraction mixture and structurally characterized by FT-IR, UV, and MS methods

Lung Injury Prevention with Aspirin (LIPS-A): a Protocol for a Multicentre Randomised Clinical Trial in Medical Patients at High Risk of Acute Lung Injury

Introduction: Acute lung injury (ALI) is a devastating condition that places a heavy burden on public health resources. Although the need for effective ALI prevention strategies is increasingly recognised, no effective preventative strategies exist. The Lung Injury Prevention Study with Aspirin (LIPS-A) aims to test whether aspirin (ASA) could prevent and/or mitigate the development of ALI. Methods and analysis LIPS-A is a multicentre, double-blind, randomised clinical trial testing the hypothesis that the early administration of ASA will result in a reduced incidence of ALI in adult patients at high risk. This investigation will enrol 400 study participants from 14 hospitals across the USA. Conditional logistic regression will be used to test the primary hypothesis that early ASA administration will decrease the incidence of ALI. Ethics and dissemination Safety oversight will be under the direction of an independent Data and Safety Monitoring Board (DSMB). Approval of the protocol was obtained from the DSMB prior to enrolling the first study participant. Approval of both the protocol and informed consent documents were also obtained from the institutional review board of each participating institution prior to enrolling study participants at the respective site. In addition to providing important clinical and mechanistic information, this investigation will inform the scientific merit and feasibility of a phase III trial on ASA as an ALI prevention agent. The findings of this investigation, as well as associated ancillary studies, will be disseminated in the form of oral and abstract presentations at major national and international medical specialty meetings. The primary objective and other significant findings will also be presented in manuscript form. All final, published manuscripts resulting from this protocol will be submitted to Pub Med Central in accordance with the National Institute of Health Public Access Policy